Cahir J. O’Kane

17.5k citations

96 papers · 13.4k indexed · 8 hit papers · h-index 46

Molecular Biology top 0.5%
Cellular and Molecular Neuroscience top 0.2%
Epidemiology top 0.5%
Cell Biology top 0.1%
Physiology top 1%

Co-authors: David C. Rubinsztein W J Gehring Brinda Ravikumar Sara Imarisio Zdenek Berger Corinne Vacher Sovan Sarkar Hugo J. Bellen
Topics: Neurobiology and Insect Physiology Research (28 papers)Cellular transport and secretion (17 papers)Autophagy in Disease and Therapy (16 papers)
Cited by: Aging Cellular and Molecular Neuroscience Cell Biology
Journals: Science Cell Proceedings of the National Academy of Sciences
Partner nations: United Kingdom United States Switzerland

In The Last Decade

Cahir J. O’Kane

95 papers receiving 13.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

2004 1.9k citations Brinda Ravikumar, Corinne Vacher et al. Nature Genetics profile →
Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defects

1995 704 citations Sean T. Sweeney, Kendal Broadie et al. Neuron profile →
Lysosomal positioning coordinates cellular nutrient responses

2011 671 citations Viktor I. Korolchuk, Shinji Saiki et al. profile →
α-Synuclein impairs macroautophagy: implications for Parkinson’s disease

2010 651 citations Abraham Acevedo‐Arozena, Brinda Ravikumar et al. The Journal of Cell Biology profile →
Detection in situ of genomic regulatory elements in Drosophila.

1987 639 citations Cahir J. O’Kane et al. Proceedings of the National Academy of Sciences profile →
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

2008 638 citations Sovan Sarkar, Shinji Saiki et al. profile →
P-element-mediated enhancer detection: a versatile method to study development in Drosophila.

1989 583 citations Hugo J. Bellen, Cahir J. O’Kane et al. profile →
Rapamycin alleviates toxicity of different aggregate-prone proteins

2005 532 citations Zdenek Berger, Brinda Ravikumar et al. Human Molecular Genetics profile →

Peers

Countries citing papers authored by Cahir J. O’Kane

Since Specialization

Citations

This map shows the geographic impact of Cahir J. O’Kane's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Cahir J. O’Kane with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Cahir J. O’Kane more than expected).

Fields of papers citing papers by Cahir J. O’Kane

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Cahir J. O’Kane. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Cahir J. O’Kane. The network helps show where Cahir J. O’Kane may publish in the future.

Co-authorship network of co-authors of Cahir J. O’Kane

This figure shows the co-authorship network connecting the top 25 collaborators of Cahir J. O’Kane. A scholar is included among the top collaborators of Cahir J. O’Kane based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Cahir J. O’Kane. Cahir J. O’Kane is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Drosophila SPG12 ortholog, reticulon-like 1, governs presynaptic ER organization and Ca2+ dynamics 2023 ·The Journal of Cell Biology ·(unknown),Rebecca C. Smith,(unknown),(unknown),(unknown),Karin H. Müller,Cahir J. O’Kane	4
2	Endoplasmic Reticulum Lumenal Indicators in Drosophila Reveal Effects of HSP-Related Mutations on Endoplasmic Reticulum Calcium Dynamics 2020 ·Frontiers in Neuroscience ·(unknown),(unknown),(unknown),Trevor J. Wardill,Cahir J. O’Kane	12
3	Active zone scaffolds differentially accumulate Unc13 isoforms to tune Ca2+ channel–vesicle coupling 2016 ·Nature Neuroscience ·Mathias A. Böhme,(unknown),Suneel Reddy‐Alla,Eric Reynolds,(unknown),Andreas T. Grasskamp,Janine Lützkendorf,(unknown),J.H. Driller,Husam Babikir,Fabian Göttfert,Iain M. Robinson,Cahir J. O’Kane,Stefan W. Hell,M.C. Wahl,Ulrich Stelzl,Bernhard Loll,Alexander M. Walter,Stephan J. Sigrist	140
4	Drosophila Vps35 function is necessary for normal endocytic trafficking and actin cytoskeleton organisation 2007 ·Journal of Cell Science ·Viktor I. Korolchuk,(unknown),Carolina Gómez‐Llorente,João Rocha,Nico Lansu,Stéphanie Collins,Yogesh P. Wairkar,Iain M. Robinson,Cahir J. O’Kane	75
5	Eps15 and Dap160 control synaptic vesicle membrane retrieval and synapse development 2007 ·The Journal of Cell Biology ·Tong‐Wey Koh,Viktor I. Korolchuk,Yogesh P. Wairkar,Wei Jiao,Emma Evergren,Hongling Pan,Yi Zhou,Koen J. T. Venken,Oleg Shupliakov,Iain M. Robinson,Cahir J. O’Kane,Hugo J. Bellen	103
6	A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin 2007 ·Human Molecular Genetics ·Sovan Sarkar,(unknown),Sara Imarisio,Shinji Saiki,Cahir J. O’Kane,David C. Rubinsztein	290
7	Stereotypic and random patterns of connectivity in the larval mushroom body calyx of Drosophila 2005 ·Proceedings of the National Academy of Sciences ·Liria M. Masuda-Nakagawa,Nobuaki Tanaka,Cahir J. O’Kane	66
8	Dynein mutations impair autophagic clearance of aggregate-prone proteins 2005 ·Nature Genetics ·Brinda Ravikumar,Abraham Acevedo‐Arozena,Sara Imarisio,Zdenek Berger,Corinne Vacher,Cahir J. O’Kane,Steve D. M. Brown,David C. Rubinsztein	366
9	Dyneins, Autophagy, Aggregation and Neurodegeneration 2005 ·Autophagy ·David C. Rubinsztein,Brinda Ravikumar,Abraham Acevedo‐Arozena,Sara Imarisio,Cahir J. O’Kane,Steve D. M. Brown	40
10	Shaw potassium channel genes inDrosophila 2005 ·Journal of Neurobiology ·James J. L. Hodge,(unknown),Cahir J. O’Kane,Leslie C. Griffith	38
11	Comparative evolutionary analysis of VPS33 homologues: genetic and functional insights 2005 ·Human Molecular Genetics ·Paul Gissen,Colin A. Johnson,Dean Gentle,Laurence D. Hurst,Aidan J. Doherty,Cahir J. O’Kane,Déirdre Kelly,Eamonn R. Maher	45
12	Lithium rescues toxicity of aggregate-prone proteins in Drosophila by perturbing Wnt pathway 2005 ·Human Molecular Genetics ·Zdenek Berger,(unknown),Claire H. Michel,Matthieu Y. Pasco,(unknown),David C. Rubinsztein,Cahir J. O’Kane	59
13	Members of the synaptobrevin/vesicle-associated membrane protein (VAMP) family in Drosophila are functionally interchangeable in vivo for neurotransmitter release and cell viability 2002 ·Proceedings of the National Academy of Sciences ·Sharmila Bhattacharya,Bryan A. Stewart,Barbara A. Niemeyer,Robert W. Burgess,Brian D. McCabe,Peter H. Lin,Gabrielle L. Boulianne,Cahir J. O’Kane,Thomas L. Schwarz	69
14	Targeted expression of tetanus neurotoxin interferes with behavioral responses to sensory input in Drosophila 2002 ·Journal of Neurobiology ·Andreas Keller,Sean T. Sweeney,Troy Zars,Cahir J. O’Kane,Martin Heisenberg	41
15	Dribble, theDrosophilaKRR1p Homologue, Is Involved in rRNA Processing 2001 ·Molecular Biology of the Cell ·Ho Yin Edwin Chan,Saverio Brogna,Cahir J. O’Kane	18
16	The Partner of Inscuteable/Discs-Large Complex Is Required to Establish Planar Polarity during Asymmetric Cell Division in Drosophila 2001 ·Cell ·Yohanns Bellaı̈che,(unknown),Daniel F. Woods,Colleen D. Hough,Marie‐Laure Parmentier,Cahir J. O’Kane,Peter J. Bryant,François Schweisguth	190
17	Sexual behaviour: Courting dissatisfaction 1999 ·Current Biology ·Cahir J. O’Kane,(unknown)	6
18	Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defectsbreakdown → 1995 ·Neuron ·Sean T. Sweeney,Kendal Broadie,John Keane,Heiner Niemann,Cahir J. O’Kane	704
19	Syntaxin and synaptobrevin function downstream of vesicle docking in drosophila 1995 ·Neuron ·Kendal Broadie,Andreas Prokop,Hugo J. Bellen,Cahir J. O’Kane,Karen L. Schulze,Sean T. Sweeney	306
20	Research letterMapping of the gene for endo-β-1,3-1,4-glucanase of Bacillus subtilis 1985 ·FEMS Microbiology Letters ·Cahir J. O’Kane,(unknown),David J. McConnell	1

About Cahir J. O’Kane

Cahir J. O’Kane is a scholar working on Cellular and Molecular Neuroscience, Aging and Cell Biology, having authored 96 papers that have together received 13.4k indexed citations. Recurring topics across this work include Neurobiology and Insect Physiology Research (28 papers), Cellular transport and secretion (17 papers) and Autophagy in Disease and Therapy (16 papers). The work is most often cited by research in Aging (550 citations), Cellular and Molecular Neuroscience (4.8k citations) and Cell Biology (3.7k citations). Cahir J. O’Kane has collaborated with scholars based in United Kingdom, United States and Switzerland. Frequent co-authors include David C. Rubinsztein, W J Gehring, Brinda Ravikumar, Sara Imarisio, Zdenek Berger, Corinne Vacher, Sovan Sarkar, Hugo J. Bellen, Sean T. Sweeney and Shouqing Luo. Their work appears in journals such as Science, Cell and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact