Brent J. Ryan

3.4k total citations · 2 hit papers
35 papers, 2.4k citations indexed

About

Brent J. Ryan is a scholar working on Neurology, Cellular and Molecular Neuroscience and Molecular Biology. According to data from OpenAlex, Brent J. Ryan has authored 35 papers receiving a total of 2.4k indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Neurology, 12 papers in Cellular and Molecular Neuroscience and 11 papers in Molecular Biology. Recurrent topics in Brent J. Ryan's work include Parkinson's Disease Mechanisms and Treatments (17 papers), Autophagy in Disease and Therapy (8 papers) and Alzheimer's disease research and treatments (6 papers). Brent J. Ryan is often cited by papers focused on Parkinson's Disease Mechanisms and Treatments (17 papers), Autophagy in Disease and Therapy (8 papers) and Alzheimer's disease research and treatments (6 papers). Brent J. Ryan collaborates with scholars based in United Kingdom, United States and Denmark. Brent J. Ryan's co-authors include Richard Wade‐Martins, Edward A. Fon, Ana Belén Malpartida, Derek P. Narendra, Paul G. Winyard, Ahuva Nissim, Sally A. Cowley, Jane Vowles, Charmaine Lang and Helle Bogetofte and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Neuroscience and Scientific Reports.

In The Last Decade

Brent J. Ryan

35 papers receiving 2.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease

2015 417 citations Brent J. Ryan, Edward A. Fon et al. Trends in Biochemical Sciences profile →
Mitochondrial Dysfunction and Mitophagy in Parkinson’s Disease: From Mechanism to Therapy

2020 344 citations Ana Belén Malpartida, Derek P. Narendra et al. Trends in Biochemical Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Brent J. Ryan United Kingdom	24	1.1k	1.0k	660	601	418	35	2.4k
Mariana Pehar United States	33	1.5k 1.4×	1.1k 1.1×	569 0.9×	822 1.4×	257 0.6×	50	3.4k
Shigeki Arawaka Japan	31	890 0.8×	1.1k 1.0×	744 1.1×	1.0k 1.7×	251 0.6×	81	2.7k
Vanessa A. Morais Portugal	27	1.7k 1.6×	762 0.7×	441 0.7×	653 1.1×	612 1.5×	56	2.8k
Marie‐Paule Muriel France	22	1.2k 1.1×	841 0.8×	1.1k 1.6×	322 0.5×	187 0.4×	30	2.5k
Davide Chiasserini Italy	31	1.0k 1.0×	1.6k 1.5×	474 0.7×	1.4k 2.4×	236 0.6×	83	3.5k
Makiko Nagai Japan	27	1.2k 1.1×	2.1k 2.0×	803 1.2×	521 0.9×	290 0.7×	61	3.4k
С. Н. Иллариошкин Russia	25	1.1k 1.1×	816 0.8×	859 1.3×	445 0.7×	132 0.3×	308	2.3k
Alicia M. Pickrell United States	18	1.8k 1.7×	855 0.8×	515 0.8×	591 1.0×	1.1k 2.7×	35	2.9k
Joakim Bergström Sweden	24	947 0.9×	1.1k 1.1×	610 0.9×	839 1.4×	137 0.3×	51	2.4k
Hélène Plun‐Favreau United Kingdom	29	2.0k 2.0×	1.6k 1.6×	814 1.2×	798 1.3×	1.1k 2.7×	44	3.9k

Countries citing papers authored by Brent J. Ryan

Since Specialization

Citations

This map shows the geographic impact of Brent J. Ryan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Brent J. Ryan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Brent J. Ryan more than expected).

Fields of papers citing papers by Brent J. Ryan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Brent J. Ryan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Brent J. Ryan. The network helps show where Brent J. Ryan may publish in the future.

Co-authorship network of co-authors of Brent J. Ryan

This figure shows the co-authorship network connecting the top 25 collaborators of Brent J. Ryan. A scholar is included among the top collaborators of Brent J. Ryan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Brent J. Ryan. Brent J. Ryan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Mikulski, Paweł, et al.. (2025). Heritable maintenance of chromatin modifications confers transcriptional memory of interferon-γ signaling. Nature Structural & Molecular Biology. 32(7). 1255–1267. 2 indexed citations

Mock, Elliot D., Kaitlyn M. L. Cramb, Ana Belén Malpartida, et al.. (2023). Mitochondrial dysfunction and mitophagy defects in LRRK2-R1441C Parkinson’s disease models. Human Molecular Genetics. 32(18). 2808–2821. 27 indexed citations

Fernandopulle, Michael S., Ashley M. Frankenfield, Haorong Li, et al.. (2023). Multi-modal proteomic characterization of lysosomal function and proteostasis in progranulin-deficient neurons. Molecular Neurodegeneration. 18(1). 87–87. 9 indexed citations

Threlfell, Sarah, Brent J. Ryan, Natalie Connor‐Robson, et al.. (2021). Striatal Dopamine Transporter Function Is Facilitated by Converging Biology of α-Synuclein and Cholesterol. Frontiers in Cellular Neuroscience. 15. 658244–658244. 22 indexed citations

Okarmus, Justyna, Jesper F. Havelund, Matias Ryding, et al.. (2021). Identification of bioactive metabolites in human iPSC-derived dopaminergic neurons with PARK2 mutation: Altered mitochondrial and energy metabolism. Stem Cell Reports. 16(6). 1510–1526. 29 indexed citations

Ryan, Brent J., Nora Bengoa‐Vergniory, Rosalind F. Roberts, et al.. (2021). REST Protects Dopaminergic Neurons from Mitochondrial and α-Synuclein Oligomer Pathology in an Alpha Synuclein Overexpressing BAC-Transgenic Mouse Model. Journal of Neuroscience. 41(16). 3731–3746. 21 indexed citations

Malpartida, Ana Belén, et al.. (2020). Mitochondrial Dysfunction and Mitophagy in Parkinson’s Disease: From Mechanism to Therapy. Trends in Biochemical Sciences. 46(4). 329–343. 344 indexed citations breakdown →

Bogetofte, Helle, Pia Jensen, Matias Ryding, et al.. (2019). PARK2 Mutation Causes Metabolic Disturbances and Impaired Survival of Human iPSC-Derived Neurons. Frontiers in Cellular Neuroscience. 13. 297–297. 46 indexed citations

Finelli, Mattéa J., Teresa Páramo, Elisabete Pires, et al.. (2018). Oxidation Resistance 1 Modulates Glycolytic Pathways in the Cerebellum via an Interaction with Glucose-6-Phosphate Isomerase. Molecular Neurobiology. 56(3). 1558–1577. 14 indexed citations

10.

Lang, Charmaine, Kieran R. Campbell, Brent J. Ryan, et al.. (2018). Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes. Cell stem cell. 24(1). 93–106.e6. 106 indexed citations

11.

Bailey, Jade, Andrew Shaw, Román Fischer, et al.. (2017). A novel role for endothelial tetrahydrobiopterin in mitochondrial redox balance. Free Radical Biology and Medicine. 104. 214–225. 46 indexed citations

12.

Lai, Mang Ching, Franziska Denk, Emma Collins, et al.. (2017). Haplotype-specific MAPT exon 3 expression regulated by common intronic polymorphisms associated with Parkinsonian disorders. Molecular Neurodegeneration. 12(1). 79–79. 9 indexed citations

13.

Buttgereit, Jens, Julia Shanks, Dan Li, et al.. (2016). C-type natriuretic peptide and natriuretic peptide receptor B signalling inhibits cardiac sympathetic neurotransmission and autonomic function. Cardiovascular Research. 112(3). 637–644. 31 indexed citations

14.

Szabó-Taylor, Katalin, Brent J. Ryan, Xabier Osteikoetxea, et al.. (2015). Oxidative and other posttranslational modifications in extracellular vesicle biology. Seminars in Cell and Developmental Biology. 40. 8–16. 43 indexed citations

15.

Ryan, Brent J., et al.. (2015). Protein-protein interaction networks identify targets which rescue the MPP+ cellular model of Parkinson’s disease. Scientific Reports. 5(1). 17004–17004. 26 indexed citations

16.

Ryan, Brent J., et al.. (2015). Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease. Trends in Biochemical Sciences. 40(4). 200–210. 417 indexed citations breakdown →

17.

Ryan, Brent J. & Paul Eggleton. (2014). Detection and Characterization of Autoantibodies Against Modified Self-Proteins in SLE Sera After Exposure to Reactive Oxygen and Nitrogen Species. Methods in molecular biology. 1134. 163–171. 5 indexed citations

18.

Douglas, Gillian, Ashley Hale, Mark J. Crabtree, et al.. (2014). A requirement for Gch1 and tetrahydrobiopterin in embryonic development. Developmental Biology. 399(1). 129–138. 31 indexed citations

19.

Eggleton, Paul, Ahuva Nissim, Brent J. Ryan, Matthew Whiteman, & Paul G. Winyard. (2012). Detection and isolation of human serum autoantibodies that recognize oxidatively modified autoantigens. Free Radical Biology and Medicine. 57. 79–91. 20 indexed citations

20.

Tarr, Joanna M., Paul G. Winyard, Brent J. Ryan, et al.. (2010). Extracellular calreticulin is present in the joints of patients with rheumatoid arthritis and inhibits FasL (CD95L)–mediated apoptosis of T cells. Arthritis & Rheumatism. 62(10). 2919–2929. 48 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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