Alison D. O’Brien

22.3k total citations · 5 hit papers
201 papers, 17.3k citations indexed

About

Alison D. O’Brien is a scholar working on Endocrinology, Infectious Diseases and Molecular Biology. According to data from OpenAlex, Alison D. O’Brien has authored 201 papers receiving a total of 17.3k indexed citations (citations by other indexed papers that have themselves been cited), including 134 papers in Endocrinology, 125 papers in Infectious Diseases and 38 papers in Molecular Biology. Recurrent topics in Alison D. O’Brien's work include Escherichia coli research studies (132 papers), Viral gastroenteritis research and epidemiology (110 papers) and Clostridium difficile and Clostridium perfringens research (43 papers). Alison D. O’Brien is often cited by papers focused on Escherichia coli research studies (132 papers), Viral gastroenteritis research and epidemiology (110 papers) and Clostridium difficile and Clostridium perfringens research (43 papers). Alison D. O’Brien collaborates with scholars based in United States, United Kingdom and Germany. Alison D. O’Brien's co-authors include R K Holmes, Angela R. Melton‐Celsa, Randall K. Holmes, John W. Newland, Samuel B. Formal, Vernon L. Tesh, Marian L. McKee, Gerald D. LaVeck, James B. Kaper and James E. Samuel and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Alison D. O’Brien

200 papers receiving 16.4k citations

Hit Papers

Multicenter Evaluation of a... 1984 2026 1998 2012 2012 1987 1984 1986 1985 200 400 600
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Multicenter Evaluation of a Sequence-Based Protocol for Subtyping Shiga Toxins and Standardizing Stx Nomenclature
    2012 626 citations Louise D. Teel, Nancy Strockbine et al. profile →
  2. Shiga and Shiga-like toxins
    1987 556 citations Alison D. O’Brien et al. profile →
  3. Shiga-Like Toxin-Converting Phages from Escherichia coli Strains That Cause Hemorrhagic Colitis or Infantile Diarrhea
    1984 495 citations Alison D. O’Brien et al. profile →
  4. Two toxin-converting phages from Escherichia coli O157:H7 strain 933 encode antigenically distinct toxins with similar biologic activities
    1986 469 citations Alison D. O’Brien et al. Infection and Immunity profile →
  5. The Diarrheal Response of Humans to Some Classic Serotypes of Enteropathogenic Escherichia coli is Dependent on a Plasmid Encoding an Enteroadhesiveness Factor
    1985 402 citations James B. Kaper, Alison D. O’Brien et al. The Journal of Infectious Diseases profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Alison D. O’Brien United States 73 12.1k 9.6k 3.2k 2.9k 2.8k 201 17.3k
Michael S. Donnenberg United States 56 10.6k 0.9× 5.9k 0.6× 3.4k 1.1× 3.5k 1.2× 637 0.2× 130 13.8k
Chihiro Sasakawa Japan 78 6.9k 0.6× 4.2k 0.4× 1.9k 0.6× 7.2k 2.5× 4.4k 1.6× 233 18.9k
Stephen B. Calderwood United States 66 6.4k 0.5× 4.0k 0.4× 2.0k 0.6× 3.8k 1.3× 2.7k 1.0× 235 15.9k
Michael Hensel Germany 61 5.4k 0.4× 2.5k 0.3× 5.7k 1.8× 3.8k 1.3× 1.6k 0.6× 223 13.1k
Renée M. Tsolis United States 71 4.9k 0.4× 3.9k 0.4× 6.9k 2.2× 6.5k 2.3× 2.9k 1.0× 173 17.0k
Roy M. Robins‐Browne Australia 68 5.3k 0.4× 5.7k 0.6× 2.5k 0.8× 3.0k 1.0× 1.2k 0.4× 289 13.8k
Vanessa Sperandio United States 55 6.2k 0.5× 3.7k 0.4× 3.0k 0.9× 7.5k 2.6× 771 0.3× 138 13.9k
Denise M. Monack United States 71 4.0k 0.3× 3.5k 0.4× 3.9k 1.2× 12.8k 4.5× 7.7k 2.8× 134 22.1k
John D. Clements United States 67 3.1k 0.3× 3.6k 0.4× 1.1k 0.3× 5.7k 2.0× 3.1k 1.1× 209 15.7k
Pierre Gounon France 68 3.0k 0.2× 2.5k 0.3× 1.3k 0.4× 6.5k 2.3× 1.3k 0.5× 158 14.4k

Countries citing papers authored by Alison D. O’Brien

Since Specialization
Citations

This map shows the geographic impact of Alison D. O’Brien's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alison D. O’Brien with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alison D. O’Brien more than expected).

Fields of papers citing papers by Alison D. O’Brien

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alison D. O’Brien. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alison D. O’Brien. The network helps show where Alison D. O’Brien may publish in the future.

Co-authorship network of co-authors of Alison D. O’Brien

This figure shows the co-authorship network connecting the top 25 collaborators of Alison D. O’Brien. A scholar is included among the top collaborators of Alison D. O’Brien based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alison D. O’Brien. Alison D. O’Brien is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
2.
Eeuwen, Trevor van, Hua Jiang, Alison D. O’Brien, et al.. (2025). Rapid DNA cleavage by the LINE-1 endonuclease proximal to DNA ends and at mismatches. Journal of Biological Chemistry. 302(1). 110994–110994. 1 indexed citations
3.
Lindsey, Rebecca L., et al.. (2020). The Virulence of Escherichia coli O157:H7 Isolates in Mice Depends on Shiga Toxin Type 2a (Stx2a)-Induction and High Levels of Stx2a in Stool. Frontiers in Cellular and Infection Microbiology. 10. 62–62. 15 indexed citations
4.
Abdeltawab, Nourtan F., et al.. (2015). Mapping of genetic loci that modulate differential colonization by Escherichia coli O157:H7 TUV86-2 in advanced recombinant inbred BXD mice. BMC Genomics. 16(1). 947–947. 3 indexed citations
5.
Boisen, Nadia, Anne‐Marie Hansen, Angela R. Melton‐Celsa, et al.. (2014). The Presence of the pAA Plasmid in the German O104:H4 Shiga Toxin Type 2a (Stx2a)–Producing Enteroaggregative Escherichia coli Strain Promotes the Translocation of Stx2a Across an Epithelial Cell Monolayer. The Journal of Infectious Diseases. 210(12). 1909–1919. 31 indexed citations
6.
Mohawk, Krystle L., Angela R. Melton‐Celsa, Cory M. Robinson, & Alison D. O’Brien. (2010). Neutralizing antibodies to Shiga toxin type 2 (Stx2) reduce colonization of mice by Stx2-expressing Escherichia coli O157:H7. Vaccine. 28(30). 4777–4785. 34 indexed citations
7.
Robinson, Cory M., James F. Sinclair, Michael J. Smith, & Alison D. O’Brien. (2006). Shiga toxin of enterohemorrhagic Escherichia coli type O157:H7 promotes intestinal colonization. Proceedings of the National Academy of Sciences. 103(25). 9667–9672. 136 indexed citations
8.
Smith, Michael J., Louise D. Teel, Hernandes F. Carvalho, Angela R. Melton‐Celsa, & Alison D. O’Brien. (2006). Development of a hybrid Shiga holotoxoid vaccine to elicit heterologous protection against Shiga toxins types 1 and 2☆. Vaccine. 24(19). 4122–4129. 48 indexed citations
9.
Karpman, Diana, Zivile Békássy, Mohamed A. Karmali, et al.. (2002). Antibodies to intimin and Escherichia coli secreted proteins A and B in patients with enterohemorrhagic Escherichia coli infections. Pediatric Nephrology. 17(3). 201–211. 31 indexed citations
10.
Gewirtz, Andrew T., Peter O. Simon, Clare K. Schmitt, et al.. (2001). Salmonella typhimurium translocates flagellin across intestinal epithelia, inducing a proinflammatory response. Journal of Clinical Investigation. 107(1). 99–109. 317 indexed citations
11.
12.
Kaper, James B. & Alison D. O’Brien. (1998). Escherichia coli 0157:H7 and other shiga toxin-producing E. coli strains. ASM Press eBooks. 96 indexed citations
13.
Oswald, Éric, P. Pohl, E. Jacquemin, et al.. (1994). Specific DNA probes to detect Escherichia coli strains producing cytotoxic necrotising factor type 1 or type 2. Journal of Medical Microbiology. 40(6). 428–434. 33 indexed citations
14.
Donnenberg, Michael S., Saul Tzipori, Marian L. McKee, et al.. (1993). The role of the eae gene of enterohemorrhagic Escherichia coli in intimate attachment in vitro and in a porcine model.. Journal of Clinical Investigation. 92(3). 1418–1424. 280 indexed citations
15.
16.
Moore, Marjorie A., et al.. (1988). Production of a Shiga-like cytotoxin by Campylobacter. Microbial Pathogenesis. 4(6). 455–462. 23 indexed citations
17.
Karch, Helge, Nancy Strockbine, & Alison D. O’Brien. (1986). Growth ofEscherichia coliin the presence of trimethoprim-sulfamethoxazole facilitates detection of Shiga-like toxin producing strains by colony blot assay. FEMS Microbiology Letters. 35(2-3). 141–145. 81 indexed citations
18.
O’Brien, Alison D., et al.. (1985). Additional evidence that the Lps gene locus regulates natural resistance to S. typhimurium in mice.. The Journal of Immunology. 134(5). 2820–2823. 25 indexed citations
19.
Lissner, C R, R. N. Swanson, & Alison D. O’Brien. (1983). Genetic control of the innate resistance of mice to Salmonella typhimurium: expression of the Ity gene in peritoneal and splenic macrophages isolated in vitro.. The Journal of Immunology. 131(6). 3006–3013. 217 indexed citations
20.
O’Brien, Alison D., et al.. (1978). Invasive Escherichia coli. Journal of the American Veterinary Medical Association. 173(5). 596–598. 10 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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