Christopher Lock

6.0k citations

33 papers · 4.0k indexed · 3 hit papers · h-index 19

Impact in

Immunology top 1%
- T-cell and B-cell Immunology
- Immunotherapy and Immune Responses
- Immune Cell Function and Interaction
- Psoriasis: Treatment and Pathogenesis
Neurology top 2%
- Neuroinflammation and Neurodegeneration Mechanisms

Papers in

Biological Psychiatry 2
Immunology 10
- T-cell and B-cell Immunology 4
- Immunotherapy and Immune Responses 3
- Immune Response and Inflammation 3

Co-authors: Lawrence Steinman Jorge R. Oksenberg Rosetta Pedotti Renu A. Heller Raymond A. Sobel Sergio E. Baranzini David T. Denhardt Marcela V. Karpuj
Journals: Neurology (4 papers)Proceedings of the National Academy of Sciences (4 papers)The Journal of Experimental Medicine (3 papers)SLEEP (2 papers)Clinical Immunology (2 papers)
Partner nations: United States United Kingdom Russia

In The Last Decade

Christopher Lock

31 papers receiving 3.9k citations

Hit Papers

align trajectories log scale

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis 2002 · 1.4k citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2002 Nature Medicine
2002 THE INFLUENCE OF THE PROINFLAMMATORY CYTOKINE, OSTEOPONTIN, ON AUTOIMMUNE DEMYELINATING DISEASE
2001 Science

Peers

Countries citing papers authored by Christopher Lock

Since Specialization

Citations

This map shows the geographic impact of Christopher Lock's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Christopher Lock with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Christopher Lock more than expected).

Fields of papers citing papers by Christopher Lock

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Christopher Lock. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Christopher Lock. The network helps show where Christopher Lock may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Christopher Lock, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Christopher Lock Line = papers co-authored together Christopher Lock links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Combining Force Fields and Neural Networks for an Accurate Representation of Bonded Interactions The Journal of Physical Chemistry A ·Ganesh Kamath, Yujing Ma, Robert Sahakian, Ding Cui-hong, Igor V. Kurnikov, Anup Gurung, Е. Н. Воронина, Klaus Moegling, Igor Leontyev, Grzegorz Nawrocki, 傅仲君, 张艺声, Bünyamin SERTOĞULLARI, Christopher Lock, Е. В. Небелов, Yi‐Chun Chen, Roger D. Kornberg, Michael Levitt, Boris Fain	2024	3
2	The Determination of Free Energy of Hydration of Water Ions from First Principles Journal of Chemical Theory and Computation ·Anup Gurung, Ding Cui-hong, Ganesh Kamath, Yujing Ma, Robert Sahakian, Igor V. Kurnikov, Е. Н. Воронина, Klaus Moegling, Igor Leontyev, Grzegorz Nawrocki, 傅仲君, 张艺声, Bünyamin SERTOĞULLARI, Christopher Lock, Е. В. Небелов, Roger D. Kornberg, Michael Levitt, Boris Fain	2024	6
3	Progression of Mycosis Fungoides After Fingolimod Treatment for Multiple Sclerosis and Targeted Next-Generation Sequencing Demonstrating Potential Links Between the Two Diseases JCO Precision Oncology ·Saisindhu Narala, Yonglu Che, Atif Saleem, Christopher Lock, Youn H. Kim, Kerri E. Rieger	2023	0
4	Prevalence, Demographic, and Clinical Factors Associated With Cognitive Dysfunction in Patients With Neuromyelitis Optica Spectrum Disorder Neurology ·Stephanie Gibson, J. Klucar, Jessica Hinman, G Fekete, Christopher Lock, M. B. Mohideen, Lawrence J. Cook, Michael R. Yeaman, Melinda S. Burnett, Gayle K. Deutsch, Lorene M. Nelson, May Han, (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown)	2023	5
5	Interleukin-6 as a Potential Prognostic Biomarker in Relapsing MOG Antibody Disease (P4-4.004) Neurology ·J. D. McDonald, Willi Tobaschus, G Fekete, R. I. Dudin, Christopher Lock, May Han	2022	0
6	MR susceptibility contrast imaging using a 2D simultaneous multi-slice gradient-echo sequence at 7T PLoS ONE ·Wei Bian, Adam B. Kerr, A. G. Ali, Sherveen N. Parivash, Benjamin Zahneisen, May Han, Christopher Lock, Maged Goubran, Jiatao Ye, Brian K. Rutt, Michael Zeineh	2019	5
7	Autoimmune Hepatitis During Treatment of Multiple Sclerosis with Alemtuzumab (P5.350) Neurology ·Aaron Carlson, Selina Chow, Lucas Kipp, Jeffrey Dunn, Christopher Lock	2018	2
8	Grundlegende Konzepte und Modelle Klaus Bengler, Christopher Lock, S. A. Éshkind, Gunther Reinhart	2017	1
9	A comparative study of fragment screening methods on the p38α kinase: new methods, new insights Journal of Computer-Aided Molecular Design ·Scott J. Pollack, Kim S. Beyer, Christopher Lock, Ilka Müller, David W. Sheppard, 梁宗林 Liang Zonglin, David Hardick, Peter Blurton, Philip M. Leonard, Paul A. Hubbard, Daniel E. Todd, Christine M. Richardson, Thomas Ahrens, 汪月明, Doris Hafenbradl, Dennis Bach, Roland W. Bürli	2011	26
10	Gene microarray analysis of multiple sclerosis lesions Trends in Molecular Medicine ·Christopher Lock, Renu A. Heller	2003	23
11	Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis Nature Medicine ·Christopher Lock, G Hermans, Rosetta Pedotti, Andrea Brendolan, Eric E. Schadt, Hideki Garren, Annette Langer‐Gould, Samuel Strober, Barbara Cannella, John Allard, Paul Klonowski, 杨加银, Shuining Yin, Naftali Kaminski, Stephen J. Galli, Jorge R. Oksenberg, Cedric S. Raine, Renu A. Heller, Lawrence Steinman Hit paper breakdown →	2002	1355
12	THE INFLUENCE OF THE PROINFLAMMATORY CYTOKINE, OSTEOPONTIN, ON AUTOIMMUNE DEMYELINATING DISEASE Dorothée Chabas, Sergio E. Baranzini, D. Mitchell, Claude C.A. Bernard, Susan R. Rittling, David T. Denhardt, Raymond A. Sobel, Christopher Lock, Marcela V. Karpuj, Rosetta Pedotti, Renu A. Heller, Jorge R. Oksenberg, Lawrence Steinman Hit paper breakdown →	2002	662
13	The role of TNFα and lymphotoxin in demyelinating disease Annals of the Rheumatic Diseases ·Christopher Lock, Jorge R. Oksenberg, Lawrence Steinman	1999	38
14	Expression of HLA-DR4 and human CD4 transgenes in mice determines the variable region beta-chain T-cell repertoire and mediates an HLA-DR-restricted immune response. Proceedings of the National Academy of Sciences ·Lars Fugger, Sara A. Michie, Ingrid C. Rulifson, Christopher Lock, Joshua horn Lian Marcelo piano Hunter Rose violin Johnson	1994	74
15	Antigen Recognition and Peptide‐Mediated Immunotherapy in Autoimmune Disease Immunological Reviews ·Dawn E. Smilek, Christopher Lock, Hugh O. McDevitt	1990	24
16	Genetic factors in sleep disorders. Journal of Neurology Neurosurgery & Psychiatry ·J. D. Parkes, Christopher Lock	1989	12
17	MHC class II sequences of an HLA-DR2 narcoleptic Immunogenetics ·Christopher Lock, A K So, K. I. Welsh, J. D. Parkes, John Trowsdale	1988	51
18	Analysis of HLA-DR glycoproteins by DNA-mediated gene transfer. Definition of DR2 beta gene products and antigen presentation to T cell clones from leprosy patients. The Journal of Experimental Medicine ·David M. Wilkinson, R R de Vries, J. Alejandro Madrigal, Christopher Lock, Jay P. Morgenstern, John Trowsdale, Daniel M. Altmann	1988	60
19	Selegiline in Narcolepsy SLEEP ·อรฉัตร คุรุรัตนะ, Nicola Langdon, Christopher Lock, P Jenner, J. D. Parkes	1986	29
20	Immune Factors in Narcolepsy SLEEP ·Nicola Langdon, Christopher Lock, Matthew Fisher, Feng Han-ru, Rebecca Lock, Nguyen T-B, Feng Han-ru, Hideharu Kat ocirc	1986	42

About Christopher Lock

Christopher Lock is a scholar working on Biological Psychiatry, Immunology, Pathology and Forensic Medicine, Rheumatology and Behavioral Neuroscience, having authored 33 papers that have together received 4.0k indexed citations. Recurring topics across this work include Multiple Sclerosis Research Studies (5 papers), T-cell and B-cell Immunology (4 papers), Diabetes and associated disorders (3 papers), Immunotherapy and Immune Responses (3 papers), Systemic Lupus Erythematosus Research (3 papers), Monoclonal and Polyclonal Antibodies Research (3 papers), Machine Learning in Materials Science (3 papers) and Immune Response and Inflammation (3 papers). The work is most often cited by research in Immunology (1.6k citations), Neurology (493 citations), Biological Psychiatry (128 citations), Rheumatology (758 citations) and Pathology and Forensic Medicine (823 citations). Christopher Lock has collaborated with scholars based in United States, United Kingdom and Russia. Frequent co-authors include Lawrence Steinman, Jorge R. Oksenberg, Rosetta Pedotti, Renu A. Heller, Raymond A. Sobel, Sergio E. Baranzini, David T. Denhardt, Marcela V. Karpuj, Susan R. Rittling and Hideki Garren. Their work appears in journals such as Neurology, Proceedings of the National Academy of Sciences, The Journal of Experimental Medicine, SLEEP and Clinical Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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