Cahir J. O’Kane

17.5k citations

96 papers · 13.4k indexed · 8 hit papers · h-index 46

Aging top 0.2%
Cellular and Molecular Neuroscience top 0.2%
- Neurobiology and Insect Physiology Research 28
- Genetic Neurodegenerative Diseases 14
- Hereditary Neurological Disorders 12
Cell Biology top 0.1%
- Cellular transport and secretion 17
- Endoplasmic Reticulum Stress and Disease 8
Physiology top 0.2%
Epidemiology top 0.5%
- Autophagy in Disease and Therapy 16
Molecular Biology
- Genomics and Chromatin Dynamics 9
Neurology
- Neurological diseases and metabolism 8

Co-authors: David C. Rubinsztein W J Gehring Brinda Ravikumar Sara Imarisio Zdenek Berger Corinne Vacher Sovan Sarkar Hugo J. Bellen
Cited by: Aging Cellular and Molecular Neuroscience Cell Biology
Partner nations: United Kingdom United States Switzerland

In The Last Decade

Cahir J. O’Kane

95 papers receiving 13.2k citations

Hit Papers

8 papers align trajectories log scale

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2011 Lysosomal positioning coordinates cellular nutrient responses
2010 α-Synuclein impairs macroautophagy: implications for Parkinson’s disease
2008 Novel targets for Huntington's disease in an mTOR-independent autophagy pathway
2005 Rapamycin alleviates toxicity of different aggregate-prone proteins
2004 Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
1995 Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defects
1989 P-element-mediated enhancer detection: a versatile method to study development in Drosophila.
1987 Detection in situ of genomic regulatory elements in Drosophila.

Peers

Countries citing papers authored by Cahir J. O’Kane

Since Specialization

Citations

This map shows the geographic impact of Cahir J. O’Kane's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Cahir J. O’Kane with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Cahir J. O’Kane more than expected).

Fields of papers citing papers by Cahir J. O’Kane

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Cahir J. O’Kane. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Cahir J. O’Kane. The network helps show where Cahir J. O’Kane may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Cahir J. O’Kane, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Cahir J. O’Kane Line = papers co-authored together Cahir J. O’Kane links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Drosophila SPG12 ortholog, reticulon-like 1, governs presynaptic ER organization and Ca2+ dynamics Juan José Pérez-Moreno,Rebecca C. Smith,Megan Oliva,Filomena Gallo,Shainy Ojha,Karin H. Müller,Cahir J. O’Kane	2023	4
2	Endoplasmic Reticulum Lumenal Indicators in Drosophila Reveal Effects of HSP-Related Mutations on Endoplasmic Reticulum Calcium Dynamics Megan Oliva,Juan José Pérez-Moreno,Jillian O’Shaughnessy,Trevor J. Wardill,Cahir J. O’Kane	2020	12
3	Active zone scaffolds differentially accumulate Unc13 isoforms to tune Ca2+ channel–vesicle coupling Mathias A. Böhme,Christina Beis,Suneel Reddy‐Alla,Eric Reynolds,Malou M Mampell,Andreas T. Grasskamp,Janine Lützkendorf,Dominique Dufour Bergeron,J.H. Driller,Husam Babikir,Fabian Göttfert,Iain M. Robinson,Cahir J. O’Kane,Stefan W. Hell,M.C. Wahl,Ulrich Stelzl,Bernhard Loll,Alexander M. Walter,Stephan J. Sigrist	2016	140
4	Drosophila Vps35 function is necessary for normal endocytic trafficking and actin cytoskeleton organisation Viktor I. Korolchuk,Martin M. Schütz,Carolina Gómez‐Llorente,João Rocha,Nico Lansu,Stéphanie Collins,Yogesh P. Wairkar,Iain M. Robinson,Cahir J. O’Kane	2007	75
5	Eps15 and Dap160 control synaptic vesicle membrane retrieval and synapse development Tong‐Wey Koh,Viktor I. Korolchuk,Yogesh P. Wairkar,Wei Jiao,Emma Evergren,Hongling Pan,Yi Zhou,Koen J. T. Venken,Oleg Shupliakov,Iain M. Robinson,Cahir J. O’Kane,Hugo J. Bellen	2007	103
6	A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin Sovan Sarkar,Gauri Krishna,Sara Imarisio,Shinji Saiki,Cahir J. O’Kane,David C. Rubinsztein	2007	290
7	Stereotypic and random patterns of connectivity in the larval mushroom body calyx of Drosophila Liria M. Masuda-Nakagawa,Nobuaki Tanaka,Cahir J. O’Kane	2005	66
8	Dynein mutations impair autophagic clearance of aggregate-prone proteins Brinda Ravikumar,Abraham Acevedo‐Arozena,Sara Imarisio,Zdenek Berger,Corinne Vacher,Cahir J. O’Kane,Steve D. M. Brown,David C. Rubinsztein	2005	366
9	Dyneins, Autophagy, Aggregation and Neurodegeneration David C. Rubinsztein,Brinda Ravikumar,Abraham Acevedo‐Arozena,Sara Imarisio,Cahir J. O’Kane,Steve D. M. Brown	2005	40
10	Shaw potassium channel genes inDrosophila James J. L. Hodge,James C. Choi,Cahir J. O’Kane,Leslie C. Griffith	2005	38
11	Comparative evolutionary analysis of VPS33 homologues: genetic and functional insights Paul Gissen,Colin A. Johnson,Dean Gentle,Laurence D. Hurst,Aidan J. Doherty,Cahir J. O’Kane,Déirdre Kelly,Eamonn R. Maher	2005	45
12	Lithium rescues toxicity of aggregate-prone proteins in Drosophila by perturbing Wnt pathway Zdenek Berger,Evangelia K. Ttofi,Claire H. Michel,Matthieu Y. Pasco,Sean Tenant,David C. Rubinsztein,Cahir J. O’Kane	2005	59
13	Members of the synaptobrevin/vesicle-associated membrane protein (VAMP) family in Drosophila are functionally interchangeable in vivo for neurotransmitter release and cell viability Sharmila Bhattacharya,Bryan A. Stewart,Barbara A. Niemeyer,Robert W. Burgess,Brian D. McCabe,Peter H. Lin,Gabrielle L. Boulianne,Cahir J. O’Kane,Thomas L. Schwarz	2002	69
14	Targeted expression of tetanus neurotoxin interferes with behavioral responses to sensory input in Drosophila Andreas Keller,Sean T. Sweeney,Troy Zars,Cahir J. O’Kane,Martin Heisenberg	2002	41
15	Dribble, theDrosophilaKRR1p Homologue, Is Involved in rRNA Processing Ho Yin Edwin Chan,Saverio Brogna,Cahir J. O’Kane	2001	18
16	The Partner of Inscuteable/Discs-Large Complex Is Required to Establish Planar Polarity during Asymmetric Cell Division in Drosophila Yohanns Bellaı̈che,Anna Radovic,Daniel F. Woods,Colleen D. Hough,Marie‐Laure Parmentier,Cahir J. O’Kane,Peter J. Bryant,François Schweisguth	2001	190
17	Sexual behaviour: Courting dissatisfaction Cahir J. O’Kane,Zoltén Asztalos	1999	6
18	Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defectsbreakdown → Sean T. Sweeney,Kendal Broadie,John Keane,Heiner Niemann,Cahir J. O’Kane	1995	704
19	Syntaxin and synaptobrevin function downstream of vesicle docking in drosophila Kendal Broadie,Andreas Prokop,Hugo J. Bellen,Cahir J. O’Kane,Karen L. Schulze,Sean T. Sweeney	1995	306
20	Research letterMapping of the gene for endo-β-1,3-1,4-glucanase of Bacillus subtilis Cahir J. O’Kane,B. A. Cantwell,David J. McConnell	1985	1

About Cahir J. O’Kane

Cahir J. O’Kane is a scholar working on Cellular and Molecular Neuroscience, Aging and Cell Biology, having authored 96 papers that have together received 13.4k indexed citations. Recurring topics across this work include Neurobiology and Insect Physiology Research (28 papers), Cellular transport and secretion (17 papers), Autophagy in Disease and Therapy (16 papers), Genetic Neurodegenerative Diseases (14 papers), Hereditary Neurological Disorders (12 papers), Genomics and Chromatin Dynamics (9 papers), Neurological diseases and metabolism (8 papers) and Endoplasmic Reticulum Stress and Disease (8 papers). The work is most often cited by research in Aging (550 citations), Cellular and Molecular Neuroscience (4.8k citations) and Cell Biology (3.7k citations). Cahir J. O’Kane has collaborated with scholars based in United Kingdom, United States and Switzerland. Frequent co-authors include David C. Rubinsztein, W J Gehring, Brinda Ravikumar, Sara Imarisio, Zdenek Berger, Corinne Vacher, Sovan Sarkar, Hugo J. Bellen, Sean T. Sweeney and Shouqing Luo.

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