Antonio Lavecchia

8.2k total citations · 4 hit papers
170 papers, 6.3k citations indexed

About

Antonio Lavecchia is a scholar working on Molecular Biology, Organic Chemistry and Pharmacology. According to data from OpenAlex, Antonio Lavecchia has authored 170 papers receiving a total of 6.3k indexed citations (citations by other indexed papers that have themselves been cited), including 122 papers in Molecular Biology, 46 papers in Organic Chemistry and 22 papers in Pharmacology. Recurrent topics in Antonio Lavecchia's work include Peroxisome Proliferator-Activated Receptors (37 papers), Synthesis and biological activity (16 papers) and Metabolism, Diabetes, and Cancer (15 papers). Antonio Lavecchia is often cited by papers focused on Peroxisome Proliferator-Activated Receptors (37 papers), Synthesis and biological activity (16 papers) and Metabolism, Diabetes, and Cancer (15 papers). Antonio Lavecchia collaborates with scholars based in Italy, Germany and India. Antonio Lavecchia's co-authors include Ettore Novellino, Carmen Di Giovanni, Carmen Cerchia, Fulvio Loiodice, Luciana Marinelli, Antonio Laghezza, Marino Artico, Paolo Tortorella, Romano Silvestri and Giuseppe La Regina and has published in prestigious journals such as Journal of the American Chemical Society, Journal of Biological Chemistry and SHILAP Revista de lepidopterología.

In The Last Decade

Antonio Lavecchia

166 papers receiving 6.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Machine-learning approaches in drug discovery: methods and applications

2014 521 citations Antonio Lavecchia Drug Discovery Today profile →
Virtual Screening Strategies in Drug Discovery: A Critical Review

2013 461 citations Antonio Lavecchia et al. profile →
Unleashing the power of generative AI in drug discovery

2024 64 citations Amit Gangwal, Antonio Lavecchia Drug Discovery Today profile →
Artificial intelligence in preclinical research: enhancing digital twins and organ-on-chip to reduce animal testing

2025 23 citations Amit Gangwal, Antonio Lavecchia Drug Discovery Today profile →

Peers

Countries citing papers authored by Antonio Lavecchia

Since Specialization

Citations

This map shows the geographic impact of Antonio Lavecchia's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Antonio Lavecchia with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Antonio Lavecchia more than expected).

Fields of papers citing papers by Antonio Lavecchia

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Antonio Lavecchia. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Antonio Lavecchia. The network helps show where Antonio Lavecchia may publish in the future.

Co-authorship network of co-authors of Antonio Lavecchia

This figure shows the co-authorship network connecting the top 25 collaborators of Antonio Lavecchia. A scholar is included among the top collaborators of Antonio Lavecchia based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Antonio Lavecchia. Antonio Lavecchia is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Artificial intelligence in anti-obesity drug discovery: unlocking next-generation therapeutics 2025 ·Drug Discovery Today ·Amit Gangwal, Antonio Lavecchia	3
2	Targeting RPSA to modulate endosomal trafficking and amyloidogenesis in genetic Alzheimer's disease 2025 ·Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ·(unknown), (unknown), Filomena Napolitano, (unknown), Giuseppina Minopoli, Silvia Bagnoli, Antonella Izzo, Simona Paladino, Benedetta Nacmias, Maria Antonietta De Matteis, Nunzia Montuori, Antonio Lavecchia, Daniela Sarnataro	1
3	Explainable Artificial Intelligence in Drug Discovery: Bridging Predictive Power and Mechanistic Insight 2025 ·Wiley Interdisciplinary Reviews Computational Molecular Science ·Antonio Lavecchia	1
4	Artificial intelligence in the development of small nucleic acid therapeutics: toward smarter and safer medicines 2025 ·Drug Discovery Today ·Pietro Delre, Carmen Cerchia, Antonio Lavecchia	0
5	A new potent and selective peroxisome proliferator-activated receptor alpha partial agonist displays anti-steatotic effects In vitro and behaves as a safe hypolipidemic and hypoglycemic agent in a diabetic mouse model 2025 ·European Journal of Medicinal Chemistry ·Antonio Laghezza, (unknown), Federica Gilardi, Aurélien Thomas, Leonardo Brunetti, (unknown), Luca Piemontese, Paolo Tortorella, (unknown), (unknown), Ashok Pattnaik, Venkatesan Jayaprakash, (unknown), (unknown), (unknown), Paolo Paoli, Fulvio Loiodice, Antonio Lavecchia	1
6	Secoiridoid-enriched extra virgin olive oil extracts enhance mitochondrial activity and antioxidant response in colorectal cancer cells: The role of Oleacein and Oleocanthal in PPARγ interaction 2025 ·Free Radical Biology and Medicine ·(unknown), (unknown), Giulia Lori, Pietro Delre, (unknown), (unknown), (unknown), Manuela Leri, (unknown), Ilario Losito, Tommaso R. I. Cataldi, Marzia Rossato, Vittorio Colantuoni, Maria Letizia Taddei, Antonio Lavecchia, Lina Sabatino	3
7	Synthesis and in vitro cytotoxicity of benzoxazole‐based PPARα/γ antagonists in colorectal cancer cell lines 2024 ·Archiv der Pharmazie ·(unknown), Antonio Laghezza, Carmen Cerchia, (unknown), (unknown), (unknown), (unknown), (unknown), Inmaculada Fernández, Fulvio Loiodice, Vadim S. Pokrovsky, Alessandra Ammazzalorso, Antonio Lavecchia	4
8	The Crosstalk between N-Formyl Peptide Receptors and uPAR in Systemic Sclerosis: Molecular Mechanisms, Pathogenetic Role and Therapeutic Opportunities 2024 ·International Journal of Molecular Sciences ·Filomena Napolitano, Francesca Wanda Rossi, Amato de Paulis, Antonio Lavecchia, Nunzia Montuori	1
9	Cladosporols and PPARγ: Same Gun, Same Bullet, More Targets 2024 ·Biomolecules ·(unknown), Antonella Mercuri, Sabrina Dallavalle, Salvatore Moricca, Antonio Lavecchia, Angelo Lupo	1
10	A New Antidiabetic Agent Showing Short- and Long-Term Effects Due to Peroxisome Proliferator-Activated Receptor Alpha/Gamma Dual Agonism and Mitochondrial Pyruvate Carrier Inhibition 2023 ·Journal of Medicinal Chemistry ·Antonio Laghezza, Carmen Cerchia, (unknown), (unknown), Erica Pranzini, Alice Santi, Leonardo Brunetti, Luca Piemontese, Paolo Tortorella, (unknown), (unknown), (unknown), (unknown), Ashok Pattnaik, Venkatesan Jayaprakash, Paolo Paoli, Antonio Lavecchia, Fulvio Loiodice	5
11	In Silico Identification of Novel Inhibitors Targeting the Homodimeric Interface of Superoxide Dismutase from the Dental Pathogen Streptococcus mutans 2022 ·Antioxidants ·Carmen Cerchia, Emanuela Roscetto, Rosarita Nasso, Maria Rosaria Catania, Emmanuele De Vendittis, Antonio Lavecchia, Mariorosario Masullo, Rosario Rullo	6
12	A chemoinformatics search for peroxisome proliferator-activated receptors ligands revealed a new pan-agonist able to reduce lipid accumulation and improve insulin sensitivity 2022 ·European Journal of Medicinal Chemistry ·(unknown), Carmen Cerchia, Antonio Laghezza, Luca Piemontese, Leonardo Brunetti, (unknown), Federica Gilardi, Aurélien Thomas, (unknown), Alice Santi, Paolo Tortorella, Paolo Paoli, Antonio Lavecchia, Fulvio Loiodice	7
13	Activation of Non-Canonical Autophagic Pathway through Inhibition of Non-Integrin Laminin Receptor in Neuronal Cells 2022 ·Cells ·(unknown), Iolanda Veneruso, Antonella Izzo, Maurizio Renna, (unknown), (unknown), Gaetano Calı̀, Sergio De Nicola, Patrizia Riccio, Valeria D’Argenio, Antonio Lavecchia, Daniela Sarnataro	6
14	Antagonizing S1P3 Receptor with Cell-Penetrating Pepducins in Skeletal Muscle Fibrosis 2021 ·International Journal of Molecular Sciences ·Angela Corvino, Ida Cerqua, (unknown), Giuseppe Caliendo, Ferdinando Fiorino, Francesco Frecentese, Elisa Magli, Elena Morelli, Elisa Perissutti, Vincenzo Santagada, Giuseppe Cirino, (unknown), Fiorentina Roviezzo, (unknown), Caterina Bernacchioni, Antonio Lavecchia, Chiara Donati, Beatrice Severino	2
15	Thiazolidinedione “Magic Bullets” Simultaneously Targeting PPARγ and HDACs: Design, Synthesis, and Investigations of their In Vitro and In Vivo Antitumor Effects 2021 ·Journal of Medicinal Chemistry ·Kalpana Tilekar, (unknown), Neha Upadhyay, (unknown), (unknown), Antonio Laghezza, Fulvio Loiodice, Franz‐Josef Meyer‐Almes, Renato J. Aguilera, Antonio Lavecchia, C. S. Ramaa	29
16	Inhibition of 37/67kDa Laminin-1 Receptor Restores APP Maturation and Reduces Amyloid-β in Human Skin Fibroblasts from Familial Alzheimer’s Disease 2020 ·Journal of Personalized Medicine ·(unknown), Antonella Izzo, Nunzia Mollo, Filomena Napolitano, (unknown), Francesca Margheri, Alessandra Mocali, Giuseppina Minopoli, (unknown), Federica Di Maggio, Valeria D’Argenio, Nunzia Montuori, Antonio Lavecchia, Daniela Sarnataro	11
17	Sulfonimide and Amide Derivatives as Novel PPARα Antagonists: Synthesis, Antiproliferative Activity, and Docking Studies 2020 ·ACS Medicinal Chemistry Letters ·Alessandra Ammazzalorso, Isabella Bruno, Rosalba Florio, Laura De Lellis, Antonio Laghezza, Carmen Cerchia, Barbara De Filippis, Marialuigia Fantacuzzi, Letizia Giampietro, Cristina Maccallini, Paolo Tortorella, Serena Veschi, Fulvio Loiodice, Antonio Lavecchia, Alessandro Cama, Rosa Amoroso	16
18	Development of Novel Amides as Noncovalent Inhibitors of Immunoproteasomes 2019 ·ChemMedChem ·Roberta Ettari, Carmen Cerchia, (unknown), (unknown), Ettore Novellino, Alessandra Bitto, Silvana Grasso, Antonio Lavecchia, Maria Zappalà	19
19	Identification of the First PPARα/γ Dual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation 2018 ·Journal of Medicinal Chemistry ·Antonio Laghezza, Luca Piemontese, Carmen Cerchia, Roberta Montanari, Davide Capelli, Marco Giudici, Maurizio Crestani, Paolo Tortorella, Franck Peiretti, G. Pochetti, Antonio Lavecchia, Fulvio Loiodice	33
20	Characterizing the 1,4-Dihydropyridines Binding Interactions in the L-Type Ca ²⁺ Channel: Model Construction and Docking Calculations 2007 ·Journal of Medicinal Chemistry ·Sandro Cosconati, Luciana Marinelli, Antonio Lavecchia, Ettore Novellino	85

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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