Arnim Pause

19.9k total citations · 7 hit papers
79 papers, 10.6k citations indexed

About

Arnim Pause is a scholar working on Molecular Biology, Cancer Research and Epidemiology. According to data from OpenAlex, Arnim Pause has authored 79 papers receiving a total of 10.6k indexed citations (citations by other indexed papers that have themselves been cited), including 58 papers in Molecular Biology, 19 papers in Cancer Research and 15 papers in Epidemiology. Recurrent topics in Arnim Pause's work include RNA and protein synthesis mechanisms (19 papers), Cancer, Hypoxia, and Metabolism (16 papers) and RNA Research and Splicing (15 papers). Arnim Pause is often cited by papers focused on RNA and protein synthesis mechanisms (19 papers), Cancer, Hypoxia, and Metabolism (16 papers) and RNA Research and Splicing (15 papers). Arnim Pause collaborates with scholars based in Canada, United States and United Kingdom. Arnim Pause's co-authors include Nahum Sonenberg, Graham J. Belsham, Tai-An Lin, John C. Lawrence, Anne‐Claude Gingras, Richard D. Klausner, Nathalie Méthot, Yuri V. Svitkin, Ashkan Haghighat and Stephen Lee and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Arnim Pause

77 papers receiving 10.4k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

1994 1.0k citations Arnim Pause, Graham J. Belsham et al. Nature profile →
mTORC1 Controls Mitochondrial Activity and Biogenesis through 4E-BP-Dependent Translational Regulation

2013 614 citations Simon‐Pierre Gravel, Valérie Chénard et al. profile →
PHAS-I as a Link Between Mitogen-Activated Protein Kinase and Translation Initiation

1994 594 citations Tai-An Lin, Arnim Pause et al. Science profile →
The Translation Initiation Factor eIF-4E Binds to a Common Motif Shared by the Translation Factor eIF-4γ and the Translational Repressors 4E-Binding Proteins

1995 569 citations Arnim Pause, Nahum Sonenberg et al. profile →
Mutational analysis of a DEAD box RNA helicase: the mammalian translation initiation factor eIF-4A.

1992 543 citations Arnim Pause, Nahum Sonenberg profile →
Repression of cap-dependent translation by 4E-binding protein 1: competition with p220 for binding to eukaryotic initiation factor-4E.

1995 515 citations Arnim Pause, Nahum Sonenberg et al. profile →
AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species

2017 428 citations Bożena Samborska, Brandon Faubert et al. Cell Reports profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author						Papers	Cites
Arnim Pause	8.2k	1.9k	1.2k	885	859	79	10.6k
Sylvain Meloche	7.3k 0.9×	1.3k 0.7×	649 0.5×	1.9k 2.2×	1.2k 1.4×	151	10.6k
Ivan Topisirović	7.7k 0.9×	1.4k 0.7×	812 0.7×	960 1.1×	210 0.2×	111	9.6k
Tsonwin Hai	6.3k 0.8×	1.1k 0.6×	1.2k 1.0×	990 1.1×	419 0.5×	70	10.0k
Lihua Julie Zhu	6.8k 0.8×	1.2k 0.7×	734 0.6×	790 0.9×	197 0.2×	165	9.3k
Maria Hatzoglou	5.4k 0.7×	1.1k 0.6×	1.1k 0.9×	530 0.6×	444 0.5×	114	7.9k
Mary E. Gerritsen	4.1k 0.5×	1.6k 0.9×	397 0.3×	1.2k 1.4×	445 0.5×	122	8.5k
Leon O. Murphy	6.6k 0.8×	1.4k 0.7×	1.8k 1.5×	1.2k 1.4×	148 0.2×	31	9.3k
Annik Prat	2.8k 0.3×	1.5k 0.8×	570 0.5×	775 0.9×	522 0.6×	101	8.3k
Christian Rommel	7.3k 0.9×	913 0.5×	516 0.4×	1.7k 1.9×	276 0.3×	88	10.2k
John David Dignam	10.2k 1.2×	1.9k 1.0×	799 0.7×	2.0k 2.3×	593 0.7×	46	14.2k

Countries citing papers authored by Arnim Pause

Since Specialization

Citations

This map shows the geographic impact of Arnim Pause's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Arnim Pause with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Arnim Pause more than expected).

Fields of papers citing papers by Arnim Pause

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Arnim Pause. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Arnim Pause. The network helps show where Arnim Pause may publish in the future.

Co-authorship network of co-authors of Arnim Pause

This figure shows the co-authorship network connecting the top 25 collaborators of Arnim Pause. A scholar is included among the top collaborators of Arnim Pause based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Arnim Pause. Arnim Pause is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Dunlop, Elaine A., Peter F. Doubleday, Tijs Claessens, et al.. (2025). Characterizing the tumor suppressor activity of FLCN in Birt-Hogg-Dubé syndrome cell models through transcriptomic and proteomic analysis. Oncogene. 44(23). 1833–1843. 1 indexed citations

Martin, Claire E., Dmitri Kharitidi, Pirjo M. Apaja, et al.. (2021). Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes. iScience. 24(11). 103274–103274. 7 indexed citations

Morales, Daniel, Halil Bagci, Avihu Klar, et al.. (2019). The endosomal sorting adaptor HD-PTP is required for ephrin-B:EphB signalling in cellular collapse and spinal motor axon guidance. Scientific Reports. 9(1). 11945–11945. 16 indexed citations

Paquette, Mathieu, Leeanna El–Houjeiri, & Arnim Pause. (2018). mTOR Pathways in Cancer and Autophagy. Cancers. 10(1). 18–18. 244 indexed citations

Samborska, Bożena, Brandon Faubert, H. Eric, et al.. (2017). AMPK Maintains Cellular Metabolic Homeostasis through Regulation of Mitochondrial Reactive Oxygen Species. Cell Reports. 21(1). 1–9. 428 indexed citations breakdown →

Yan, Ming, Étienne Audet‐Walsh, Sanaz Manteghi, et al.. (2016). Chronic AMPK activation via loss of FLCN induces functional beige adipose tissue through PGC-1α/ERRα. Genes & Development. 30(9). 1034–1046. 86 indexed citations

Kharitidi, Dmitri, Pirjo M. Apaja, Sanaz Manteghi, et al.. (2015). Interplay of Endosomal pH and Ligand Occupancy in Integrin α5β1 Ubiquitination, Endocytic Sorting, and Cell Migration. Cell Reports. 13(3). 599–609. 52 indexed citations

Possik, Elite, Sanaz Manteghi, Marie‐Claude Gingras, et al.. (2015). FLCN and AMPK Confer Resistance to Hyperosmotic Stress via Remodeling of Glycogen Stores. PLoS Genetics. 11(10). e1005520–e1005520. 40 indexed citations

Possik, Elite, Zahra Jalali, Yann Nouët, et al.. (2014). Folliculin Regulates Ampk-Dependent Autophagy and Metabolic Stress Survival. PLoS Genetics. 10(4). e1004273–e1004273. 78 indexed citations

10.

Fonseca, Bruno D., et al.. (2014). The ever-evolving role of mTOR in translation. Seminars in Cell and Developmental Biology. 36. 102–112. 66 indexed citations

11.

Uniacke, James, Chet E. Holterman, Gabriel Lachance, et al.. (2012). An oxygen-regulated switch in the protein synthesis machinery. Nature. 486(7401). 126–129. 255 indexed citations

12.

Philp, Andrew, Tijs Claessens, Lieke Gijezen, et al.. (2010). Absence of the Birt–Hogg–Dubé gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility. Oncogene. 30(10). 1159–1173. 50 indexed citations

13.

Gingras, Marie‐Claude, Yu Ling Zhang, Dmitri Kharitidi, et al.. (2009). HD-PTP Is a Catalytically Inactive Tyrosine Phosphatase Due to a Conserved Divergence in Its Phosphatase Domain. PLoS ONE. 4(4). e5105–e5105. 44 indexed citations

14.

Gingras, Marie‐Claude, Dmitri Kharitidi, Valérie Chénard, et al.. (2009). Expression analysis and essential role of the putative tyrosine phosphatase His-domain-containing protein tyrosine phosphatase (HD-PTP). The International Journal of Developmental Biology. 53(7). 1069–1074. 27 indexed citations

15.

Khacho, Mireille, et al.. (2008). eEF1A Is a Novel Component of the Mammalian Nuclear Protein Export Machinery. Molecular Biology of the Cell. 19(12). 5296–5308. 78 indexed citations

16.

Fournier, Marie-Christine, et al.. (2001). Role of transforming growth factor-α in von Hippel– Lindau\n (VHL)−/− clear cell renal carcinoma cell proliferation: A\n possible mechanism coupling VHL tumor suppressor inactivation and tumorigenesis. Europe PMC (PubMed Central). 34 indexed citations

17.

Thibeault, Diane, Roger Maurice, Louise Pilote, Daniel Lamarre, & Arnim Pause. (2001). In Vitro Characterization of a Purified NS2/3 Protease Variant of Hepatitis C Virus. Journal of Biological Chemistry. 276(49). 46678–46684. 44 indexed citations

18.

Pause, Arnim, Teijiro Aso, W. Marston Linehan, et al.. (1996). Interaction of von Hippel-Lindau tumor suppressor gene product with elongin. Methods in enzymology on CD-ROM/Methods in enzymology. 274. 436–441. 7 indexed citations

19.

Duan, Delin, Arnim Pause, Wilson H. Burgess, et al.. (1995). Inhibition of Transcription Elongation by the VHL Tumor Suppressor Protein. Science. 269(5229). 1402–1406. 472 indexed citations

20.

Pause, Arnim, Graham J. Belsham, Anne‐Claude Gingras, et al.. (1994). Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function. Nature. 371(6500). 762–767. 1039 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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