James Briscoe

26.0k total citations · 7 hit papers
169 papers, 18.5k citations indexed

About

James Briscoe is a scholar working on Molecular Biology, Cell Biology and Developmental Neuroscience. According to data from OpenAlex, James Briscoe has authored 169 papers receiving a total of 18.5k indexed citations (citations by other indexed papers that have themselves been cited), including 139 papers in Molecular Biology, 26 papers in Cell Biology and 26 papers in Developmental Neuroscience. Recurrent topics in James Briscoe's work include Developmental Biology and Gene Regulation (86 papers), Hedgehog Signaling Pathway Studies (51 papers) and Pluripotent Stem Cells Research (29 papers). James Briscoe is often cited by papers focused on Developmental Biology and Gene Regulation (86 papers), Hedgehog Signaling Pathway Studies (51 papers) and Pluripotent Stem Cells Research (29 papers). James Briscoe collaborates with scholars based in United Kingdom, United States and Germany. James Briscoe's co-authors include Johan Ericson, Pascal P. Thérond, Thomas M. Jessell, Éric Dessaud, Martin Cheung, Fausto Ulloa, Alessandra Pierani, Andreas Sagner, Hilary L. Ashe and Andrew P. McMahon and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

James Briscoe

162 papers receiving 18.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The mechanisms of Hedgehog signalling and its roles in development and disease

2013 1.4k citations James Briscoe et al. profile →
A Homeodomain Protein Code Specifies Progenitor Cell Identity and Neuronal Fate in the Ventral Neural Tube

2000 900 citations James Briscoe et al. Cell profile →
Pax6 Controls Progenitor Cell Identity and Neuronal Fate in Response to Graded Shh Signaling

1997 835 citations Andreas Schedl, James Briscoe et al. Cell profile →
The protein tyrosine kinase JAK1 complements defects in interferon-α/β and -γ signal transduction

1993 669 citations James Briscoe et al. profile →
Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling

1999 620 citations James Briscoe et al. profile →
Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network

2008 552 citations Éric Dessaud, James Briscoe et al. Development profile →
Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis

2021 169 citations James Briscoe et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
James Briscoe United Kingdom	69	14.8k	3.2k	2.9k	2.4k	2.3k	169	18.5k
Spyros Artavanis‐Tsakonas United States	70	18.1k 1.2×	2.5k 0.8×	1.4k 0.5×	3.2k 1.3×	2.1k 0.9×	121	22.4k
Heiner Westphal United States	73	14.9k 1.0×	5.8k 1.8×	1.8k 0.6×	1.7k 0.7×	1.7k 0.7×	153	22.5k
Shinichi Aizawa Japan	71	13.0k 0.9×	2.6k 0.8×	1.2k 0.4×	3.2k 1.3×	1.9k 0.8×	193	19.5k
Ryoichiro Kageyama Japan	95	20.8k 1.4×	4.0k 1.2×	6.0k 2.1×	2.9k 1.2×	2.1k 0.9×	277	28.3k
Juergen A. Knoblich Austria	74	19.3k 1.3×	2.0k 0.6×	2.8k 1.0×	7.0k 2.9×	3.3k 1.4×	149	27.3k
Michael Wegner Germany	78	12.5k 0.8×	4.5k 1.4×	4.4k 1.5×	1.8k 0.7×	1.2k 0.5×	265	19.9k
Gerry Weinmaster United States	59	10.6k 0.7×	1.7k 0.5×	2.1k 0.7×	1.6k 0.7×	1.0k 0.5×	86	14.4k
Philippe Soriano United States	82	18.1k 1.2×	4.6k 1.4×	1.7k 0.6×	4.5k 1.9×	3.1k 1.4×	150	26.7k
Alexandra L. Joyner United States	87	21.0k 1.4×	6.5k 2.0×	4.1k 1.4×	2.4k 1.0×	1.2k 0.5×	194	27.2k
Marianne Bronner‐Fraser United States	94	22.8k 1.5×	5.8k 1.8×	2.7k 0.9×	4.2k 1.7×	2.3k 1.0×	430	29.5k

Countries citing papers authored by James Briscoe

Since Specialization

Citations

This map shows the geographic impact of James Briscoe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James Briscoe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James Briscoe more than expected).

Fields of papers citing papers by James Briscoe

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James Briscoe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James Briscoe. The network helps show where James Briscoe may publish in the future.

Co-authorship network of co-authors of James Briscoe

This figure shows the co-authorship network connecting the top 25 collaborators of James Briscoe. A scholar is included among the top collaborators of James Briscoe based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James Briscoe. James Briscoe is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Briscoe, James, Craig E. Franklin, Daniel A. Gorelick, E. Elizabeth Patton, & Michael Way. (2025). Science under siege: protecting scientific progress in turbulent times. Biology Open. 14(3).

Briscoe, James, Craig E. Franklin, Daniel A. Gorelick, E. Elizabeth Patton, & Michael Way. (2025). Science under siege: protecting scientific progress in turbulent times. Disease Models & Mechanisms. 18(3). 1 indexed citations

Vigilante, Alessandra, et al.. (2025). Dynamic changes in chromatin accessibility during cell fate specification at the neural plate border. Development. 152(23).

Rito, Tiago, et al.. (2025). An in vivo CRISPR screen in chick embryos reveals a role for MLLT3 in specification of neural cells from the caudal epiblast. Development. 152(3). 1 indexed citations

Rayón, Teresa, Rory J. Maizels, Christopher Barrington, & James Briscoe. (2021). Single-cell transcriptome profiling of the human developing spinal cord reveals a conserved genetic programme with human-specific features. Development. 148(15). 70 indexed citations

Exelby, Katherine, Rubén Perez‐Carrasco, Andreas Sagner, et al.. (2021). Precision of tissue patterning is controlled by dynamical properties of gene regulatory networks. Development. 148(4). 40 indexed citations

Vartanian, Audrey Der, Nabila Elarouci, Frédéric Causeret, et al.. (2020). The PAX-FOXO1s trigger fast trans-differentiation of chick embryonic neural cells into alveolar rhabdomyosarcoma with tissue invasive properties limited by S phase entry inhibition. PLoS Genetics. 16(11). e1009164–e1009164. 11 indexed citations

Rayón, Teresa, Despina Stamataki, Rubén Perez‐Carrasco, et al.. (2020). Species-specific pace of development is associated with differences in protein stability. Science. 369(6510). 151 indexed citations

Comai, Glenda, Markéta Tesařová, Valérie Dupé, et al.. (2020). Local retinoic acid signaling directs emergence of the extraocular muscle functional unit. PLoS Biology. 18(11). e3000902–e3000902. 22 indexed citations

10.

Arber, Silvia & James Briscoe. (2019). Thomas M. Jessell (1951-2019). Development. 146(10). 1 indexed citations

11.

Perez‐Carrasco, Rubén, et al.. (2018). Memory functions reveal structural properties of gene regulatory networks. PLoS Computational Biology. 14(2). e1006003–e1006003. 24 indexed citations

12.

Zagórski, Marcin, Yoji Tabata, Nathalie Brandenberg, et al.. (2017). Decoding of position in the developing neural tube from antiparallel morphogen gradients. Science. 356(6345). 1379–1383. 115 indexed citations

13.

Kutějová, Eva, et al.. (2016). Neural Progenitors Adopt Specific Identities by Directly Repressing All Alternative Progenitor Transcriptional Programs. Developmental Cell. 36(6). 639–653. 62 indexed citations

14.

Jacob, John, Jennifer H. Kong, Steven Moore, et al.. (2013). Retinoid Acid Specifies Neuronal Identity through Graded Expression of Ascl1. Current Biology. 23(5). 412–418. 26 indexed citations

15.

Jacob, John R., Vanessa Ribes, Steven Moore, et al.. (2013). Valproic Acid silencing ofascl1b/ascl1results in the failure of serotonergic differentiation in a zebrafish model of Fetal Valproate Syndrome. Disease Models & Mechanisms. 7(1). 107–17. 31 indexed citations

16.

Matheu, Ander, Manuel Collado, Clare Wise, et al.. (2012). Oncogenicity of the Developmental Transcription Factor Sox9. Cancer Research. 72(5). 1301–1315. 168 indexed citations

17.

Balaskas, Nikolaos, Ana Ribeiro, Jasmina Panovska‐Griffiths, et al.. (2012). Gene Regulatory Logic for Reading the Sonic Hedgehog Signaling Gradient in the Vertebrate Neural Tube. Cell. 148(1-2). 273–284. 328 indexed citations

18.

Briscoe, James, Peter A. Lawrence, & Jean‐Paul Vincent. (2010). Generation and interpretation of morphogen gradients : a subject collection from Cold Spring Harbor perspectives in biology. 6 indexed citations

19.

Zhang, Xiaoyun, Ana Ribeiro, Rong Mo, et al.. (2009). The Kinesin Protein Kif7 Is a Critical Regulator of Gli Transcription Factors in Mammalian Hedgehog Signaling. Science Signaling. 2(76). ra29–ra29. 179 indexed citations

20.

Briscoe, James. (2004). Hedgehog Signaling: Measuring Ligand Concentrations with Receptor Ratios. Current Biology. 14(20). R889–R891. 3 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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