Barbara L. Gaffney

5.0k citations

80 papers · 4.2k indexed · 2 hit papers · h-index 31

Co-authors: Roger A. Jones Dinshaw J. Patel Artem A. Serganov Winfried Barchet Manuel Ascano Thomas Zillinger Pu Gao Thomas Tuschl
Topics: DNA and Nucleic Acid Chemistry (44 papers)Advanced biosensing and bioanalysis techniques (25 papers)RNA and protein synthesis mechanisms (24 papers)
Cited by: Virology Immunology Infectious Diseases
Journals: Science Cell Proceedings of the National Academy of Sciences
Partner nations: United States Germany Netherlands

In The Last Decade

Barbara L. Gaffney

79 papers receiving 4.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase

2013 836 citations Pu Gao, Manuel Ascano et al. Cell profile →
Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA

2013 457 citations Pu Gao, Manuel Ascano et al. Cell profile →

Peers

Countries citing papers authored by Barbara L. Gaffney

Since Specialization

Citations

This map shows the geographic impact of Barbara L. Gaffney's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Barbara L. Gaffney with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Barbara L. Gaffney more than expected).

Fields of papers citing papers by Barbara L. Gaffney

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Barbara L. Gaffney. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Barbara L. Gaffney. The network helps show where Barbara L. Gaffney may publish in the future.

Co-authorship network of co-authors of Barbara L. Gaffney

This figure shows the co-authorship network connecting the top 25 collaborators of Barbara L. Gaffney. A scholar is included among the top collaborators of Barbara L. Gaffney based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Barbara L. Gaffney. Barbara L. Gaffney is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	One‐Flask Synthesis of Cyclic Diguanosine Monophosphate (c‐di‐GMP) 2023 ·Current Protocols ·Barbara L. Gaffney,Roger A. Jones	1
2	Synthesis of Capped RNA using a DMT Group as a Purification Handle 2014 ·Nucleosides Nucleotides & Nucleic Acids ·Elizabeth Veliath,Barbara L. Gaffney,Roger A. Jones	7
3	Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAAbreakdown → 2013 ·Cell ·Pu Gao,Manuel Ascano,Thomas Zillinger,Weiyi Wang,Peihong Dai,Artem A. Serganov,Barbara L. Gaffney,Stewart Shuman,Roger A. Jones,Liang Deng,Gunther Hartmann,Winfried Barchet,Thomas Tuschl,Dinshaw J. Patel	457
4	Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthasebreakdown → 2013 ·Cell ·Pu Gao,Manuel Ascano,Yang Wu,Winfried Barchet,Barbara L. Gaffney,Thomas Zillinger,Artem A. Serganov,Yizhou Liu,Roger A. Jones,Gunther Hartmann,Thomas Tuschl,Dinshaw J. Patel	836
5	Identification of c-di-GMP Derivatives Resistant to an EAL Domain Phosphodiesterase 2012 ·Biochemistry ·(unknown),Barbara L. Gaffney,Roger A. Jones,Scott A. Strobel	28
6	Differential Analogue Binding by Two Classes of c-di-GMP Riboswitches 2011 ·Journal of the American Chemical Society ·(unknown),Barbara L. Gaffney,Roger A. Jones,Scott A. Strobel	55
7	Structural basis of HIV-1 resistance to AZT by excision 2010 ·Nature Structural & Molecular Biology ·(unknown),Kalyan Das,(unknown),Joseph D. Bauman,Arthur D. Clark,Xiaorong Hou,Yulia Volovik Frenkel,Barbara L. Gaffney,Roger A. Jones,Paul L. Boyer,Stephen H. Hughes,Stefan G. Sarafianos,Eddy Arnold	95
8	Structural Basis for the Role of the K65R Mutation in HIV-1 Reverse Transcriptase Polymerization, Excision Antagonism, and Tenofovir Resistance 2009 ·Journal of Biological Chemistry ·Kalyan Das,Rajiv P. Bandwar,Kirsten White,Joy Y. Feng,Stefan G. Sarafianos,Steven Tuske,(unknown),Arthur D. Clark,Paul L. Boyer,Xiaorong Hou,Barbara L. Gaffney,Roger A. Jones,Michael D. Miller,Stephen H. Hughes,Eddy Arnold	71
9	Synthesis of Guanosine and Deoxyguanosine Phosphoramidites with Cross-Linkable Thioalkyl Tethers for Direct Incorporation into RNA and DNA 2009 ·Nucleosides Nucleotides & Nucleic Acids ·Xiaorong Hou,Gang Wang,Barbara L. Gaffney,Roger A. Jones	7
10	Thiophosphate Analogs of c-di-GMP: Impact on Polymorphism 2009 ·Nucleosides Nucleotides & Nucleic Acids ·Jianwei Zhao,Elizabeth Veliath,Seho Kim,Barbara L. Gaffney,Roger A. Jones	15
11	One-Flask Synthesis of Dinucleoside Tetra- and Pentaphosphates 2006 ·Organic Letters ·(unknown),Barbara L. Gaffney,Roger A. Jones	27
12	A glutamate‐alanine‐leucine (EAL) domain protein of Salmonella controls bacterial survival in mice, antioxidant defence and killing of macrophages: role of cyclic diGMP 2005 ·Molecular Microbiology ·Katherine B. Hisert,Michael J. MacCoss,Michael U. Shiloh,K. Heran Darwin,Shaneen Singh,Roger A. Jones,Sabine Ehrt,Zhaoying Zhang,Barbara L. Gaffney,Sheetal Gandotra,David W. Holden,Diana Murray,Carl Nathan	116
13	Differential Binding of Mg ²⁺ , Zn ²⁺ , and Cd ²⁺ at Two Sites in a Hammerhead Ribozyme Motif, Determined by ¹⁵ N NMR 2004 ·Journal of the American Chemical Society ·Gang Wang,Barbara L. Gaffney,Roger A. Jones	26
14	High yield protection of purine ribonucleosides for phosphoramidite RNA synthesis 1999 ·Tetrahedron Letters ·Quanlai Song,Weimin Wang,(unknown),Xiaohu Zhang,Barbara L. Gaffney,Roger A. Jones	19
15	Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative 1995 ·Biochemistry ·Gary N. Parkinson,(unknown),(unknown),Stephan L. Ginell,Roger A. Jones,Barbara L. Gaffney,Helen M. Berman	20
16	Structure of a new crystal form of a DNA dodecamer containing T.cntdot.(O6Me)G base pairs 1995 ·Biochemistry ·J. Vojtěchovský,(unknown),Barbara L. Gaffney,Roger A. Jones,Helen M. Berman	12
17	Crystal Structure of a Mispaired Dodecamer, d(CGAGAATTC(O6Me)GCG)2, Containing a Carcinogenic O6-Methylguanine 1994 ·Biochemistry ·Stephan L. Ginell,J. Vojtěchovský,Barbara L. Gaffney,Roger A. Jones,Helen M. Berman	9
18	Crystal and molecular structure of a DNA fragment containing a 2-aminoadenine modification: the relationship between conformation, packing, and hydration in Z-DNA hexamers 1992 ·Biochemistry ·Bohdan Schneider,Stephan L. Ginell,Roger A. Jones,Barbara L. Gaffney,Helen M. Berman	28
19	Thermodynamic comparison of the base pairs formed by the carcinogenic lesion O6-methylguanine with reference both to Watson-Crick pairs and to mismatched pairs 1989 ·Biochemistry ·Barbara L. Gaffney,Roger A. Jones	100
20	Methylation of thymine residues during oligonucleotide synthesis 1985 ·Nucleic Acids Research ·Xiang Gao,Barbara L. Gaffney,M. Senior,(unknown),Roger A. Jones	36

About Barbara L. Gaffney

Barbara L. Gaffney is a scholar working on Microbiology, Virology and Molecular Biology, having authored 80 papers that have together received 4.2k indexed citations. Recurring topics across this work include DNA and Nucleic Acid Chemistry (44 papers), Advanced biosensing and bioanalysis techniques (25 papers) and RNA and protein synthesis mechanisms (24 papers). The work is most often cited by research in Virology (302 citations), Immunology (1.3k citations) and Infectious Diseases (1.1k citations). Barbara L. Gaffney has collaborated with scholars based in United States, Germany and Netherlands. Frequent co-authors include Roger A. Jones, Dinshaw J. Patel, Artem A. Serganov, Winfried Barchet, Manuel Ascano, Thomas Zillinger, Pu Gao, Thomas Tuschl, Gunther Hartmann and Yizhou Liu. Their work appears in journals such as Science, Cell and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact