Caroline Le Guiner

2.7k citations

47 papers · 1.6k indexed · h-index 20

Genetics top 5%
- Virus-based gene therapy research 25
Molecular Biology top 5%
- Muscle Physiology and Disorders 20
- RNA Interference and Gene Delivery 13
- CRISPR and Genetic Engineering 7
- RNA Research and Splicing 6
Aging top 10%
Cellular and Molecular Neuroscience top 10%
Genetics top 10%
- Virus-based gene therapy research 25
Surgery
- Tissue Engineering and Regenerative Medicine 4
Cardiology and Cardiovascular Medicine
- Cardiomyopathy and Myosin Studies 4
Oncology
- CAR-T cell therapy research 3

Co-authors: Philippe Moullier Richard O. Snyder Fabienne Rolling Richard Breathnach Fabienne Del Gatto–Konczak Yan Chérel Magalie Penaud‐Budloo Liliane Kister
Cited by: Genetics Molecular Biology Aging
Journals: Journal of Biological Chemistry (3 papers)Nature Communications (1 paper)PLoS ONE (5 papers)
Partner nations: France United States United Kingdom

In The Last Decade

Caroline Le Guiner

44 papers receiving 1.6k citations

Peers

Countries citing papers authored by Caroline Le Guiner

Since Specialization

Citations

This map shows the geographic impact of Caroline Le Guiner's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Caroline Le Guiner with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Caroline Le Guiner more than expected).

Fields of papers citing papers by Caroline Le Guiner

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Caroline Le Guiner. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Caroline Le Guiner. The network helps show where Caroline Le Guiner may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Caroline Le Guiner, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Caroline Le Guiner Line = papers co-authored together Caroline Le Guiner links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Transcriptomic profiling of skeletal muscle in the DMDmdx rat model of Duchenne muscular dystrophy Scientific Reports ·Abdolvahab Ebrahimpour Gorji,Katarzyna Kliczkowska,Marcin Ollik,Caroline Le Guiner,Jacek Wilczak,Wojciech Bielecki,Piotr Ostaszewski,Masoud Shirali,Zahra Roudbari,Tomasz Sadkowski	2025	0
2	Dystrophin deficiency impairs cell junction formation during embryonic myogenesis from pluripotent stem cells iScience ·Elise Mozin,Emmanuelle Massouridès,Virginie Mournetas,Clémence Lièvre,Audrey Bourdon,Dana L. Jackson,Jonathan S. Packer,Juyoung Seong,Cole Trapnell,Caroline Le Guiner,Oumeya Adjali,Christian Pinset,David L. Mack,Jean‐Baptiste Dupont	2024	1
3	Evaluation of an AAV9-mini-dystrophin gene therapy candidate in a rat model of Duchenne muscular dystrophy Molecular Therapy — Methods & Clinical Development ·Caroline Le Guiner,Xiao Xiao,Thibaut Larcher,Aude Lafoux,Corinne Huchet,Gilles Toumaniantz,Oumeya Adjali,Ignacio Anegón,Séverine Remy,Josh Grieger,Juan Li,Vahid Farrokhi,Hendrik Neubert,Jane Owens,Maritza McIntyre,Philippe Moullier,R. Jude Samulski	2023	12
4	Muscle Pathology in Dystrophic Rats and Zebrafish Is Unresponsive to Taurine Treatment, Compared to the mdx Mouse Model for Duchenne Muscular Dystrophy Metabolites ·Jessica R. Terrill,Corinne Huchet,Caroline Le Guiner,Aude Lafoux,Dorian Caudal,Ankita Tulangekar,Robert J. Bryson‐Richardson,Tamar E. Sztal,Miranda D. Grounds,Peter G. Arthur	2023	2
5	AAV2/9-mediated gene transfer into murine lacrimal gland leads to a long-term targeted tear film modification Molecular Therapy — Methods & Clinical Development ·Benoît Gautier,Léna Meneux,Nadège Feret,Christine Audrain,Laetitia Hudecek,Alison Kuony,Audrey Bourdon,Caroline Le Guiner,Véronique Blouin,Cécile Delettre,Frédéric Michon	2022	4
6	TRPC3, but not TRPC1, as a good therapeutic target for standalone or complementary treatment of DMD Journal of Translational Medicine ·A. Creisméas,Claire Gazaille,Audrey Bourdon,Marc-Antoine Lallemand,Virginie François,Marine Allais,Mireille Ledevin,Thibaut Larcher,Gilles Toumaniantz,Aude Lafoux,Corinne Huchet,Ignacio Anegón,Oumeya Adjali,Caroline Le Guiner,B. Fraysse	2021	11
7	AAV8 locoregional delivery induces long-term expression of an immunogenic transgene in macaques despite persisting local inflammation Molecular Therapy — Methods & Clinical Development ·Gwladys Gernoux,Mickaël Guilbaud,Marie‐Françoise Devaux,Malo Journou,Virginie Pichard,Nicolas Jaulin,Adrien Léger,Johanne Le Duff,Jack‐Yves Deschamps,Caroline Le Guiner,Philippe Moullier,Yan Chérel,Oumeya Adjali	2021	9
8	Dystrophin and mini-dystrophin quantification by mass spectrometry in skeletal muscle for gene therapy development in Duchenne muscular dystrophy Gene Therapy ·Vahid Farrokhi,Jason Walsh,Joe Palandra,Joanne Brodfuehrer,Teresa Caiazzo,Jane Owens,Michael Binks,Srividya Neelakantan,Florence H. Yong,Vivek Dua,Caroline Le Guiner,Hendrik Neubert	2021	17
9	RNA-Seq Analysis of an Antisense Sequence Optimized for Exon Skipping in Duchenne Patients Reveals No Off-Target Effect Molecular Therapy — Nucleic Acids ·Claire Domenger,Marine Allais,Virginie François,Adrien Léger,Émilie Lecomte,Marie Montus,Laurent Servais,Thomas Voit,Philippe Moullier,Yann Audic,Caroline Le Guiner	2017	7
10	Establishment of two quantitative nested qPCR assays targeting the human EPO transgene Gene Therapy ·Elmo W. I. Neuberger,Irene C. Perez,Caroline Le Guiner,Dirk Moser,Tobias Ehlert,M. Allais,Philippe Moullier,Perikles Simon,Richard O. Snyder	2016	29
11	Levels of inflammation and oxidative stress, and a role for taurine in dystropathology of the Golden Retriever Muscular Dystrophy dog model for Duchenne Muscular Dystrophy Redox Biology ·Jessica R. Terrill,Marisa N. Duong,Rufus Turner,Caroline Le Guiner,Amber E. Boyatzis,Anthony J. Kettle,Miranda D. Grounds,Peter G. Arthur	2016	47
12	Serum Profiling Identifies Novel Muscle miRNA and Cardiomyopathy-Related miRNA Biomarkers in Golden Retriever Muscular Dystrophy Dogs and Duchenne Muscular Dystrophy Patients American Journal Of Pathology ·Laurence Jeanson-Leh,Julie Lameth,Soraya Krimi,Julien Buisset,Fatima Amor,Caroline Le Guiner,Inès Barthélémy,Laurent Servais,Stéphane Blot,Thomas Voit,David Israeli	2014	66
13	Characterization of Dystrophin Deficient Rats: A New Model for Duchenne Muscular Dystrophy PLoS ONE ·Thibaut Larcher,Aude Lafoux,Laurent Tesson,Séverine Remy,Virginie Thépenier,Virginie François,Caroline Le Guiner,Hélicia Goubin,Maéva Dutilleul,Lydie Guigand,Gilles Toumaniantz,Anne De Cian,Charlotte Boix,Jean-Baptiste Renaud,Yan Chérel,Carine Giovannangeli,Jean‐Paul Concordet,Ignacio Anegón,Corinne Huchet	2014	135
14	PCR-based detection of gene transfer vectors: application to gene doping surveillance Analytical and Bioanalytical Chemistry ·Irene C. Perez,Caroline Le Guiner,Weiyi Ni,Jennifer K Lyles,Philippe Moullier,Richard O. Snyder	2013	17
15	Development and Utility of an Internal Threshold Control (ITC) Real-Time PCR Assay for Exogenous DNA Detection PLoS ONE ·Weiyi Ni,Caroline Le Guiner,Philippe Moullier,Richard O. Snyder	2012	13
16	Integration Frequency and Intermolecular Recombination of rAAV Vectors in Non-human Primate Skeletal Muscle and Liver Molecular Therapy ·Ali Nowrouzi,Magalie Penaud‐Budloo,Christine Kaeppel,Uwe Appelt,Caroline Le Guiner,Philippe Moullier,Christof von Kalle,Richard O. Snyder,Manfred Schmidt	2012	82
17	In vivo gene regulation using tetracycline-regulatable systems Advanced Drug Delivery Reviews ·Knut Stieger,Brahim Belbellaa,Caroline Le Guiner,Philippe Moullier,Fabienne Rolling	2009	89
18	Lack of Immunotoxicity After Regional Intravenous (RI) Delivery of rAAV to Nonhuman Primate Skeletal Muscle Molecular Therapy ·Alice Toromanoff,Oumeya Adjali,Thibaut Larcher,Marcelo Hill,Lydie Guigand,Pierre Chenuaud,Jack‐Yves Deschamps,Olivier Gauthier,Gilles Blancho,Bernard Vanhove,Fabienne Rolling,Yan Chérel,Philippe Moullier,Ignacio Anegón,Caroline Le Guiner	2009	44
19	Polypyrimidine Tract-binding Protein Represses Splicing of a Fibroblast Growth Factor Receptor-2 Gene Alternative Exon through Exon Sequences Journal of Biological Chemistry ·Caroline Le Guiner,Ariane Plet,Delphine Galiana,Marie-Claude Gesnel,Fabienne Del Gatto–Konczak,Richard Breathnach	2001	25
20	TIA-1 and TIAR Activate Splicing of Alternative Exons with Weak 5′ Splice Sites followed by a U-rich Stretch on Their Own Pre-mRNAs Journal of Biological Chemistry ·Caroline Le Guiner,Fabrice Lejeune,Delphine Galiana,Liliane Kister,Richard Breathnach,James Stévenin,Fabienne Del Gatto–Konczak	2001	117

About Caroline Le Guiner

Caroline Le Guiner is a scholar working on Genetics, Aging and Molecular Biology, having authored 47 papers that have together received 1.6k indexed citations. Recurring topics across this work include Virus-based gene therapy research (25 papers), Muscle Physiology and Disorders (20 papers), RNA Interference and Gene Delivery (13 papers), CRISPR and Genetic Engineering (7 papers), RNA Research and Splicing (6 papers), Tissue Engineering and Regenerative Medicine (4 papers), Cardiomyopathy and Myosin Studies (4 papers) and CAR-T cell therapy research (3 papers). The work is most often cited by research in Genetics (657 citations), Molecular Biology (1.3k citations) and Aging (22 citations). Caroline Le Guiner has collaborated with scholars based in France, United States and United Kingdom. Frequent co-authors include Philippe Moullier, Richard O. Snyder, Fabienne Rolling, Richard Breathnach, Fabienne Del Gatto–Konczak, Yan Chérel, Magalie Penaud‐Budloo, Liliane Kister, Marie-Claude Gesnel and Alice Toromanoff. Their work appears in journals such as Journal of Biological Chemistry, Nature Communications and PLoS ONE.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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