Bradford B. Lowell

66.0k total citations · 35 hit papers
200 papers, 50.5k citations indexed

About

Bradford B. Lowell is a scholar working on Physiology, Endocrine and Autonomic Systems and Molecular Biology. According to data from OpenAlex, Bradford B. Lowell has authored 200 papers receiving a total of 50.5k indexed citations (citations by other indexed papers that have themselves been cited), including 111 papers in Physiology, 100 papers in Endocrine and Autonomic Systems and 60 papers in Molecular Biology. Recurrent topics in Bradford B. Lowell's work include Adipose Tissue and Metabolism (98 papers), Regulation of Appetite and Obesity (85 papers) and Biochemical Analysis and Sensing Techniques (52 papers). Bradford B. Lowell is often cited by papers focused on Adipose Tissue and Metabolism (98 papers), Regulation of Appetite and Obesity (85 papers) and Biochemical Analysis and Sensing Techniques (52 papers). Bradford B. Lowell collaborates with scholars based in United States, United Kingdom and Germany. Bradford B. Lowell's co-authors include Jeffrey S. Flier, Bruce M. Spiegelman, Gerald I. Shulman, Joel K. Elmquist, Chen‐Yu Zhang, Eleftheria Maratos–Flier, A. Hamann, Linh Vong, Pere Puigserver and Zhidan Wu and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Bradford B. Lowell

197 papers receiving 49.6k citations

Hit Papers

Mechanisms Controlling Mi... 1993 2026 2004 2015 1999 1996 2002 2005 1995 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1
    1999 3.4k citations Saverio Cinti, Bradford B. Lowell et al. profile →
  2. Role of leptin in the neuroendocrine response to fasting
    1996 2.6k citations Bradford B. Lowell, Jeffrey S. Flier et al. Nature profile →
  3. Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres
    2002 2.1k citations Bradford B. Lowell et al. Nature profile →
  4. Mitochondrial Dysfunction and Type 2 Diabetes
    2005 1.6k citations Bradford B. Lowell, Gerald I. Shulman Science profile →
  5. Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action
    1995 1.4k citations A. Hamann, Bradford B. Lowell et al. profile →
  6. Towards a molecular understanding of adaptive thermogenesis
    2000 1.3k citations Bradford B. Lowell et al. Nature profile →
  7. Rapid, reversible activation of AgRP neurons drives feeding behavior in mice
    2011 1.1k citations Michael J. Krashes, Bradford B. Lowell et al. Journal of Clinical Investigation profile →
  8. Neuron-type-specific signals for reward and punishment in the ventral tegmental area
    2012 946 citations Bradford B. Lowell et al. Nature profile →
  9. Leptin Action on GABAergic Neurons Prevents Obesity and Reduces Inhibitory Tone to POMC Neurons
    2011 910 citations Chianping Ye, Streamson C. Chua et al. Neuron profile →
  10. Mice lacking melanin-concentrating hormone are hypophagic and lean
    1998 910 citations Nicholas A. Tritos, Bradford B. Lowell et al. Nature profile →
  11. Development of obesity in transgenic mice after genetic ablation of brown adipose tissue
    1993 881 citations Bradford B. Lowell, A. Hamann et al. Nature profile →
  12. Divergence of Melanocortin Pathways in the Control of Food Intake and Energy Expenditure
    2005 868 citations Nina Balthasar, Louise T. Dalgaard et al. profile →
  13. Uncoupling Protein-2 Negatively Regulates Insulin Secretion and Is a Major Link between Obesity, β Cell Dysfunction, and Type 2 Diabetes
    2001 773 citations Chenyu Zhang, Stefan Krauß et al. profile →
  14. Dentate Gyrus NMDA Receptors Mediate Rapid Pattern Separation in the Hippocampal Network
    2007 737 citations Thomas J. McHugh, Matthew W. Jones et al. Science profile →
  15. Leptin Receptor Signaling in POMC Neurons Is Required for Normal Body Weight Homeostasis
    2004 729 citations Nina Balthasar, Roberto Coppari et al. Neuron profile →
  16. Multiple Cytokines and Acute Inflammation Raise Mouse Leptin Levels: Potential Role in Inflammatory Anorexia
    1997 657 citations Jeffrey S. Flier, Bradford B. Lowell et al. profile →
  17. Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.
    1998 640 citations Bradford B. Lowell et al. Journal of Clinical Investigation profile →
  18. Adipose tissue mass can be regulated through the vasculature
    2002 639 citations Bradford B. Lowell et al. Proceedings of the National Academy of Sciences profile →
  19. βAR Signaling Required for Diet-Induced Thermogenesis and Obesity Resistance
    2002 629 citations Harveen Dhillon, Saverio Cinti et al. Science profile →
  20. Leptin Directly Activates SF1 Neurons in the VMH, and This Action by Leptin Is Required for Normal Body-Weight Homeostasis
    2006 629 citations Harveen Dhillon, Jeffrey M. Zigman et al. Neuron profile →
  21. UCP3: An Uncoupling Protein Homologue Expressed Preferentially and Abundantly in Skeletal Muscle and Brown Adipose Tissue
    1997 628 citations Antonio Vidal‐Puig, Danica Grujić et al. profile →
  22. Cytokine Stimulation of Energy Expenditure through p38 MAP Kinase Activation of PPARγ Coactivator-1
    2001 620 citations Stefan Krauß, Bradford B. Lowell et al. profile →
  23. Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance
    2000 612 citations Bradford B. Lowell et al. profile →
  24. BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis
    2003 581 citations Luca Scorrano, Stefan Krauß et al. Nature profile →
  25. Energy Metabolism in Uncoupling Protein 3 Gene Knockout Mice
    2000 564 citations Antonio Vidal‐Puig, Danica Grujić et al. Journal of Biological Chemistry profile →
  26. A molecular census of arcuate hypothalamus and median eminence cell types
    2017 560 citations John N. Campbell, Jon M. Resch et al. profile →
  27. Regulation of PPAR gamma gene expression by nutrition and obesity in rodents.
    1996 558 citations Antonio Vidal‐Puig, Bradford B. Lowell et al. Journal of Clinical Investigation profile →
  28. The mitochondrial uncoupling-protein homologues
    2005 551 citations Stefan Krauß, Bradford B. Lowell et al. profile →
  29. Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity
    2007 549 citations Roberto Coppari, Nina Balthasar et al. Nature profile →
  30. Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance
    2008 533 citations Joel K. Elmquist, Bradford B. Lowell et al. profile →
  31. Melanocortin-4 Receptors Expressed by Cholinergic Neurons Regulate Energy Balance and Glucose Homeostasis
    2011 481 citations Nina Balthasar, Charlotte E. Lee et al. Cell Metabolism profile →
  32. An excitatory paraventricular nucleus to AgRP neuron circuit that drives hunger
    2014 473 citations Michael J. Krashes, Joseph C. Madara et al. Nature profile →
  33. Sensory Neurons that Detect Stretch and Nutrients in the Digestive System
    2016 461 citations Bradford B. Lowell et al. profile →
  34. Identification of Spinal Circuits Transmitting and Gating Mechanical Pain
    2014 405 citations Michael J. Krashes, Bradford B. Lowell et al. profile →
  35. Toward a Wiring Diagram Understanding of Appetite Control
    2017 384 citations Mark L. Andermann, Bradford B. Lowell Neuron profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Bradford B. Lowell United States 106 24.2k 18.9k 16.4k 9.7k 8.3k 200 50.5k
Michael W. Schwartz United States 111 19.1k 0.8× 27.5k 1.5× 7.3k 0.4× 13.6k 1.4× 7.6k 0.9× 291 45.7k
Joel K. Elmquist United States 105 13.9k 0.6× 28.4k 1.5× 7.0k 0.4× 12.3k 1.3× 5.7k 0.7× 228 43.6k
Jeffrey M. Friedman United States 87 21.1k 0.9× 28.4k 1.5× 11.5k 0.7× 16.0k 1.7× 15.8k 1.9× 209 53.0k
Stephen C. Woods United States 106 16.9k 0.7× 23.2k 1.2× 6.3k 0.4× 11.1k 1.1× 4.9k 0.6× 455 41.3k
Randy J. Seeley United States 97 16.6k 0.7× 20.3k 1.1× 5.9k 0.4× 10.4k 1.1× 5.2k 0.6× 413 37.9k
Tamás L. Horváth United States 97 11.9k 0.5× 15.8k 0.8× 8.2k 0.5× 7.0k 0.7× 3.8k 0.5× 328 34.7k
Masashi Yanagisawa Japan 116 27.6k 1.1× 19.4k 1.0× 18.7k 1.1× 3.1k 0.3× 2.1k 0.3× 527 64.7k
Matthias H. Tschöp United States 88 15.8k 0.7× 17.5k 0.9× 6.1k 0.4× 10.1k 1.0× 5.3k 0.6× 303 33.6k
Rexford S. Ahima United States 80 13.8k 0.6× 13.9k 0.7× 6.9k 0.4× 6.2k 0.6× 10.4k 1.3× 238 32.2k
Stephen R. Bloom United Kingdom 137 23.5k 1.0× 28.8k 1.5× 19.6k 1.2× 15.1k 1.6× 7.6k 0.9× 1.1k 79.9k

Countries citing papers authored by Bradford B. Lowell

Since Specialization
Citations

This map shows the geographic impact of Bradford B. Lowell's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bradford B. Lowell with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bradford B. Lowell more than expected).

Fields of papers citing papers by Bradford B. Lowell

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bradford B. Lowell. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bradford B. Lowell. The network helps show where Bradford B. Lowell may publish in the future.

Co-authorship network of co-authors of Bradford B. Lowell

This figure shows the co-authorship network connecting the top 25 collaborators of Bradford B. Lowell. A scholar is included among the top collaborators of Bradford B. Lowell based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Bradford B. Lowell. Bradford B. Lowell is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Zhang, Stephen X., Angela Kim, Joseph C. Madara, et al.. (2024). Stochastic neuropeptide signals compete to calibrate the rate of satiation. Nature. 637(8044). 137–144. 12 indexed citations
2.
Araújo, Ivan E. de, Jamy D. Ard, John F. Cryan, et al.. (2023). The Neurobiology of Eating Behavior in Obesity: Mechanisms and Therapeutic Targets: A Report from the 23rd Annual Harvard Nutrition Obesity Symposium. American Journal of Clinical Nutrition. 118(1). 314–328. 7 indexed citations
3.
Luca, Roberto De, Stefano Nardone, Kevin P. Grace, et al.. (2022). Orexin neurons inhibit sleep to promote arousal. Nature Communications. 13(1). 4163–4163. 55 indexed citations
4.
Luca, Roberto De, Stefano Nardone, Kevin P. Grace, et al.. (2022). Orexin neurons inhibit sleep to promote arousal. Zenodo (CERN European Organization for Nuclear Research). 1 indexed citations
5.
Gupta, Abhishek, Shakun Karki, Sukanta Jash, et al.. (2022). Human CIDEC transgene improves lipid metabolism and protects against high-fat diet–induced glucose intolerance in mice. Journal of Biological Chemistry. 298(9). 102347–102347. 17 indexed citations
6.
Kim, Angela, Joseph C. Madara, Chen Wu, Mark L. Andermann, & Bradford B. Lowell. (2021). Neural basis for regulation of vasopressin secretion by anticipated disturbances in osmolality. eLife. 10. 15 indexed citations
7.
Li, Monica M., Joseph C. Madara, Jennifer S. Steger, et al.. (2019). The Paraventricular Hypothalamus Regulates Satiety and Prevents Obesity via Two Genetically Distinct Circuits. Neuron. 102(3). 653–667.e6. 144 indexed citations
8.
Perry, Rachel J., Jon M. Resch, Amelia M Douglass, et al.. (2019). Leptin’s hunger-suppressing effects are mediated by the hypothalamic–pituitary–adrenocortical axis in rodents. Proceedings of the National Academy of Sciences. 116(27). 13670–13679. 65 indexed citations
9.
Mochizuki, Takatoshi, Elda Arrigoni, Jacob Marcus, et al.. (2011). Orexin receptor 2 expression in the posterior hypothalamus rescues sleepiness in narcoleptic mice. Proceedings of the National Academy of Sciences. 108(11). 4471–4476. 105 indexed citations
10.
Xu, Yong, Jennifer W. Hill, Makoto Fukuda, et al.. (2010). PI3K Signaling in the Ventromedial Hypothalamic Nucleus Is Required for Normal Energy Homeostasis. Cell Metabolism. 12(1). 88–95. 91 indexed citations
11.
Pol, Anthony N. van den, Yang Yao, Liying Fu, et al.. (2009). Neuromedin B and Gastrin-Releasing Peptide Excite Arcuate Nucleus Neuropeptide Y Neurons in a Novel Transgenic Mouse Expressing StrongRenillaGreen Fluorescent Protein in NPY Neurons. Journal of Neuroscience. 29(14). 4622–4639. 186 indexed citations
12.
McHugh, Thomas J., Matthew W. Jones, Jennifer J. Quinn, et al.. (2007). Dentate Gyrus NMDA Receptors Mediate Rapid Pattern Separation in the Hippocampal Network. Science. 317(5834). 94–99. 737 indexed citations breakdown →
13.
Dhillon, Harveen, Jeffrey M. Zigman, Chianping Ye, et al.. (2006). Leptin Directly Activates SF1 Neurons in the VMH, and This Action by Leptin Is Required for Normal Body-Weight Homeostasis. Neuron. 49(2). 191–203. 629 indexed citations breakdown →
14.
Krauß, Stefan, Chenyu Zhang, Luca Scorrano, et al.. (2003). Superoxide-mediated activation of uncoupling protein 2 causes pancreatic β cell dysfunction. Journal of Clinical Investigation. 112(12). 1831–1842. 272 indexed citations
15.
Krauß, Stefan, Chenyu Zhang, Luca Scorrano, et al.. (2003). Superoxide-mediated activation of uncoupling protein 2 causes pancreatic β cell dysfunction. Journal of Clinical Investigation. 112(12). 1831–1842. 296 indexed citations
16.
Krauß, Stefan, Chenyu Zhang, & Bradford B. Lowell. (2001). A significant portion of mitochondrial proton leak in intact thymocytes depends on expression of UCP2. Proceedings of the National Academy of Sciences. 99(1). 118–122. 152 indexed citations
17.
Ludwig, David S., Nicholas A. Tritos, Jason Mastaitis, et al.. (2001). Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance. Journal of Clinical Investigation. 107(3). 379–386. 486 indexed citations
18.
Valet, Philippe, Danica Grujić, Jennifer M. Wade, et al.. (2000). Expression of Human α2-Adrenergic Receptors in Adipose Tissue of β3-Adrenergic Receptor-deficient Mice Promotes Diet-induced Obesity. Journal of Biological Chemistry. 275(44). 34797–34802. 80 indexed citations
19.
Vidal‐Puig, Antonio, et al.. (1999). Effects of Obesity and Stable Weight Reduction on UCP2 and UCP3 Gene Expression in Humans. Obesity Research. 7(2). 133–140. 55 indexed citations
20.
Lowell, Bradford B., Vedrana S. Susulic, A. Hamann, et al.. (1993). Development of morbid obesity in transgenic mice following the genetic ablation of brown adipose tissue. Clinical research. 41(2). 260. 8 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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