April D. Lake

1.6k citations

23 papers · 1.3k indexed · h-index 17

Epidemiology top 5%
Molecular Biology
Oncology top 10%
Hepatology top 5%
Endocrinology, Diabetes and Metabolism top 5%

Co-authors: Nathan J. Cherrington Rhiannon N. Hardwick Petr Novák Mark J. Canet John Clarke Craig D. Fisher Lois D. Lehman‐McKeeman Michael D. Reily
Topics: Liver Disease Diagnosis and Treatment (18 papers)Drug Transport and Resistance Mechanisms (10 papers)Liver Diseases and Immunity (8 papers)
Cited by: Hepatology Epidemiology Pharmacology
Journals: Journal of Hepatology Journal of Pharmacology and Experimental Therapeutics Biochemical Pharmacology
Partner nations: United States Czechia Germany

In The Last Decade

April D. Lake

23 papers receiving 1.3k citations

Peers

Countries citing papers authored by April D. Lake

Since Specialization

Citations

This map shows the geographic impact of April D. Lake's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by April D. Lake with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites April D. Lake more than expected).

Fields of papers citing papers by April D. Lake

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by April D. Lake. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by April D. Lake. The network helps show where April D. Lake may publish in the future.

Co-authorship network of co-authors of April D. Lake

This figure shows the co-authorship network connecting the top 25 collaborators of April D. Lake. A scholar is included among the top collaborators of April D. Lake based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with April D. Lake. April D. Lake is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Neurotoxicity of an Hepatitis B Virus (HBV) Transcript Inhibitor in 13-Week Rat and Monkey Studies 2022 ·Toxicological Sciences ·April D. Lake,(unknown),(unknown),Joseph C. Arezzo,Ricardo Ramírez,(unknown),Yu Mei,Dylan M. Glatt,Ryan A. Dick,Xiaodong Xie,Regina Choy,Guofeng Cheng,(unknown),Anne Chester,Darryl Kato,Leigh Ann Burns‐Naas	8
2	Folate receptor-beta expression as a diagnostic target in human & rodent nonalcoholic steatohepatitis 2019 ·Toxicology and Applied Pharmacology ·April D. Lake,Rhiannon N. Hardwick,Christopher P. Leamon,Philip S. Low,Nathan J. Cherrington	4
3	Impaired N‐linked glycosylation of uptake and efflux transporters in human non‐alcoholic fatty liver disease 2017 ·Liver International ·John Clarke,Petr Novák,April D. Lake,Rhiannon N. Hardwick,Nathan J. Cherrington	67
4	Transcription factor binding site enrichment analysis predicts drivers of altered gene expression in nonalcoholic steatohepatitis 2016 ·Biochemical Pharmacology ·April D. Lake,(unknown),Petr Novák,Nathan J. Cherrington,Catharine L. Smith	15
5	Dose and Effect Thresholds for Early Key Events in a PPARα-Mediated Mode of Action 2015 ·Toxicological Sciences ·April D. Lake,Charles E. Wood,Virunya S. Bhat,Brian N. Chorley,Gleta Carswell,(unknown),Elaina M. Kenyon,Beth Padnos,Tanya Moore,Alan H. Tennant,Judith E. Schmid,Barbara Jane George,David Gaddis Ross,Michael F. Hughes,J. Christopher Corton,Jane Ellen Simmons,Charlene A. McQueen,Susan Hester	20
6	Increased Susceptibility to Methotrexate-Induced Toxicity in Nonalcoholic Steatohepatitis 2014 ·Toxicological Sciences ·Rhiannon N. Hardwick,John Clarke,April D. Lake,Mark J. Canet,Tarun Anumol,(unknown),Matthew D. Merrell,Michael Goedken,Shane A. Snyder,Nathan J. Cherrington	48
7	Experimental Nonalcoholic Steatohepatitis Increases Exposure to Simvastatin Hydroxy Acid by Decreasing Hepatic Organic Anion Transporting Polypeptide Expression 2014 ·Journal of Pharmacology and Experimental Therapeutics ·John Clarke,Rhiannon N. Hardwick,April D. Lake,Mark J. Canet,Nathan J. Cherrington	37
8	Modeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent Models 2014 ·Drug Metabolism and Disposition ·Mark J. Canet,Rhiannon N. Hardwick,April D. Lake,Anika L. Dzierlenga,John Clarke,Nathan J. Cherrington	57
9	Synergistic interaction between genetics and disease on pravastatin disposition 2014 ·Journal of Hepatology ·John Clarke,Rhiannon N. Hardwick,April D. Lake,Andrew J. Lickteig,Michael Goedken,Curtis D. Klaassen,Nathan J. Cherrington	45
10	Renal Xenobiotic Transporter Expression is Altered in Multiple Experimental Models of Nonalcoholic Steatohepatitis 2014 ·Drug Metabolism and Disposition ·Mark J. Canet,Rhiannon N. Hardwick,April D. Lake,Anika L. Dzierlenga,John Clarke,Michael Goedken,Nathan J. Cherrington	14
11	Branched chain amino acid metabolism profiles in progressive human nonalcoholic fatty liver disease 2014 ·Amino Acids ·April D. Lake,Petr Novák,Petia Shipkova,Nelly Aranı́bar,Donald G. Robertson,Michael D. Reily,Lois D. Lehman‐McKeeman,Richard R. Vaillancourt,Nathan J. Cherrington	181
12	The Adaptive Endoplasmic Reticulum Stress Response to Lipotoxicity in Progressive Human Nonalcoholic Fatty Liver Disease 2013 ·Toxicological Sciences ·April D. Lake,Petr Novák,Rhiannon N. Hardwick,(unknown),Fei Zhao,Walter T. Klimecki,Nathan J. Cherrington	106
13	Decreased hepatotoxic bile acid composition and altered synthesis in progressive human nonalcoholic fatty liver disease 2013 ·Toxicology and Applied Pharmacology ·April D. Lake,Petr Novák,Petia Shipkova,Nelly Aranı́bar,Donald G. Robertson,Michael D. Reily,Zhenqiang Lu,Lois D. Lehman‐McKeeman,Nathan J. Cherrington	158
14	Differential Regulation of Hepatic Organic Cation Transporter 1, Organic Anion-Transporting Polypeptide 1a4, Bile-Salt Export Pump, and Multidrug Resistance-Associated Protein 2 Transporter Expression in Lymphocyte-Deficient Mice Associates with Interleukin-6 Production 2013 ·Journal of Pharmacology and Experimental Therapeutics ·(unknown),Anika L. Dzierlenga,(unknown),R. M. Mulligan,April D. Lake,Nathan J. Cherrington,Susan C. McKarns	11
15	Characterization of Hepatocellular Carcinoma Related Genes and Metabolites in Human Nonalcoholic Fatty Liver Disease 2013 ·Digestive Diseases and Sciences ·John Clarke,Petr Novák,April D. Lake,Petia Shipkova,Nelly Aranı́bar,Donald G. Robertson,Paul Severson,Michael D. Reily,Bernard W. Futscher,Lois D. Lehman‐McKeeman,Nathan J. Cherrington	33
16	Altered UDP-Glucuronosyltransferase and Sulfotransferase Expression and Function during Progressive Stages of Human Nonalcoholic Fatty Liver Disease 2012 ·Drug Metabolism and Disposition ·Rhiannon N. Hardwick,(unknown),Vijay R. More,April D. Lake,Zhenqiang Lu,José E. Manautou,Angela L. Slitt,Nathan J. Cherrington	93
17	Altered Arsenic Disposition in Experimental Nonalcoholic Fatty Liver Disease 2012 ·Drug Metabolism and Disposition ·Mark J. Canet,Rhiannon N. Hardwick,April D. Lake,Michael J. Kopplin,George L. Scheffer,Walter T. Klimecki,A. Jay Gandolfi,Nathan J. Cherrington	21
18	Analysis of Global and Absorption, Distribution, Metabolism, and Elimination Gene Expression in the Progressive Stages of Human Nonalcoholic Fatty Liver Disease 2011 ·Drug Metabolism and Disposition ·April D. Lake,Petr Novák,Craig D. Fisher,Jonathan P. Jackson,Rhiannon N. Hardwick,Dean Billheimer,Walter T. Klimecki,Nathan J. Cherrington	124
19	Development of high-yield autofluorescent protein microarrays using hybrid cell-free expression with combined Escherichia coli S30 and wheat germ extracts 2010 ·Proteome Science ·Xristo Zárate,David C. Henderson,(unknown),April D. Lake,David W. Galbraith	16
20	Diversity in Antioxidant Response Enzymes in Progressive Stages of Human Nonalcoholic Fatty Liver Disease 2010 ·Drug Metabolism and Disposition ·Rhiannon N. Hardwick,Craig D. Fisher,Mark J. Canet,April D. Lake,Nathan J. Cherrington	151

About April D. Lake

April D. Lake is a scholar working on Hepatology, Epidemiology and Oncology, having authored 23 papers that have together received 1.3k indexed citations. Recurring topics across this work include Liver Disease Diagnosis and Treatment (18 papers), Drug Transport and Resistance Mechanisms (10 papers) and Liver Diseases and Immunity (8 papers). The work is most often cited by research in Hepatology (266 citations), Epidemiology (870 citations) and Pharmacology (160 citations). April D. Lake has collaborated with scholars based in United States, Czechia and Germany. Frequent co-authors include Nathan J. Cherrington, Rhiannon N. Hardwick, Petr Novák, Mark J. Canet, John Clarke, Craig D. Fisher, Lois D. Lehman‐McKeeman, Michael D. Reily, Petia Shipkova and Nelly Aranı́bar. Their work appears in journals such as Journal of Hepatology, Journal of Pharmacology and Experimental Therapeutics and Biochemical Pharmacology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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