Timothy J. Ritchie

2.8k total citations · 1 hit paper
26 papers, 2.0k citations indexed

About

Timothy J. Ritchie is a scholar working on Organic Chemistry, Computational Theory and Mathematics and Pharmacology. According to data from OpenAlex, Timothy J. Ritchie has authored 26 papers receiving a total of 2.0k indexed citations (citations by other indexed papers that have themselves been cited), including 11 papers in Organic Chemistry, 11 papers in Computational Theory and Mathematics and 10 papers in Pharmacology. Recurrent topics in Timothy J. Ritchie's work include Computational Drug Discovery Methods (11 papers), Pharmacogenetics and Drug Metabolism (7 papers) and Analytical Chemistry and Chromatography (6 papers). Timothy J. Ritchie is often cited by papers focused on Computational Drug Discovery Methods (11 papers), Pharmacogenetics and Drug Metabolism (7 papers) and Analytical Chemistry and Chromatography (6 papers). Timothy J. Ritchie collaborates with scholars based in United Kingdom, Italy and Switzerland. Timothy J. Ritchie's co-authors include Simon J. F. Macdonald, Stephen D. Pickett, Robert J. Young, David Crich, Christopher N. Luscombe, Richard A. Lewis, Peter Ertl, Simon Peace, Roger Wrigglesworth and Graham C. Bloomfield and has published in prestigious journals such as Journal of Medicinal Chemistry, British Journal of Pharmacology and Tetrahedron.

In The Last Decade

Timothy J. Ritchie

26 papers receiving 1.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The impact of aromatic ring count on compound developability – are too many aromatic rings a liability in drug design?

2009 683 citations Timothy J. Ritchie, Simon J. F. Macdonald Drug Discovery Today profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Timothy J. Ritchie United Kingdom	18	1.1k	775	509	171	168	26	2.0k
Yvette M. Fobian United States	16	1.2k 1.1×	543 0.7×	419 0.8×	166 1.0×	185 1.1×	22	1.9k
Emanuele Carosati Italy	25	656 0.6×	1.1k 1.4×	542 1.1×	255 1.5×	177 1.1×	47	2.0k
Brian Springthorpe United Kingdom	5	546 0.5×	879 1.1×	589 1.2×	223 1.3×	179 1.1×	8	1.8k
Bruce D. Roth United States	30	1.4k 1.3×	906 1.2×	261 0.5×	118 0.7×	325 1.9×	61	2.6k
Jon A. Erickson United States	16	582 0.5×	621 0.8×	481 0.9×	146 0.9×	138 0.8×	31	1.5k
Anil K. Saxena India	29	1.3k 1.2×	933 1.2×	419 0.8×	111 0.6×	268 1.6×	146	2.8k
Jack Bikker United States	12	2.6k 2.4×	1.3k 1.6×	490 1.0×	151 0.9×	272 1.6×	18	3.8k
Roger B. Ruggeri United States	24	1.1k 1.0×	815 1.1×	134 0.3×	126 0.7×	126 0.8×	43	2.2k
Ozair Alam India	30	1.8k 1.6×	759 1.0×	266 0.5×	68 0.4×	294 1.8×	100	2.6k
Martin P. Edwards United States	15	492 0.4×	518 0.7×	286 0.6×	137 0.8×	149 0.9×	30	1.2k

Countries citing papers authored by Timothy J. Ritchie

Since Specialization

Citations

This map shows the geographic impact of Timothy J. Ritchie's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Timothy J. Ritchie with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Timothy J. Ritchie more than expected).

Fields of papers citing papers by Timothy J. Ritchie

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Timothy J. Ritchie. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Timothy J. Ritchie. The network helps show where Timothy J. Ritchie may publish in the future.

Co-authorship network of co-authors of Timothy J. Ritchie

This figure shows the co-authorship network connecting the top 25 collaborators of Timothy J. Ritchie. A scholar is included among the top collaborators of Timothy J. Ritchie based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Timothy J. Ritchie. Timothy J. Ritchie is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ritchie, Timothy J. & Simon J. F. Macdonald. (2016). Heterocyclic replacements for benzene: Maximising ADME benefits by considering individual ring isomers. European Journal of Medicinal Chemistry. 124. 1057–1068. 26 indexed citations

Ritchie, Timothy J. & Simon J. F. Macdonald. (2014). Physicochemical Descriptors of Aromatic Character and Their Use in Drug Discovery. Journal of Medicinal Chemistry. 57(17). 7206–7215. 81 indexed citations

Ritchie, Timothy J. & Simon J. F. Macdonald. (2014). How drug-like are ‘ugly’ drugs: do drug-likeness metrics predict ADME behaviour in humans?. Drug Discovery Today. 19(4). 489–495. 64 indexed citations

Ritchie, Timothy J., Simon J. F. Macdonald, Simon Peace, Stephen D. Pickett, & Christopher N. Luscombe. (2013). Increasing small molecule drug developability in sub-optimal chemical space. MedChemComm. 4(4). 673–673. 81 indexed citations

Ritchie, Timothy J. & Iain M. McLay. (2012). Should medicinal chemists do molecular modelling?. Drug Discovery Today. 17(11-12). 534–537. 15 indexed citations

Ritchie, Timothy J., Simon J. F. Macdonald, Simon Peace, Stephen D. Pickett, & Christopher N. Luscombe. (2012). The developability of heteroaromatic and heteroaliphatic rings – do some have a better pedigree as potential drug molecules than others?. MedChemComm. 3(9). 1062–1062. 144 indexed citations

Ritchie, Timothy J., Simon J. F. Macdonald, Robert J. Young, & Stephen D. Pickett. (2010). The impact of aromatic ring count on compound developability: further insights by examining carbo- and hetero-aromatic and -aliphatic ring types. Drug Discovery Today. 16(3-4). 164–171. 339 indexed citations

Ritchie, Timothy J., Peter Ertl, & Richard A. Lewis. (2010). The graphical representation of ADME-related molecule properties for medicinal chemists. Drug Discovery Today. 16(1-2). 65–72. 166 indexed citations

Ritchie, Timothy J. & Simon J. F. Macdonald. (2009). The impact of aromatic ring count on compound developability – are too many aromatic rings a liability in drug design?. Drug Discovery Today. 14(21-22). 1011–1020. 683 indexed citations breakdown →

10.

Fox, Alyson, Satbir Kaur, Bifang Li, et al.. (2005). Antihyperalgesic activity of a novel nonpeptide bradykinin B₁ receptor antagonist in transgenic mice expressing the human B₁ receptor. British Journal of Pharmacology. 144(7). 889–899. 32 indexed citations

11.

Ritchie, Timothy J.. (2001). Chemoinformatics: manipulating chemical information to facilitate decision-making in drug discovery. Drug Discovery Today. 6(16). 813–814. 3 indexed citations

12.

Bloomfield, Graham C., Timothy J. Ritchie, & Roger Wrigglesworth. (1992). Synthesis of 2,9,10-trioxatricyclo[4.3.1.0]decane analogues of resiniferatoxin. Journal of the Chemical Society Perkin Transactions 1. 1229–1229. 8 indexed citations

13.

Bloomfield, Graham C., Roger Wrigglesworth, & Timothy J. Ritchie. (1991). The stereoselective synthesis of 2,9,10-trioxatricyclo[4.3.1.0]decane analogues of resiniferatoxin. Journal of the Chemical Society Chemical Communications. 215–215. 2 indexed citations

14.

Crich, David & Timothy J. Ritchie. (1990). Silyl migration and formation of an anhydro derivative on attempted benzylation of 3-O-tert-butyldimethylsilyl-6-O-tosyl-d-glucal. Carbohydrate Research. 197. 324–326. 10 indexed citations

15.

Crich, David, et al.. (1990). Acyl radical cyclizations in synthesis. part 2 further substituent effects on the mode and efficiency of cyclizaion of 6-heptenoyl radicals.. Tetrahedron. 46(6). 2135–2148. 28 indexed citations

16.

Crich, David & Timothy J. Ritchie. (1989). Preparation of 2-deoxy-β-d-lyxo-hexosides (2-deoxy-β-d-galactosides). Carbohydrate Research. 190(1). C3–C6. 32 indexed citations

17.

Crich, David, et al.. (1989). Carbonyl Radical Cyclizations: Preparation of Some Heterocyclic Ketones. Heterocycles. 28(1). 67–67. 15 indexed citations

18.

Crich, David & Timothy J. Ritchie. (1988). Stereoselective free radical reactions in the preparation of 2-deoxy-β-D-glucosides. Journal of the Chemical Society Chemical Communications. 0(22). 1461–1463. 52 indexed citations

19.

Crich, David & Timothy J. Ritchie. (1988). Preparation and reactions of some cyclic orthoester derivatives. Tetrahedron. 44(8). 2319–2328. 19 indexed citations

20.

Ayres, D. C. & Timothy J. Ritchie. (1988). Lignans and related phenols. Part 18. The synthesis of quinones from podophyllotoxin and its analogues. Journal of the Chemical Society Perkin Transactions 1. 2573–2573. 7 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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