Constantinos Chronis

2.9k citations

27 papers · 1.9k indexed · 2 hit papers · h-index 18

Co-authors: Kathrin Plath Giancarlo Bonora Jason Ernst Shan Sabri Bernadett Papp Matteo Pellegrini Hyunsoo Rho Alexander R. Terry
Topics: CRISPR and Genetic Engineering (11 papers)Pluripotent Stem Cells Research (9 papers)Epigenetics and DNA Methylation (8 papers)
Cited by: Molecular Biology Aging Cancer Research
Journals: Nature Cell Nucleic Acids Research
Partner nations: United States United Kingdom Germany

In The Last Decade

Constantinos Chronis

25 papers receiving 1.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Cooperative Binding of Transcription Factors Orchestrates Reprogramming

2017 375 citations Constantinos Chronis, Petko Fiziev et al. Cell profile →
Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosis

2023 194 citations Hyunsoo Rho, Alexander R. Terry et al. Cell Metabolism profile →

Peers

Countries citing papers authored by Constantinos Chronis

Since Specialization

Citations

This map shows the geographic impact of Constantinos Chronis's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Constantinos Chronis with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Constantinos Chronis more than expected).

Fields of papers citing papers by Constantinos Chronis

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Constantinos Chronis. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Constantinos Chronis. The network helps show where Constantinos Chronis may publish in the future.

Co-authorship network of co-authors of Constantinos Chronis

This figure shows the co-authorship network connecting the top 25 collaborators of Constantinos Chronis. A scholar is included among the top collaborators of Constantinos Chronis based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Constantinos Chronis. Constantinos Chronis is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	ChromPolymerDB: a high-resolution database of single-cell 3D chromatin structures for functional genomics 2025 ·Nucleic Acids Research ·(unknown),(unknown),Siyuan Zhao,(unknown),(unknown),(unknown),Debasish Chattopadhyay,G. Elisabeta Marai,Zhifeng Shao,Jie Liang,Daniel M. Czajkowsky,Constantinos Chronis	1
2	Platelet factor 4 regulates hematopoietic stem cell aging 2025 ·Blood ·Sen Zhang,(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),Xiaoping Du,Mortimer Poncz,Sang‐Ging Ong,Claus Nerlov,Maria Maryanovich,Constantinos Chronis,Sandra Pinho	1
3	Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosisbreakdown → 2023 ·Cell Metabolism ·Hyunsoo Rho,Alexander R. Terry,Constantinos Chronis,Nissim Hay	194
4	A One-step strategy to target essential factors with auxin-inducible degron system in mouse embryonic stem cells 2022 ·Frontiers in Cell and Developmental Biology ·Jingsheng Li,(unknown),(unknown),(unknown),Xin Huang,Constantinos Chronis,Ying Ye,Wensheng Zhang	5
5	Reprogramming cell fates towards novel cancer immunotherapies 2022 ·Current Opinion in Pharmacology ·(unknown),(unknown),(unknown),(unknown),(unknown),Jie Liang,Constantinos Chronis	0
6	A protein assembly mediates Xist localization and gene silencing 2020 ·Nature ·Amy Pandya‐Jones,Yolanda Markaki,Jacques Serizay,Tsotne Chitiashvili,Walter Mancia,Andrey Damianov,Constantinos Chronis,Bernadett Papp,Chun‐Kan Chen,(unknown),Xiaojun Wang,Anthony Chau,Shan Sabri,Heinrich Leonhardt,Sika Zheng,Mitchell Guttman,Douglas L. Black,Kathrin Plath	137
7	The BAF and PRC2 Complex Subunits Dpf2 and Eed Antagonistically Converge on Tbx3 to Control ESC Differentiation 2019 ·Cell stem cell ·Wensheng Zhang,Constantinos Chronis,Xi Chen,(unknown),(unknown),Mercedes Pardo,Liangliang Chen,Guangming Wu,Zhexin Zhu,Yong Yu,Lu Yu,Jyoti S. Choudhary,Jennifer Nichols,Mana M. Parast,Boris Greber,Pelin Sahlén,Kathrin Plath	32
8	DNA methylation estimation using methylation-sensitive restriction enzyme bisulfite sequencing (MREBS) 2019 ·PLoS ONE ·Giancarlo Bonora,Liudmilla Rubbi,Marco Morselli,Feiyang Ma,Constantinos Chronis,Kathrin Plath,Matteo Pellegrini	16
9	Promoter-Enhancer Communication Occurs Primarily within Insulated Neighborhoods 2018 ·Molecular Cell ·Fei Sun,Constantinos Chronis,(unknown),Xiao‐Fen Chen,Trent Su,Fides D. Lay,Kathrin Plath,Siavash K. Kurdistani,Michael Carey	59
10	X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs 2018 ·Stem Cell Reports ·Vincent Pasque,Rahul Karnik,Constantinos Chronis,(unknown),Justin Langerman,Giancarlo Bonora,Juan Song,Lotte Vanheer,(unknown),Alexander Meissner,Kathrin Plath	32
11	Loss of MECP2 Leads to Activation of P53 and Neuronal Senescence 2018 ·Stem Cell Reports ·Minori Ohashi,(unknown),Denise E. Allen,Peiyee Lee,Kai Fu,(unknown),Jessica Cinkornpumin,Carlos E. Salas,(unknown),Igal Germanguz,Justin Langerman,Constantinos Chronis,Edward Kuoy,Stephen Tran,Xinshu Xiao,Matteo Pellegrini,Kathrin Plath,William E. Lowry	56
12	Mot1, Ino80C, and NC2 Function Coordinately to Regulate Pervasive Transcription in Yeast and Mammals 2017 ·Molecular Cell ·Yong Xue,Suman Pradhan,Fei Sun,Constantinos Chronis,Nancy Tran,Trent Su,Christopher Van,Ajay A. Vashisht,James A. Wohlschlegel,Craig L. Peterson,H. T. Marc Timmers,Siavash K. Kurdistani,Michael Carey	33
13	Cooperative Binding of Transcription Factors Orchestrates Reprogrammingbreakdown → 2017 ·Cell ·Constantinos Chronis,Petko Fiziev,Bernadett Papp,Stefan Butz,Giancarlo Bonora,Shan Sabri,Jason Ernst,Kathrin Plath	375
14	Human Naive Pluripotent Stem Cells Model X Chromosome Dampening and X Inactivation 2016 ·Cell stem cell ·Anna Sahakyan,Rachel Kim,Constantinos Chronis,Shan Sabri,Giancarlo Bonora,Thorold W. Theunissen,Edward Kuoy,Justin Langerman,Amander T. Clark,Rudolf Jaenisch,Kathrin Plath	163
15	Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency 2013 ·Nature Cell Biology ·Rupa Sridharan,Michelle Gonzales-Cope,Constantinos Chronis,Giancarlo Bonora,(unknown),Chengyang Huang,Sanjeet Patel,David Lopez,Nilamadhab Mishra,Matteo Pellegrini,Michael Carey,Benjamin A. García,Kathrin Plath	172
16	Long-Range Chromatin Contacts in Embryonic Stem Cells Reveal a Role for Pluripotency Factors and Polycomb Proteins in Genome Organization 2013 ·Cell stem cell ·Matthew Denholtz,Giancarlo Bonora,Constantinos Chronis,Erik Splinter,Wouter de Laat,Jason Ernst,Matteo Pellegrini,Kathrin Plath	204
17	Reducing MCM levels in human primary T cells during the G0→G1 transition causes genomic instability during the first cell cycle 2010 ·Oncogene ·(unknown),Terry J. Gaymes,(unknown),Constantinos Chronis,Barbara Czepulkowski,(unknown),G J Mufti,Edward M. Marcotte,N. Shaun B. Thomas	36
18	Mechanistic insights into reprogramming to induced pluripotency 2010 ·Journal of Cellular Physiology ·Ritchie Ho,Constantinos Chronis,Kathrin Plath	37
19	Epigenetics of human T cells during the G₀→G₁ transition 2009 ·Genome Research ·Alexander Smith,Constantinos Chronis,Manolis Christodoulakis,(unknown),Nicholas Lea,Natalie A. Twine,Akshay Bhinge,Ghulam J. Mufti,N. Shaun B. Thomas	17
20	CDKN2B methylation status and isolated chromosome 7 abnormalities predict responses to treatment with 5-azacytidine 2007 ·Leukemia ·Kavita Raj,(unknown),Aloysius Ho,Constantinos Chronis,Shahper N. Khan,(unknown),Sabine Pomplun,N S Thomas,G J Mufti	114

About Constantinos Chronis

Constantinos Chronis is a scholar working on Molecular Biology, Hematology and Biophysics, having authored 27 papers that have together received 1.9k indexed citations. Recurring topics across this work include CRISPR and Genetic Engineering (11 papers), Pluripotent Stem Cells Research (9 papers) and Epigenetics and DNA Methylation (8 papers). The work is most often cited by research in Molecular Biology (1.6k citations), Aging (31 citations) and Cancer Research (243 citations). Constantinos Chronis has collaborated with scholars based in United States, United Kingdom and Germany. Frequent co-authors include Kathrin Plath, Giancarlo Bonora, Jason Ernst, Shan Sabri, Bernadett Papp, Matteo Pellegrini, Hyunsoo Rho, Alexander R. Terry, Nissim Hay and Stefan Butz. Their work appears in journals such as Nature, Cell and Nucleic Acids Research.

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