Christopher Walpole

2.1k citations

29 papers · 1.6k indexed · 1 hit paper · h-index 17

Impact in

Sensory Systems top 0.5%
- Ion Channels and Receptors
Toxicology top 2%
- Bioactive Compounds and Antitumor Agents

Papers in ⓘ

Toxicology 5
- Bioactive Compounds and Antitumor Agents 4
Sensory Systems 6
- Ion Channels and Receptors 6

Co-authors: Stuart Bevan (9 shared papers)Iain F. James (11 shared papers)Roger Wrigglesworth (12 shared papers)Glyn A. Hughes (4 shared papers)H P Rang (2 shared papers)J.C. Yeats (1 shared paper)Kirti Shah (1 shared paper)Sandeep S Hothi (1 shared paper)
Journals: Journal of Medicinal Chemistry (8 papers)Bioorganic & Medicinal Chemistry Letters (7 papers)British Journal of Pharmacology (3 papers)Neuroscience (2 papers)Tetrahedron (1 paper)
Partner nations: Canada Japan United Kingdom

In The Last Decade

Christopher Walpole

29 papers receiving 1.6k citations

Hit Papers

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Capsazepine: a competitive antagonist of the sensory neurone excitant capsaicin 1992 · 510 citations

Peers

Countries citing papers authored by Christopher Walpole

Since Specialization

Citations

This map shows the geographic impact of Christopher Walpole's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher Walpole with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher Walpole more than expected).

Fields of papers citing papers by Christopher Walpole

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher Walpole. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher Walpole. The network helps show where Christopher Walpole may publish in the future.

Co-authors

The 25 scholars most cited alongside Christopher Walpole, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Christopher Walpole Line = papers co-authored together Christopher Walpole links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 29 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Capsazepine: a competitive antagonist of the sensory neurone excitant capsaicin British Journal of Pharmacology ·Stuart Bevan, Sandeep S Hothi, Glyn A. Hughes, Iain F. James, H P Rang, Kirti Shah, Christopher Walpole, J.C. Yeats Hit paper breakdown →	1992	510
2	The Discovery of Capsazepine, the First Competitive Antagonist of the Sensory Neuron Excitants Capsaicin and Resiniferatoxin Journal of Medicinal Chemistry ·Christopher Walpole, Stuart Bevan, G. Bovermann, Johann J. Boelsterli, Robin J. Breckenridge, John W. Davies, Glyn A. Hughes, Iain F. James, Lukas Oberer, Janet Winter, Roger Wrigglesworth	1994	174
3	Analogs of capsaicin with agonist activity as novel analgesic agents; structure-activity studies. 1. The aromatic "A-region" Journal of Medicinal Chemistry ·Christopher Walpole, Roger Wrigglesworth, Stuart Bevan, Elizabeth A. Campbell, Andy Dray, Iain F. James, Martin Perkins, Derek J. Reid, Janet Winter	1993	133
4	Analogs of capsaicin with agonist activity as novel analgesic agents; structure-activity studies. 3. The hydrophobic side-chain "C-region" Journal of Medicinal Chemistry ·Christopher Walpole, Roger Wrigglesworth, Stuart Bevan, Elizabeth A. Campbell, Andy Dray, Iain F. James, Kay J. Masdin, Martin Perkins, Janet Winter	1993	82
5	A comparison of capsazepine and ruthenium red as capsaicin antagonists in the rat isolated urinary bladder and vas deferens British Journal of Pharmacology ·C.A. Maggi, Stuart Bevan, Christopher Walpole, H P Rang, Sandro Giuliani	1993	72
6	Similarities and Differences in the Structure−Activity Relationships of Capsaicin and Resiniferatoxin Analogues Journal of Medicinal Chemistry ·Christopher Walpole, Stuart Bevan, Graham C. Bloomfield, Robin J. Breckenridge, Iain F. James, Timothy J. Ritchie, A Szállaśi, Janet Winter, Roger Wrigglesworth	1996	71
7	Analogs of capsaicin with agonist activity as novel analgesic agents; structure-activity studies. 2. The amide bond "B-region" Journal of Medicinal Chemistry ·Christopher Walpole, Roger Wrigglesworth, Stuart Bevan, Elizabeth A. Campbell, Andy Dray, Iain F. James, Kay J. Masdin, Martin Perkins, Janet Winter	1993	70
8	2-Nitrophenylcarbamoyl-(S)-prolyl-(S)-3-(2-naphthyl)alanyl-N-benzyl-N- methylamide (SDZ NKT 343), a Potent Human NK₁ Tachykinin Receptor Antagonist with Good Oral Analgesic Activity in Chronic Pain Models Journal of Medicinal Chemistry ·Christopher Walpole, Sun Young Ko, Michael C. Brown, David T. Beattie, Elizabeth A. Campbell, F. Dickenson, SCOTT G. EWAN, Glyn A. Hughes, Marc Lemaire, Joanne Lerpiniere, S Patel, László Urbán	1998	57
9	New 1,2,3,4-tetrahydropyrrolo[3,4-b]indole derivatives as selective CB2 receptor agonists Bioorganic & Medicinal Chemistry Letters ·Daniel Pagé, Hua Yang, W. A. Brown, Christopher Walpole, Manon Fleurent, Meredith Fyfe, François Gaudreault, Stéphane St-Onge	2007	53
10	Analogues of Capsaicin with Agonist Activity as Novel Analgesic Agents: Structure−Activity Studies. 4. Potent, Orally Active Analgesics Journal of Medicinal Chemistry ·Roger Wrigglesworth, Christopher Walpole, Stuart Bevan, Elizabeth A. Campbell, Andy Dray, Glyn A. Hughes, Iain F. James, Kay J. Masdin, Janet Winter	1996	49
11	Characterization of resiniferatoxin binding sites on sensory neurons: Co-regulation of resiniferatoxin binding and capsaicin sensitivity in adult rat dorsal root ganglia Neuroscience ·J. Winter, Christopher Walpole, Stuart Bevan, Iain F. James	1993	45
12	NE-19550 and NE-21610, antinociceptive capsaicin analogues: studies on nociceptive fibres of the neonatal rat tail in vitro European Journal of Pharmacology ·A. Dray, J. Bettaney, A. Rueff, Christopher Walpole, Roger Wrigglesworth	1990	39
13	Selective neurokinin-1 receptor antagonists are anti-hyperalgesic in a model of neuropathic pain in the guinea-pig Neuroscience ·Elizabeth A. Campbell, Clive Gentry, S Patel, Moh Panesar, Christopher Walpole, László Urbán	1998	33
14	Long-lasting agonist activity produced by a capsaicin-like photoaffinity probe. Molecular Pharmacology ·Iain F. James, Christopher Walpole, Julie A. Hixon, J N Wood, Roger Wrigglesworth	1988	32
15	Discovery of P2X3 selective antagonists for the treatment of chronic pain Bioorganic & Medicinal Chemistry Letters ·Louis‐David Cantin, Malken Bayrakdarian, Christophe Buon, Eric Grazzini, Yun‐Jin Hu, Jean Labrecque, Carmen Leung, Xuehong Luo, Giovanni Martino, Michel Paré, Kemal Payza, Nirvana Popovic, Denis Projean, Vijayaratnam Santhakumar, Christopher Walpole, Yu Xiao, Mirosław J. Tomaszewski	2012	26
16	Discovery of μ-opioid selective ligands derived from 1-aminotetralin scaffolds made via metal-catalyzed ring-opening reactions Bioorganic & Medicinal Chemistry Letters ·Chris Dockendorff, Shujuan Jin, Madeline Olsen, Mark Lautens, Martin Coupal, Lejla Hodzic, Nathan Spear, Kemal Payza, Christopher Walpole, Mirosław J. Tomaszewski	2008	26
17	Immunochemical detection of photoaffinity‐labelled capsaicin‐binding proteins from sensory neurons FEBS Letters ·John N. Wood, Christopher Walpole, Iain F. James, Andy Dray, Paul R. Coote	1990	17
18	Enzyme inhibitors in medicine Natural Product Reports ·Christopher Walpole, Roger Wrigglesworth	1989	16
19	Comparative, general pharmacology of SDZ NKT 343, a novel, selective NK₁ receptor antagonist British Journal of Pharmacology ·Christopher Walpole, Michael C. Brown, Iain F. James, Elizabeth A. Campbell, Peter McIntyre, R J Docherty, Sun Young Ko, L. Hedley, SCOTT G. EWAN, K‐H Buchheit, László Urbán	1998	15
20	Capsaicin-like agonists Drugs of the Future ·Roger Wrigglesworth, Christopher Walpole	1998	15

About Christopher Walpole

Christopher Walpole is a scholar working on Toxicology, Sensory Systems, Cellular and Molecular Neuroscience, Physiology and Physiology, having authored 29 papers that have together received 1.6k indexed citations. Recurring topics across this work include Neuropeptides and Animal Physiology (9 papers), Pharmacological Receptor Mechanisms and Effects (8 papers), Pain Mechanisms and Treatments (7 papers), Ion Channels and Receptors (6 papers), Receptor Mechanisms and Signaling (5 papers), Cannabis and Cannabinoid Research (5 papers), Bioactive Compounds and Antitumor Agents (4 papers) and Chemical Synthesis and Analysis (3 papers). The work is most often cited by research in Sensory Systems (841 citations), Toxicology (108 citations), Cellular and Molecular Neuroscience (477 citations), Physiology (553 citations) and Complementary and alternative medicine (112 citations). Christopher Walpole has collaborated with scholars based in Canada, Japan and United Kingdom. Frequent co-authors include Stuart Bevan, Iain F. James, Roger Wrigglesworth, Glyn A. Hughes, H P Rang, J.C. Yeats, Kirti Shah, Sandeep S Hothi, Janet Winter and Andy Dray. Their work appears in journals such as Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, British Journal of Pharmacology, Neuroscience and Tetrahedron.

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