Brian L. Hanzelka

3.3k citations

23 papers · 2.5k indexed · 1 hit paper · h-index 18

Co-authors: E. Peter Greenberg Dale L. Val John E. Cronan Amy L. Schaefer Matthew R. Parsek Ute Müh Anatol Eberhard Doug J. Bartels
Topics: Bacterial biofilms and quorum sensing (7 papers)Hepatitis C virus research (6 papers)bioluminescence and chemiluminescence research (5 papers)
Cited by: Hepatology Endocrinology Molecular Medicine
Journals: Proceedings of the National Academy of Sciences Journal of Biological Chemistry Gastroenterology
Partner nations: United States Italy Sweden

In The Last Decade

Brian L. Hanzelka

23 papers receiving 2.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Dynamic Hepatitis C Virus Genotypic and Phenotypic Changes in Patients Treated With the Protease Inhibitor Telaprevir

2007 476 citations Christoph Sarrazin, Tara L. Kieffer et al. Gastroenterology profile →

Peers

Countries citing papers authored by Brian L. Hanzelka

Since Specialization

Citations

This map shows the geographic impact of Brian L. Hanzelka's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brian L. Hanzelka with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brian L. Hanzelka more than expected).

Fields of papers citing papers by Brian L. Hanzelka

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brian L. Hanzelka. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brian L. Hanzelka. The network helps show where Brian L. Hanzelka may publish in the future.

Co-authorship network of co-authors of Brian L. Hanzelka

This figure shows the co-authorship network connecting the top 25 collaborators of Brian L. Hanzelka. A scholar is included among the top collaborators of Brian L. Hanzelka based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Brian L. Hanzelka. Brian L. Hanzelka is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions 2017 ·ACS Medicinal Chemistry Letters ·Tiansheng Wang,Guy W. Bemis,Brian L. Hanzelka,Harmon Zuccola,(unknown),Cameron Stuver Moody,Jeremy Green,Christopher P. Locher,Aixiang Liu,Hongwu Gao,Yuzhou Xu,Shaohui Wang,Jie Wang,Youssef L. Bennani,John A. Thomson,Ute Müh	40
2	Discovery and Characterization of a Water-Soluble Prodrug of a Dual Inhibitor of Bacterial DNA Gyrase and Topoisomerase IV 2015 ·ACS Medicinal Chemistry Letters ·Hardwin O’Dowd,Dean Shannon,(unknown),Vaishali Dixit,(unknown),(unknown),Steven M. Jones,(unknown),David P. Nicolau,Pamela R. Tessier,Jared L. Crandon,Bin Song,Dainius Macikenas,Brian L. Hanzelka,Arnaud LeTiran,Youssef L. Bennani,Paul S. Charifson,Anne‐Laure Grillot	19
3	High in vitro activity of a novel dual bacterial topoisomerase inhibitor of the ATPase activities of GyrB and ParE (VT12-008911) against Neisseria gonorrhoeae isolates with various high-level antimicrobial resistance and multidrug resistance 2014 ·Journal of Antimicrobial Chemotherapy ·Samo Jeverica,Daniel Golparian,Brian L. Hanzelka,(unknown),(unknown),Magnus Unemo	13
4	A Novel Inhibitor of Gyrase B Is a Potent Drug Candidate for Treatment of Tuberculosis and Nontuberculosis Mycobacterial Infections 2014 ·Antimicrobial Agents and Chemotherapy ·Christopher P. Locher,Steven M. Jones,Brian L. Hanzelka,Emanuele Perola,Carolyn Shoen,Michael H. Cynamon,(unknown),Ian Wiid,Paul D. van Helden,Fabrice Betoudji,Eric L. Nuermberger,John A. Thomson	69
5	In Vitro Phenotypic Characterization of Hepatitis C Virus NS3 Protease Variants Observed in Clinical Studies of Telaprevir 2013 ·Antimicrobial Agents and Chemotherapy ·Min Jiang,Nagraj Mani,Chao Lin,(unknown),Michelle Nelson,(unknown),Doug J. Bartels,Yi Zhou,Olivier Nicolas,B. Govinda Rao,Ute Müh,Brian L. Hanzelka,Ann M. Tigges,René Rijnbrand,Tara L. Kieffer	25
6	Phenotypic and Structural Analyses of Hepatitis C Virus NS3 Protease Arg155 Variants 2007 ·Journal of Biological Chemistry ·Yi Zhou,(unknown),Brian L. Hanzelka,Doug J. Bartels,Yunyi Wei,B. Govinda Rao,Debra Brennan,Ann M. Tigges,Lora Swenson,Ann D. Kwong,Chao Lin	71
7	Dynamic Hepatitis C Virus Genotypic and Phenotypic Changes in Patients Treated With the Protease Inhibitor Telaprevirbreakdown → 2007 ·Gastroenterology ·Christoph Sarrazin,Tara L. Kieffer,Doug J. Bartels,Brian L. Hanzelka,Ute Müh,Martin Welker,Dennis Wincheringer,Yi Zhou,Hui‐May Chu,Chao Lin,Christine J. Weegink,H. W. Reesink,Stefan Zeuzem,Ann D. Kwong	476
8	[12] TELAPREVIR (VX-950) IS A POTENT INHIBITOR OF HCV NS3 PROTEASES DERIVED FROM GENOTYPE NON-1 HCV-INFECTED PATIENTS 2007 ·Journal of Hepatology ·(unknown),Brian L. Hanzelka,Ute Müh,Ladislau C. Kovari,Doug J. Bartels,Ann M. Tigges,Jeffrey D. Miller,B. Govinda Rao,Ann D. Kwong	7
9	Phenotypic Characterization of Resistant Val³⁶Variants of Hepatitis C Virus NS3-4A Serine Protease 2007 ·Antimicrobial Agents and Chemotherapy ·Yi Zhou,Doug J. Bartels,Brian L. Hanzelka,Ute Müh,Yunyi Wei,Hui‐May Chu,Ann M. Tigges,Debra Brennan,B. Govinda Rao,Lora Swenson,Ann D. Kwong,Chao Lin	79
10	A structurally unrelated mimic of a Pseudomonas aeruginosa acyl-homoserine lactone quorum-sensing signal 2006 ·Proceedings of the National Academy of Sciences ·Ute Müh,Brian Hare,Breck A. Duerkop,Martín Schuster,Brian L. Hanzelka,Roger Heim,Eric R. Olson,E. Peter Greenberg	111
11	In Vitro Characterization of the Antibacterial Spectrum of Novel Bacterial Type II Topoisomerase Inhibitors of the Aminobenzimidazole Class 2006 ·Antimicrobial Agents and Chemotherapy ·Nagraj Mani,Christian H. Gross,Jonathan D. Parsons,Brian L. Hanzelka,Ute Müh,Steve Mullin,Yusheng Liao,Anne‐Laure Grillot,Dean Stamos,Paul S. Charifson,Trudy H. Grossman	64
12	TFE, an Archaeal Transcription Factor in Methanobacterium thermoautotrophicum Related to Eucaryal Transcription Factor TFIIEα 2001 ·Journal of Bacteriology ·Brian L. Hanzelka,(unknown),John N. Reeve	65
13	Detection, purification, and structural elucidation of the acylhomoserine lactone inducer of Vibrio fischeri luminescence and other related molecules 2000 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Amy L. Schaefer,Brian L. Hanzelka,Matthew R. Parsek,E. Peter Greenberg	93
14	Acylhomoserine Lactone Synthase Activity of the Vibrio fischeri AinS Protein 1999 ·Journal of Bacteriology ·Brian L. Hanzelka,Matthew R. Parsek,Dale L. Val,Paul V. Dunlap,John E. Cronan,E. Peter Greenberg	87
15	Acyl homoserine-lactone quorum-sensing signal generation 1999 ·Proceedings of the National Academy of Sciences ·Matthew R. Parsek,Dale L. Val,Brian L. Hanzelka,John E. Cronan,E. Peter Greenberg	408
16	Quorum sensing in Vibrio fischeri: probing autoinducer-LuxR interactions with autoinducer analogs 1996 ·Journal of Bacteriology ·Amy L. Schaefer,Brian L. Hanzelka,Anatol Eberhard,E. Peter Greenberg	220
17	Quorum sensing in Vibrio fischeri: evidence that S-adenosylmethionine is the amino acid substrate for autoinducer synthesis 1996 ·Journal of Bacteriology ·Brian L. Hanzelka,E. Peter Greenberg	107
18	Survey of Intestinal Spirochaetes for NADH Oxidase by Gene Probe and by Enzyme Assay 1995 ·Microbial Ecology in Health and Disease ·Thad B. Stanton,Brian L. Hanzelka,Neil S. Jensen	10
19	Evidence that the N-terminal region of the Vibrio fischeri LuxR protein constitutes an autoinducer-binding domain 1995 ·Journal of Bacteriology ·Brian L. Hanzelka,E. Peter Greenberg	162
20	Survey of Intestinal Spirochaetes for NADH Oxidase by Gene Probe and by Enzyme Assay 1994 ·Microbial Ecology in Health and Disease ·Thad B. Stanton,Brian L. Hanzelka,Neil S. Jensen	11

About Brian L. Hanzelka

Brian L. Hanzelka is a scholar working on Molecular Medicine, Hepatology and Infectious Diseases, having authored 23 papers that have together received 2.5k indexed citations. Recurring topics across this work include Bacterial biofilms and quorum sensing (7 papers), Hepatitis C virus research (6 papers) and bioluminescence and chemiluminescence research (5 papers). The work is most often cited by research in Hepatology (644 citations), Endocrinology (317 citations) and Molecular Medicine (291 citations). Brian L. Hanzelka has collaborated with scholars based in United States, Italy and Sweden. Frequent co-authors include E. Peter Greenberg, Dale L. Val, John E. Cronan, Amy L. Schaefer, Matthew R. Parsek, Ute Müh, Anatol Eberhard, Doug J. Bartels, Chao Lin and Yi Zhou. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Gastroenterology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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