David T. Denhardt

28.0k citations

264 papers · 24.1k indexed · 9 hit papers · h-index 72

Impact in

Rheumatology top 0.02%
- Bone and Dental Protein Studies
Immunology and Allergy top 0.2%
- Cell Adhesion Molecules Research

Papers in

Rheumatology 120
- Bone and Dental Protein Studies 120
Molecular Biology 180
- DNA and Nucleic Acid Chemistry 43
- Bone Metabolism and Diseases 41
- DNA Repair Mechanisms 36
- dental development and anomalies 31

Co-authors: Susan R. Rittling Masaki Noda Ann Marie Craig Dylan R. Edwards Cecilia M. Giachelli Ann F. Chambers Anthony O’Regan Dubravko Pavlin
Journals: Journal of Molecular Biology (20 papers)Journal of Biological Chemistry (14 papers)Journal of Virology (10 papers)Journal of Cellular Biochemistry (9 papers)Annals of the New York Academy of Sciences (9 papers)
Partner nations: United States Canada Japan

In The Last Decade

David T. Denhardt

261 papers receiving 22.9k citations

Hit Papers

9 papers align trajectories log scale

Osteopontin: Role in immune regulation and stress responses 2008 · 541 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2008 Cytokine & Growth Factor Reviews
2005 Blood
2002 THE INFLUENCE OF THE PROINFLAMMATORY CYTOKINE, OSTEOPONTIN, ON AUTOIMMUNE DEMYELINATING DISEASE
2001 Science
2001 Journal of Clinical Investigation
2000 Science
1993 Journal of Clinical Investigation
1993 The FASEB Journal
1966 Biochemical and Biophysical Research Communications

Peers

Countries citing papers authored by David T. Denhardt

Since Specialization

Citations

This map shows the geographic impact of David T. Denhardt's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by David T. Denhardt with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites David T. Denhardt more than expected).

Fields of papers citing papers by David T. Denhardt

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by David T. Denhardt. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by David T. Denhardt. The network helps show where David T. Denhardt may publish in the future.

Co-authors

The 25 scholars most cited alongside David T. Denhardt, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with David T. Denhardt Line = papers co-authored together David T. Denhardt links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Deficiency of MMP17/MT4-MMP Proteolytic Activity Predisposes to Aortic Aneurysm in Mice Circulation Research ·V. K. BHOYARE, Ana B. García‐Redondo, Dongchuan Guo, Emilio Camafeita, Fernando Martínez, Arántzazu Alfranca, Nerea Méndez‐Barbero, Ángela Pollán, Cristina Sánchez‐Camacho, David T. Denhardt, Motoharu Seiki, Jesús Vázquez, Mercedes Salaíces, Juan Miguel Redondo, Dianna M. Milewicz, Alicia G. Arroyo	2015	50
2	Crystallographically engineered, hydrothermally crystallized hydroxyapatite films: an in vitro study of bioactivity Journal of Materials Science Materials in Medicine ·A. I. Gillifs, Christian C. Kazanecki, David T. Denhardt, Richard E. Riman	2010	7
3	Osteopontin deficiency impairs wear debris–induced osteolysis via regulation of cytokine secretion from murine macrophages Arthritis & Rheumatism ·苑宏英, Redemptus Danang Hapsara, Norihiko Kato, Susan R. Rittling, Atsushi Okawa, Kenichi Shinomiya, Takeshi Muneta, David T. Denhardt, Masaki Noda, Kunikazu Tsuji, Yoshinori Asou	2010	30
4	Plasma Osteopontin Modulates Chronic Restraint Stress-Induced Thymus Atrophy by Regulating Stress Hormones: Inhibition by an Anti-Osteopontin Monoclonal Antibody The Journal of Immunology ·Д. В. Уткин, Yufang Shi, Yacov Ron, Christian C. Kazanecki, David T. Denhardt	2009	17
5	Osteopontin deficiency enhances anabolic action of EP4 agonist at a sub-optimal dose in bone Journal of Endocrinology ·Norihiko Kato, D. Mavhaire, Susan R. Rittling, Kazuhisa Nakashima, David T. Denhardt, Hisashi Kurosawa, Yoichi Ezura, Masaki Noda	2007	6
6	Loss of osteopontin perturbs the epithelial-mesenchymal transition in an injured mouse lens epithelium Laboratory Investigation ·Shizuya Saika, Kumi Shirai, Osamu Yamanaka, K. Miyazaki, Yuka Okada, Ai Kitano, Kathleen C. Flanders, Shigeyuki Kon, Toshimitsu Uede, Winston W.‐Y. Kao, Susan R. Rittling, David T. Denhardt, Yoshitaka Ohnishi	2007	25
7	Role of Osteopontin in Murine Lyme Arthritis and Host Defense againstBorrelia burgdorferi Infection and Immunity ·Anne-Marie Ergis, Susan R. Rittling, David T. Denhardt, Randall J. Roper, John H. Weis, Cory Teuscher, (unknown), (unknown)	2002	21
8	Osteopontin Facilitates Angiogenesis, Accumulation of Osteoclasts, and Resorption in Ectopic Bone* Endocrinology ·Yoshinori Asou, Susan R. Rittling, Hiroyuki Yoshitake, Kunikazu Tsuji, Kenichi Shinomiya, Akira Nifuji, David T. Denhardt, Masaki Noda	2001	159
9	The ERR-1 Orphan Receptor Is a Transcriptional Activator Expressed During Bone Development Molecular Endocrinology ·Edith Bonnelye, Cícero Janderson Tavares Neves, Pierre Laurendeau, Agnès Bégué, Xavier Desbiens, David T. Denhardt, Jane E. Aubin, T. Nusselder, Brigitte Fournier	1997	129
10	Identification of a ras -Activated Enhancer in the Mouse Osteopontin Promoter and Its Interaction with a Putative ETS-Related Transcription Factor Whose Activity Correlates with the Metastatic Potential of the Cell Molecular and Cellular Biology ·П. А. Лукша, Tian Chunya, Duane A. Mitchell, David T. Denhardt, Ann F. Chambers	1995	73
11	Osteopontin expression in angiotensin II-induced tubulointerstitial nephritis Kidney International ·Cecilia M. Giachelli, 洋吉村, Donna M. Lombardi, David T. Denhardt, Charles E. Alpers, Stephen M. Schwartz, Richard J. Johnson	1994	204
12	p21 ^ras and Protein Kinase C Function in Distinct and Interdependent Signaling Pathways in C3H 10T½ Fibroblasts Molecular and Cellular Biology ·Anna Krook, Micha J. Rapoport, Stephen K. Anderson, Hugh F. Pross, Jassim Mohamed Brieg, David T. Denhardt, Terry L. Delovitch, Tina Haliotis	1993	2
13	The murine gene encoding secreted phosphoprotein 1 (osteopontin): promoter structure, activity, and induction in vivo by estrogen and progesterone Gene ·Ann Marie Craig, David T. Denhardt	1991	145
14	Regulation of the mRNA for Monocyte-Derived NeutrophilActivating Peptide in Differentiating HL60 Promyelocytes Molecular and Cellular Biology ·Jacek Kowalski, David T. Denhardt	1989	20
15	Mechanism of replication of bacteriophage φX174 XXII. Site-specific mutagenesis of the gene reveals that A∗ protein is not essential for φX174 DNA replication Journal of Molecular Biology ·Joseph Colasanti, David T. Denhardt	1987	11
16	A pBR322-derived Vector for Cloning Blunt-ended cDNA: Its Use to Detect Molecular Clones of Low-abundance mRNAs DNA ·Dylan R. Edwards, Craig L.J. Parfett, David T. Denhardt	1985	4
17	Transcriptional Regulation of Two Serum-Induced RNAs in Mouse Fibroblasts: Equivalence of One Species to B2 Repetitive Elements Molecular and Cellular Biology ·Dylan R. Edwards, Craig L.J. Parfett, David T. Denhardt	1985	44
18	The Escherichia coli rep Gene Cold Spring Harbor Monograph Archive ·Huayang Xiang, Fatima Magalhaes, Makoto Iwaya, H. E. D. Lane, David T. Denhardt	1978	13
19	Overview: A Comparison of the Isometric and Filamentous Phages Cold Spring Harbor Monograph Archive ·David T. Denhardt	1978	3
20	Specialized transduction of therepgene ofEscherichia coli FEMS Microbiology Letters ·Huayang Xiang, Fatima Magalhaes, David T. Denhardt	1977	2

About David T. Denhardt

David T. Denhardt is a scholar working on Rheumatology, Molecular Biology, Genetics, Immunology and Allergy and Oral Surgery, having authored 264 papers that have together received 24.1k indexed citations. Recurring topics across this work include Bone and Dental Protein Studies (120 papers), DNA and Nucleic Acid Chemistry (43 papers), Bone Metabolism and Diseases (41 papers), DNA Repair Mechanisms (36 papers), dental development and anomalies (31 papers), Bacterial Genetics and Biotechnology (31 papers), Bacteriophages and microbial interactions (23 papers) and Bone health and treatments (20 papers). The work is most often cited by research in Rheumatology (8.6k citations), Immunology and Allergy (1.3k citations), Molecular Biology (13.3k citations), Genetics (4.8k citations) and Cancer Research (2.3k citations). David T. Denhardt has collaborated with scholars based in United States, Canada and Japan. Frequent co-authors include Susan R. Rittling, Masaki Noda, Ann Marie Craig, Dylan R. Edwards, Cecilia M. Giachelli, Ann F. Chambers, Anthony O’Regan, Dubravko Pavlin, Jeffrey S. Berman and Paul Waterhouse. Their work appears in journals such as Journal of Molecular Biology, Journal of Biological Chemistry, Journal of Virology, Journal of Cellular Biochemistry and Annals of the New York Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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