Carl Laxton

2.0k total citations · 1 hit paper
17 papers, 1.6k citations indexed

About

Carl Laxton is a scholar working on Hepatology, Epidemiology and Immunology. According to data from OpenAlex, Carl Laxton has authored 17 papers receiving a total of 1.6k indexed citations (citations by other indexed papers that have themselves been cited), including 10 papers in Hepatology, 9 papers in Epidemiology and 7 papers in Immunology. Recurrent topics in Carl Laxton's work include Hepatitis C virus research (10 papers), Immune Response and Inflammation (5 papers) and Influenza Virus Research Studies (4 papers). Carl Laxton is often cited by papers focused on Hepatitis C virus research (10 papers), Immune Response and Inflammation (5 papers) and Influenza Virus Research Studies (4 papers). Carl Laxton collaborates with scholars based in United Kingdom, United States and Switzerland. Carl Laxton's co-authors include Mathias Müller, James Briscoe, Ian M. Kerr, George R. Stark, T Improta, Christian Schindler, James Darnell, Olli Silvennoinen, Andrew F. Wilks and Andrew Ziemiecki and has published in prestigious journals such as Nature, Nucleic Acids Research and Journal of Biological Chemistry.

In The Last Decade

Carl Laxton

17 papers receiving 1.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The protein tyrosine kinase JAK1 complements defects in interferon-α/β and -γ signal transduction

1993 669 citations Mathias Müller, James Briscoe et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Carl Laxton United Kingdom	11	909	906	498	292	241	17	1.6k
Kathrin Zitzmann Germany	15	855 0.9×	613 0.7×	347 0.7×	518 1.8×	195 0.8×	24	1.6k
Laura Runkel United States	19	776 0.9×	392 0.4×	1.1k 2.2×	668 2.3×	417 1.7×	24	2.2k
Pil Soo Sung South Korea	26	544 0.6×	493 0.5×	434 0.9×	879 3.0×	1.1k 4.6×	149	2.2k
Chun‐Bao Zhou China	15	970 1.1×	476 0.5×	167 0.3×	636 2.2×	474 2.0×	27	1.6k
Boris Blechacz United States	20	285 0.3×	1.3k 1.4×	827 1.7×	423 1.4×	392 1.6×	36	3.2k
Jack T. Lin United States	15	842 0.9×	557 0.6×	348 0.7×	122 0.4×	75 0.3×	22	1.3k
Michael Hahne France	11	1.1k 1.2×	232 0.3×	652 1.3×	260 0.9×	102 0.4×	12	1.7k
Donna Shows United States	11	676 0.7×	329 0.4×	498 1.0×	240 0.8×	44 0.2×	20	1.3k
Matthew Paulson United States	14	273 0.3×	294 0.3×	319 0.6×	399 1.4×	421 1.7×	18	1.0k
Mala Chakraborty United States	21	2.0k 2.1×	2.1k 2.4×	564 1.1×	160 0.5×	119 0.5×	33	3.1k

Countries citing papers authored by Carl Laxton

Since Specialization

Citations

This map shows the geographic impact of Carl Laxton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Carl Laxton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Carl Laxton more than expected).

Fields of papers citing papers by Carl Laxton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Carl Laxton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Carl Laxton. The network helps show where Carl Laxton may publish in the future.

Co-authorship network of co-authors of Carl Laxton

This figure shows the co-authorship network connecting the top 25 collaborators of Carl Laxton. A scholar is included among the top collaborators of Carl Laxton based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Carl Laxton. Carl Laxton is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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17 of 17 papers shown

Laxton, Carl, Andrew Catchpole, E. Donnall Thomas, et al.. (2015). Use of qualitative integrative cycler PCR (qicPCR) to identify optimal therapeutic dosing time-points in a Respiratory Syncytial Virus Human Viral Challenge Model (hVCM). Journal of Virological Methods. 224. 83–90. 6 indexed citations

Colman, Peter, Frances Burden, Carl Laxton, et al.. (2012). Therapy with TLR7 Agonists Induces Lymphopenia: Correlating Pharmacology to Mechanism in a Mouse Model. Journal of Clinical Immunology. 32(5). 1082–1092. 20 indexed citations

Fidock, Mark, Carl Laxton, Peter Colman, et al.. (2011). The Innate Immune Response, Clinical Outcomes, and Ex Vivo HCV Antiviral Efficacy of a TLR7 Agonist (PF-4878691). Clinical Pharmacology & Therapeutics. 89(6). 821–829. 64 indexed citations

Laxton, Carl, Kevin Brady, Sterghios Moschos, et al.. (2011). Selection, Optimization, and Pharmacokinetic Properties of a Novel, Potent Antiviral Locked Nucleic Acid-Based Antisense Oligomer Targeting Hepatitis C Virus Internal Ribosome Entry Site. Antimicrobial Agents and Chemotherapy. 55(7). 3105–3114. 40 indexed citations

Rodrigues, Débora F., et al.. (2010). Use of a highly sensitive strand-specific quantitative PCR to identify abortive replication in the mouse model of respiratory syncytial virus disease. Virology Journal. 7(1). 250–250. 15 indexed citations

Clarke, Sarah L. N., et al.. (2008). Comparison of Rat and Human Responses to Toll-Like Receptor 7 Activation. Journal of Interferon & Cytokine Research. 29(2). 113–126. 3 indexed citations

Laxton, Carl, et al.. (2007). Investigating Toll-Like Receptor Agonists for Potential To Treat Hepatitis C Virus Infection. Antimicrobial Agents and Chemotherapy. 51(8). 2969–2978. 50 indexed citations

Klumpp, Klaus, Vincent Lévêque, Sophie Le Pogam, et al.. (2005). The Novel Nucleoside Analog R1479 (4′-Azidocytidine) Is a Potent Inhibitor of NS5B-dependent RNA Synthesis and Hepatitis C Virus Replication in Cell Culture. Journal of Biological Chemistry. 281(7). 3793–3799. 166 indexed citations

Laxton, Carl, et al.. (2001). Selection of HCV NS5A quasispecies during IFN therapy in patients with chronic HCV.. Digestive Diseases and Sciences. 46(7). 1399–1408. 6 indexed citations

10.

Laxton, Carl, Emma C. Hobbs, Ralf Bartenschlager, et al.. (2001). Characterisation of interferon alfa-2a and pegylated interferon alfa-2A in combination with ribavirin, mycophenolic acid or VX-497 as inhibitors of HCV replicon replication. Journal of Hepatology. 34. 117–118. 3 indexed citations

11.

Laxton, Carl, Emma C. Hobbs, Julian Symons, et al.. (2001). Use of the HCV subgenomic replicon for the selection and characterization of variants with reduced susceptibility to interferon alpha-2A. Journal of Hepatology. 34. 15–15. 2 indexed citations

12.

Laxton, Carl, et al.. (1999). Hepatitis C virus NS5A protein inhibits interferon antiviral activity, but the effects do not correlate with clinical response. Gastroenterology. 117(5). 1187–1197. 66 indexed citations

13.

Laxton, Carl, et al.. (1998). Expression and characterization of the hepatitis G virus helicase. Journal of Viral Hepatitis. 5(1). 21–26. 10 indexed citations

14.

Guille, Matthew, Carl Laxton, Michael Rutherford, Bryan Williams, & Ian M. Kerr. (1994). Functional differences in the promoters of the interferon‐inducible (2′‐5′)A oligoadenylate synthetase and 6–16 genes in interferon‐resistant Daudi cells. European Journal of Biochemistry. 219(1-2). 547–553. 14 indexed citations

15.

Müller, Mathias, James Briscoe, Carl Laxton, et al.. (1993). The protein tyrosine kinase JAK1 complements defects in interferon-α/β and -γ signal transduction. Nature. 366(6451). 129–135. 669 indexed citations breakdown →

16.

Müller, Mathias, Carl Laxton, James Briscoe, et al.. (1993). Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways.. The EMBO Journal. 12(11). 4221–4228. 386 indexed citations

17.

Ackrill, Andrew M., Graham R. Foster, Carl Laxton, et al.. (1991). Inhibition of the cellular response to interferons by products of the adenovirus type 5 E1A oncogene. Nucleic Acids Research. 19(16). 4387–4393. 105 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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