Chengkai Dai

4.8k citations

31 papers · 3.6k indexed · 3 hit papers · h-index 23

Impact in

Aging top 1%
Genetics top 0.5%
- Glioma Diagnosis and Treatment

Papers in

Aging 6
- Genetics, Aging, and Longevity in Model Organisms 6
Cell Biology 14
- Endoplasmic Reticulum Stress and Disease 13

Co-authors: Eric C. Holland Gregory N. Fuller Joseph Celestino Luke Whitesell Susan Lindquist Arlin B. Rogers Laura Schaefer Raymond Sawaya
Journals: Neoplasia (2 papers)Cell (2 papers)Genes & Development (2 papers)Oncogene (2 papers)Nature Genetics (1 paper)
Partner nations: United States China France

In The Last Decade

Chengkai Dai

31 papers receiving 3.6k citations

Hit Papers

align trajectories log scale

Heat Shock Factor 1 Is a Powerful Multifaceted Modifier of Carcinogenesis 2007 · 657 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2007 Cell
2001 Genes & Development
2000 Nature Genetics

Peers

Countries citing papers authored by Chengkai Dai

Since Specialization

Citations

This map shows the geographic impact of Chengkai Dai's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Chengkai Dai with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Chengkai Dai more than expected).

Fields of papers citing papers by Chengkai Dai

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Chengkai Dai. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Chengkai Dai. The network helps show where Chengkai Dai may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Chengkai Dai, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Chengkai Dai Line = papers co-authored together Chengkai Dai links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Heat shock factor 1 (HSF1) specifically potentiates c-MYC-mediated transcription independently of the canonical heat shock response Cell Reports ·Meng Xu, Ling Lin, A.F. Adebowale, Omprakash Shriwas, Tucker Edmonds, Siyuan Dai, Kuo‐Hui Su, Zijian Tang, Chengkai Dai	2023	7
2	Detection of the DNA binding of transcription factors in situ at the single-cell resolution in cultured cells by proximity ligation assay STAR Protocols ·A.F. Adebowale, Chengkai Dai	2023	1
3	Heat shock factor 1 is a direct anti-amyloid factor: connecting neurodegeneration and uncontrolled growth Neural Regeneration Research ·Chengkai Dai, Zijian Tang	2021	2
4	Heat Shock Factor 1 Is a Direct Antagonist of AMP-Activated Protein Kinase Molecular Cell ·Kuo‐Hui Su, Siyuan Dai, Zijian Tang, Meng Xu, Chengkai Dai	2019	32
5	The heat-shock, or HSF1-mediated proteotoxic stress, response in cancer: from proteomic stability to oncogenesis Philosophical Transactions of the Royal Society B Biological Sciences ·Chengkai Dai	2017	89
6	Visualization of RAS/MAPK Signaling In Situ by the Proximity Ligation Assay (PLA) Methods in molecular biology ·Zijian Tang, Chengkai Dai	2016	1
7	Negative regulation of the p300-p53 interplay by DDX24 Oncogene ·Deshun Shi, Chengkai Dai, Jun Qin, Wei Gu	2015	35
8	MEK Guards Proteome Stability and Inhibits Tumor-Suppressive Amyloidogenesis via HSF1 Cell ·Zijian Tang, Siyuan Dai, Di Kota Bogor, Rosalinda Doty, Leonard D. Shultz, Stephen B. Sampson, Chengkai Dai	2015	126
9	Suppression of the HSF 1‐mediated proteotoxic stress response by the metabolic stress sensor AMPK The EMBO Journal ·Siyuan Dai, Zijian Tang, Junyue Cao, Wei Zhou, Huawen Li, Stephen B. Sampson, Chengkai Dai	2014	78
10	Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis Journal of Clinical Investigation ·Chengkai Dai, Sandro Santagata, Zijian Tang, Jiayuan Shi, Junxia Cao, Markus Tümpel, Roderick T. Bronson, Luke Whitesell, Susan Lindquist	2012	104
11	Sulforaphane Activates Heat Shock Response and Enhances Proteasome Activity through Up-regulation of Hsp27 Journal of Biological Chemistry ·Nanqin Gan, Yu‐Chieh Wu, Mathilde Brunet, Carmen Garrido, Fung‐Lung Chung, Chengkai Dai, Lixin Mi	2010	102
12	Peptidyl-prolyl cis/trans isomerase Pin1 is critical for the regulation of PKB/Akt stability and activation phosphorylation Oncogene ·Yong Liao, Yan Ke, Xiaofei Zhou, Jinling Yang, Chengkai Dai, Katie Atalla, Nitin Agarwal, Dos D. Sarbassov, Da Shi, Dihua Yu, Mien‐Chie Hung	2009	77
13	Heat Shock Factor 1 Is a Powerful Multifaceted Modifier of Carcinogenesis Cell ·Chengkai Dai, Luke Whitesell, Arlin B. Rogers, Susan Lindquist Hit paper breakdown →	2007	657
14	The Characteristics of Astrocytomas and Oligodendrogliomas Are Caused by Two Distinct and Interchangeable Signaling Formats Neoplasia ·Chengkai Dai, Andi Nurningsih Gunawan, Alan H. Shih, Xiaoyi Hu, Gregory N. Fuller, Marc K. Rosenblum, Eric C. Holland	2005	42
15	Astrocyte Differentiation States and Glioma Formation The Cancer Journal ·Chengkai Dai, Eric C. Holland	2003	35
16	MYC Expression Promotes the Proliferation of Neural Progenitor Cells in Culture and In Vivo Neoplasia ·Dan Fults, Carolyn A. Pedone, Chengkai Dai, Eric C. Holland	2002	53
17	PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo Genes & Development ·Chengkai Dai, Joseph Celestino, Yoshifumi Okada, David N. Louis, Gregory N. Fuller, Eric C. Holland Hit paper breakdown →	2001	546
18	Glioma models Biochimica et Biophysica Acta (BBA) - Reviews on Cancer ·Chengkai Dai, Eric C. Holland	2001	22
19	Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice Nature Genetics ·Eric C. Holland, Joseph Celestino, Chengkai Dai, Laura Schaefer, Raymond Sawaya, Gregory N. Fuller Hit paper breakdown →	2000	705
20	Astrocytes Give Rise to Oligodendrogliomas and Astrocytomas after Gene Transfer of Polyoma Virus Middle T Antigen in Vivo American Journal Of Pathology ·Eric C. Holland, Yi Li, Joseph Celestino, Chengkai Dai, Laura Schaefer, Raymond Sawaya, Gregory N. Fuller	2000	65

About Chengkai Dai

Chengkai Dai is a scholar working on Aging, Cell Biology, Genetics, Molecular Biology and Developmental Neuroscience, having authored 31 papers that have together received 3.6k indexed citations. Recurring topics across this work include Endoplasmic Reticulum Stress and Disease (13 papers), Heat shock proteins research (12 papers), Glioma Diagnosis and Treatment (7 papers), Genetics, Aging, and Longevity in Model Organisms (6 papers), interferon and immune responses (4 papers), Signaling Pathways in Disease (3 papers), Cancer Mechanisms and Therapy (2 papers) and Epigenetics and DNA Methylation (2 papers). The work is most often cited by research in Aging (170 citations), Genetics (1.0k citations), Developmental Neuroscience (324 citations), Cancer Research (667 citations) and Cell Biology (721 citations). Chengkai Dai has collaborated with scholars based in United States, China and France. Frequent co-authors include Eric C. Holland, Gregory N. Fuller, Joseph Celestino, Luke Whitesell, Susan Lindquist, Arlin B. Rogers, Laura Schaefer, Raymond Sawaya, Stephen B. Sampson and David N. Louis. Their work appears in journals such as Neoplasia, Cell, Genes & Development, Oncogene and Nature Genetics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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