Constantinos Chronis

2.9k total citations · 2 hit papers
27 papers, 1.9k citations indexed

About

Constantinos Chronis is a scholar working on Molecular Biology, Genetics and Epidemiology. According to data from OpenAlex, Constantinos Chronis has authored 27 papers receiving a total of 1.9k indexed citations (citations by other indexed papers that have themselves been cited), including 24 papers in Molecular Biology, 4 papers in Genetics and 3 papers in Epidemiology. Recurrent topics in Constantinos Chronis's work include CRISPR and Genetic Engineering (11 papers), Pluripotent Stem Cells Research (9 papers) and Epigenetics and DNA Methylation (8 papers). Constantinos Chronis is often cited by papers focused on CRISPR and Genetic Engineering (11 papers), Pluripotent Stem Cells Research (9 papers) and Epigenetics and DNA Methylation (8 papers). Constantinos Chronis collaborates with scholars based in United States, United Kingdom and Germany. Constantinos Chronis's co-authors include Kathrin Plath, Giancarlo Bonora, Jason Ernst, Shan Sabri, Bernadett Papp, Matteo Pellegrini, Hyunsoo Rho, Alexander R. Terry, Nissim Hay and Stefan Butz and has published in prestigious journals such as Nature, Cell and Nucleic Acids Research.

In The Last Decade

Constantinos Chronis

25 papers receiving 1.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Cooperative Binding of Transcription Factors Orchestrates Reprogramming

2017 375 citations Constantinos Chronis, Petko Fiziev et al. Cell profile →
Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosis

2023 194 citations Hyunsoo Rho, Alexander R. Terry et al. Cell Metabolism profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Constantinos Chronis United States	18	1.6k	280	243	148	106	27	1.9k
Jörg Bungert United States	29	2.0k 1.2×	347 1.2×	244 1.0×	97 0.7×	176 1.7×	66	2.3k
Eric M. Mendenhall United States	13	1.9k 1.2×	368 1.3×	177 0.7×	140 0.9×	47 0.4×	27	2.1k
Stacy A. Marshall United States	23	1.8k 1.1×	150 0.5×	189 0.8×	85 0.6×	142 1.3×	26	2.0k
Daniel S. Day United States	12	2.1k 1.3×	255 0.9×	297 1.2×	351 2.4×	59 0.6×	13	2.4k
Douglas Vernimmen United Kingdom	21	1.4k 0.9×	361 1.3×	197 0.8×	158 1.1×	104 1.0×	31	1.8k
Sundeep Kalantry United States	25	1.7k 1.1×	668 2.4×	263 1.1×	86 0.6×	77 0.7×	42	2.0k
Ramya Raviram United States	18	1.5k 0.9×	194 0.7×	175 0.7×	282 1.9×	63 0.6×	22	1.7k
Bernhard Lehnertz Canada	16	1.6k 1.0×	299 1.1×	93 0.4×	178 1.2×	322 3.0×	24	2.0k
Nicholas Shukeir Germany	14	1.2k 0.7×	142 0.5×	185 0.8×	167 1.1×	39 0.4×	17	1.4k
Jennifer N. Cech United States	10	892 0.5×	201 0.7×	115 0.5×	93 0.6×	42 0.4×	13	1.2k

Countries citing papers authored by Constantinos Chronis

Since Specialization

Citations

This map shows the geographic impact of Constantinos Chronis's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Constantinos Chronis with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Constantinos Chronis more than expected).

Fields of papers citing papers by Constantinos Chronis

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Constantinos Chronis. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Constantinos Chronis. The network helps show where Constantinos Chronis may publish in the future.

Co-authorship network of co-authors of Constantinos Chronis

This figure shows the co-authorship network connecting the top 25 collaborators of Constantinos Chronis. A scholar is included among the top collaborators of Constantinos Chronis based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Constantinos Chronis. Constantinos Chronis is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Zhao, Siyuan, Debasish Chattopadhyay, G. Elisabeta Marai, et al.. (2025). ChromPolymerDB: a high-resolution database of single-cell 3D chromatin structures for functional genomics. Nucleic Acids Research. 54(D1). D994–D1004. 1 indexed citations

Zhang, Sen, Xiaoping Du, Mortimer Poncz, et al.. (2025). Platelet factor 4 regulates hematopoietic stem cell aging. Blood. 146(23). 2765–2778. 1 indexed citations

Rho, Hyunsoo, Alexander R. Terry, Constantinos Chronis, & Nissim Hay. (2023). Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosis. Cell Metabolism. 35(8). 1406–1423.e8. 194 indexed citations breakdown →

Li, Jingsheng, et al.. (2022). A One-step strategy to target essential factors with auxin-inducible degron system in mouse embryonic stem cells. Frontiers in Cell and Developmental Biology. 10. 964119–964119. 5 indexed citations

Liang, Jie, et al.. (2022). Reprogramming cell fates towards novel cancer immunotherapies. Current Opinion in Pharmacology. 67. 102312–102312.

Pandya‐Jones, Amy, Yolanda Markaki, Jacques Serizay, et al.. (2020). A protein assembly mediates Xist localization and gene silencing. Nature. 587(7832). 145–151. 137 indexed citations

Zhang, Wensheng, Constantinos Chronis, Xi Chen, et al.. (2019). The BAF and PRC2 Complex Subunits Dpf2 and Eed Antagonistically Converge on Tbx3 to Control ESC Differentiation. Cell stem cell. 24(1). 138–152.e8. 32 indexed citations

Bonora, Giancarlo, Liudmilla Rubbi, Marco Morselli, et al.. (2019). DNA methylation estimation using methylation-sensitive restriction enzyme bisulfite sequencing (MREBS). PLoS ONE. 14(4). e0214368–e0214368. 16 indexed citations

Sun, Fei, Constantinos Chronis, Xiao‐Fen Chen, et al.. (2018). Promoter-Enhancer Communication Occurs Primarily within Insulated Neighborhoods. Molecular Cell. 73(2). 250–263.e5. 59 indexed citations

10.

Pasque, Vincent, Rahul Karnik, Constantinos Chronis, et al.. (2018). X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs. Stem Cell Reports. 10(5). 1537–1550. 32 indexed citations

11.

Ohashi, Minori, Denise E. Allen, Peiyee Lee, et al.. (2018). Loss of MECP2 Leads to Activation of P53 and Neuronal Senescence. Stem Cell Reports. 10(5). 1453–1463. 56 indexed citations

12.

Xue, Yong, Suman Pradhan, Fei Sun, et al.. (2017). Mot1, Ino80C, and NC2 Function Coordinately to Regulate Pervasive Transcription in Yeast and Mammals. Molecular Cell. 67(4). 594–607.e4. 33 indexed citations

13.

Chronis, Constantinos, Petko Fiziev, Bernadett Papp, et al.. (2017). Cooperative Binding of Transcription Factors Orchestrates Reprogramming. Cell. 168(3). 442–459.e20. 375 indexed citations breakdown →

14.

Sahakyan, Anna, Rachel Kim, Constantinos Chronis, et al.. (2016). Human Naive Pluripotent Stem Cells Model X Chromosome Dampening and X Inactivation. Cell stem cell. 20(1). 87–101. 163 indexed citations

15.

Sridharan, Rupa, Michelle Gonzales-Cope, Constantinos Chronis, et al.. (2013). Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency. Nature Cell Biology. 15(7). 872–882. 172 indexed citations

16.

Denholtz, Matthew, Giancarlo Bonora, Constantinos Chronis, et al.. (2013). Long-Range Chromatin Contacts in Embryonic Stem Cells Reveal a Role for Pluripotency Factors and Polycomb Proteins in Genome Organization. Cell stem cell. 13(5). 602–616. 204 indexed citations

17.

Gaymes, Terry J., Constantinos Chronis, Barbara Czepulkowski, et al.. (2010). Reducing MCM levels in human primary T cells during the G0→G1 transition causes genomic instability during the first cell cycle. Oncogene. 29(26). 3803–3814. 36 indexed citations

18.

Ho, Ritchie, Constantinos Chronis, & Kathrin Plath. (2010). Mechanistic insights into reprogramming to induced pluripotency. Journal of Cellular Physiology. 226(4). 868–878. 37 indexed citations

19.

Smith, Alexander, Constantinos Chronis, Manolis Christodoulakis, et al.. (2009). Epigenetics of human T cells during the G₀→G₁ transition. Genome Research. 19(8). 1325–1337. 17 indexed citations

20.

Raj, Kavita, Aloysius Ho, Constantinos Chronis, et al.. (2007). CDKN2B methylation status and isolated chromosome 7 abnormalities predict responses to treatment with 5-azacytidine. Leukemia. 21(9). 1937–1944. 114 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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