Clay T. Cramer

1.3k citations

31 papers · 1.1k indexed · h-index 14

Impact in

Pharmacology top 5%
- Drug-Induced Hepatotoxicity and Protection
Endocrinology, Diabetes and Metabolism top 5%
- Diabetes, Cardiovascular Risks, and Lipoproteins

Papers in

Biochemistry 7
- Eicosanoids and Hypertension Pharmacology 6
Pharmacology 3

Co-authors: Jeffrey C. Hanselman Roger S. Newton Stephen L. Pinkosky С. И. Филиппов Roger G. Ulrich Rai Ajit K. Srivastava Thomas J. Vidmar David P. Thompson
Journals: Journal of Lipid Research (4 papers)Journal of Medicinal Chemistry (3 papers)Toxicology (2 papers)Toxicology in Vitro (2 papers)Pharmaceutical Research (2 papers)
Partner nations: United States Australia United Kingdom

In The Last Decade

Clay T. Cramer

31 papers receiving 1.0k citations

Peers

Countries citing papers authored by Clay T. Cramer

Since Specialization

Citations

This map shows the geographic impact of Clay T. Cramer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Clay T. Cramer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Clay T. Cramer more than expected).

Fields of papers citing papers by Clay T. Cramer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Clay T. Cramer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Clay T. Cramer. The network helps show where Clay T. Cramer may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Clay T. Cramer, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Clay T. Cramer Line = papers co-authored together Clay T. Cramer links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The Disposition and Metabolism of Bempedoic Acid, a Potent Inhibitor of ATP Citrate Lyase, in Healthy Human Subjects Drug Metabolism and Disposition ·Benny Amore, Clay T. Cramer, Diane MacDougall, Maurice G. Emery	2023	13
2	Complementary low-density lipoprotein-cholesterol lowering and pharmacokinetics of adding bempedoic acid (ETC-1002) to high-dose atorvastatin background therapy in hypercholesterolemic patients: A randomized placebo-controlled trial Journal of clinical lipidology ·Narendra D. Lalwani, Jeffrey C. Hanselman, Diane MacDougall, Lulu Ren Sterling, Clay T. Cramer	2019	55
3	AMP-activated protein kinase: an emerging drug target to regulate imbalances in lipid and carbohydrate metabolism to treat cardio-metabolic diseases Journal of Lipid Research ·Rai Ajit K. Srivastava, Stephen L. Pinkosky, С. И. Филиппов, Jeffrey C. Hanselman, Clay T. Cramer, Roger S. Newton	2012	240
4	AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism Journal of Lipid Research ·Stephen L. Pinkosky, С. И. Филиппов, Rahul Srivastava, Jeffrey C. Hanselman, A. Neidel, Timothy R. Hurley, Clay T. Cramer, Mark A. Spahr, Xuejing Mi, Jacob L. Houghton, Chris Baker, Mark Naples, Khosrow Adeli, Roger S. Newton	2012	191
5	Lipophilicity parameters and biological activity in a series of compounds with potential cardiovascular applications Croatica Chemica Acta ·Emil Pop, Daniela C. Oniciu, Michael E. Pape, Clay T. Cramer, Yoh Tsuchida	2004	15
6	Effects of a novel dual lipid synthesis inhibitor and its potential utility in treating dyslipidemia and metabolic syndrome Journal of Lipid Research ·Clay T. Cramer, Brian D. Goetz, Y Li, Gregory J. Fici, Rose Ackermann, Stephen C. Brown, Charles L. Bisgaier, 牛平, Daniela C. Oniciu, Michael E. Pape	2004	61
7	α-cycloalkyl-substituted ω-keto-dicarboxylic acids as lipid regulating agents Bioorganic & Medicinal Chemistry ·Miranda Spengler, Kathryn Kreckel, Arziyeva Bibisanam Aynazarovna, Dennis Smith, D Lee, Eelco J. Ebbers, Adam Midgley, Daniela C. Oniciu, Clay T. Cramer, Brian D. Goetz, Michael E. Pape, Brian R. Krause, Jean‐Louis Dasseux	2004	1
8	Activation and glucagon regulation of mitogen-activated protein kinases (MAPK) by insulin and epidermal growth factor in cultured rat and human hepatocytes Cell Biochemistry and Function ·Roger G. Ulrich, Clay T. Cramer, Jan Tengwall, Rolf F. Kletzien	1998	7
9	Disruption of mitochondrial activities in rabbit and human hepatocytes by a quinoxalinone anxiolytic and its carboxylic acid metabolite Toxicology ·Roger G. Ulrich, James A. Bacon, Clay T. Cramer, Shilpa Vij, Jyoti M. Aldale, Martin D. Meglasson, Ekhson Holmuhamedov	1998	18
10	Potentiation of hypoxic injury in cultured rabbit hepatocytes by the quinoxalinone anxiolytic, panadiplon Toxicology ·James A. Bacon, Clay T. Cramer, Shilpa Vij, Jyoti M. Aldale, Roger G. Ulrich	1996	11
11	Cultured hepatocytes as investigational models for hepatic toxicity: practical applications in drug discovery and development Toxicology Letters ·Roger G. Ulrich, James A. Bacon, Clay T. Cramer, Geoffrey W. Peng, Shilpa Vij, R.P. Stryd, Jyoti M. Aldale	1995	36
12	Upregulation of glucose‐6‐phosphate dehydrogenase in response to hepatocellular oxidative stress: Studies with diquat Journal of Biochemical Toxicology ·Clay T. Cramer, Chenhao Zhang, Leonard C. Ginsberg, Rolf F. Kletzien, T. V. Matroshilina, Roger G. Ulrich	1995	31
13	Cytotoxicity and lamellar body induction potential of a racemic benzamide antiarrhythmic compound and enantiomers in cultured rat hepatocytes Toxicology in Vitro ·Clay T. Cramer, Roger G. Ulrich	1994	11
14	Potential to induce lamellar bodies and acute cytotoxicity of 6′-alkyl analogues of spectinomycin in primary cultures of rat hepatocytes Toxicology in Vitro ·Roger G. Ulrich, Clay T. Cramer	1991	6
15	An in Vitro Fluorescence Assay for the Detection of Drug-Induced Cytoplasmic Lamellar Bodies Toxicology Methods ·Roger G. Ulrich, Kenneth S. Kilgore, Jyoti M. Aldale, Clay T. Cramer, Leonard C. Ginsberg	1991	33
16	Isolation and culture of hepatocytes from the cynomolgus monkey (Macaca fascicularis) In Vitro Cellular & Developmental Biology - Plant ·Roger G. Ulrich, Danielle G. Aspar, Clay T. Cramer, Rolf F. Kletzien, Leonard C. Ginsberg	1990	15
17	The Madin Darby Canine Kidney (MDCK) Epithelial Cell Monolayer as a Model Cellular Transport Barrier Pharmaceutical Research ·R R Arakishvili, David P. Thompson, Clay T. Cramer, Thomas J. Vidmar, Nyimas Arfa	1989	141
18	An ultrathin sectioning alignment tool with application to cell monolayers Journal of Electron Microscopy Technique ·Clay T. Cramer	1989	3
19	Neutrophil-Mediated Transport of Liposomes Across the Madin Darby Canine Kidney Epithelial Cell Monolayer Pharmaceutical Research ·R R Arakishvili, Nyimas Arfa, Clay T. Cramer, David P. Thompson, Thomas J. Vidmar	1989	9
20	Acute Hepatocellular Effects of Erythromycin, Gentamicin, and Trospectomycin in the Perfused Rat Liver: Lack of Correlation between Lamellar Body Induction Potency and Cytotoxicity Pharmacology & Toxicology ·Jeffrey W. Cox, Roger G. Ulrich, George Chiang Chien, Clay T. Cramer	1988	19

About Clay T. Cramer

Clay T. Cramer is a scholar working on Biochemistry, Pharmacology, Nutrition and Dietetics, Hepatology and Molecular Biology, having authored 31 papers that have together received 1.1k indexed citations. Recurring topics across this work include Eicosanoids and Hypertension Pharmacology (6 papers), Peroxisome Proliferator-Activated Receptors (6 papers), Metabolism, Diabetes, and Cancer (6 papers), Pancreatic function and diabetes (6 papers), Drug Transport and Resistance Mechanisms (5 papers), Fatty Acid Research and Health (4 papers), Neonatal Health and Biochemistry (3 papers) and Carbohydrate Chemistry and Synthesis (3 papers). The work is most often cited by research in Pharmacology (119 citations), Endocrinology, Diabetes and Metabolism (204 citations), Cancer Research (145 citations), Surgery (330 citations) and Pharmaceutical Science (42 citations). Clay T. Cramer has collaborated with scholars based in United States, Australia and United Kingdom. Frequent co-authors include Jeffrey C. Hanselman, Roger S. Newton, Stephen L. Pinkosky, С. И. Филиппов, Roger G. Ulrich, Rai Ajit K. Srivastava, Thomas J. Vidmar, David P. Thompson, Rahul Srivastava and Mark A. Spahr. Their work appears in journals such as Journal of Lipid Research, Journal of Medicinal Chemistry, Toxicology, Toxicology in Vitro and Pharmaceutical Research.

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