Alessandra Castegna

10.8k total citations · 4 hit papers
62 papers, 8.6k citations indexed

About

Alessandra Castegna is a scholar working on Molecular Biology, Physiology and Immunology. According to data from OpenAlex, Alessandra Castegna has authored 62 papers receiving a total of 8.6k indexed citations (citations by other indexed papers that have themselves been cited), including 44 papers in Molecular Biology, 16 papers in Physiology and 16 papers in Immunology. Recurrent topics in Alessandra Castegna's work include Mitochondrial Function and Pathology (21 papers), Immune cells in cancer (13 papers) and Alzheimer's disease research and treatments (12 papers). Alessandra Castegna is often cited by papers focused on Mitochondrial Function and Pathology (21 papers), Immune cells in cancer (13 papers) and Alzheimer's disease research and treatments (12 papers). Alessandra Castegna collaborates with scholars based in Italy, United States and Belgium. Alessandra Castegna's co-authors include D. Allan Butterfield, Antonella Viola, Jennifer Drake, Ricardo Sánchez‐Rodríguez, Chava B. Pocernich, Fabio Munari, Tommaso Scolaro, Jon B. Klein, Visith Thongboonkerd and William R. Markesbery and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and PLoS ONE.

In The Last Decade

Alessandra Castegna

62 papers receiving 8.4k citations

Hit Papers

The Metabolic Signature o... 2001 2026 2009 2017 2019 2001 2002 2021 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. The Metabolic Signature of Macrophage Responses
    2019 1.4k citations Antonella Viola, Fabio Munari et al. Frontiers in Immunology profile →
  2. Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid β-peptide
    2001 961 citations D. Allan Butterfield, Alessandra Castegna et al. profile →
  3. Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer’s disease brain contribute to neuronal death1
    2002 581 citations Alessandra Castegna, Christopher M. Lauderback et al. profile →
  4. Reactive Oxygen Species in Macrophages: Sources and Targets
    2021 276 citations Marcella Canton, Ricardo Sánchez‐Rodríguez et al. Frontiers in Immunology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Alessandra Castegna Italy 38 4.5k 2.9k 1.5k 780 731 62 8.6k
Takuji Shirasawa Japan 59 5.4k 1.2× 2.8k 1.0× 1.1k 0.7× 382 0.5× 574 0.8× 209 10.4k
Byung Pal Yu United States 47 3.3k 0.7× 2.5k 0.9× 807 0.5× 536 0.7× 570 0.8× 161 8.0k
Anu Kauppinen Finland 51 4.6k 1.0× 2.2k 0.8× 1.5k 1.0× 1.1k 1.3× 722 1.0× 125 9.9k
Wolfgang F. Graier Austria 54 5.2k 1.2× 2.8k 1.0× 754 0.5× 263 0.3× 578 0.8× 241 9.5k
Simonetta Camandola United States 43 3.5k 0.8× 2.3k 0.8× 963 0.6× 1.3k 1.6× 913 1.2× 77 8.1k
Basilia Zingarelli United States 58 4.1k 0.9× 2.4k 0.8× 2.6k 1.7× 426 0.5× 1.2k 1.6× 212 11.2k
Zezong Gu United States 33 3.3k 0.7× 1.8k 0.6× 545 0.4× 870 1.1× 705 1.0× 75 6.3k
Hartmut Kleinert Germany 42 2.9k 0.6× 3.2k 1.1× 1.4k 0.9× 365 0.5× 837 1.1× 98 8.1k
Ana I. Rojo Spain 44 6.3k 1.4× 1.2k 0.4× 713 0.5× 1.2k 1.5× 526 0.7× 75 9.5k
Anne Nègre‐Salvayre France 63 4.9k 1.1× 2.1k 0.7× 2.0k 1.3× 195 0.3× 1.1k 1.4× 181 11.8k

Countries citing papers authored by Alessandra Castegna

Since Specialization
Citations

This map shows the geographic impact of Alessandra Castegna's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alessandra Castegna with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alessandra Castegna more than expected).

Fields of papers citing papers by Alessandra Castegna

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alessandra Castegna. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alessandra Castegna. The network helps show where Alessandra Castegna may publish in the future.

Co-authorship network of co-authors of Alessandra Castegna

This figure shows the co-authorship network connecting the top 25 collaborators of Alessandra Castegna. A scholar is included among the top collaborators of Alessandra Castegna based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alessandra Castegna. Alessandra Castegna is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Arduino, Ilaria, et al.. (2024). Microfluidic development of brain-derived neurotrophic factor loaded solid lipid nanoparticles: An in vitro evaluation in the post-traumatic brain injury neuroinflammation model. Journal of Drug Delivery Science and Technology. 96. 105699–105699. 9 indexed citations
2.
Moriggi, Manuela, Lucia Ruggiero, Enrica Torretta, et al.. (2024). Muscle Proteome Analysis of Facioscapulohumeral Dystrophy Patients Reveals a Metabolic Rewiring Promoting Oxidative/Reductive Stress Contributing to the Loss of Muscle Function. Antioxidants. 13(11). 1406–1406. 3 indexed citations
3.
Masgras, Ionica, Giuseppe Cannino, Francesco Ciscato, et al.. (2022). Tumor growth of neurofibromin-deficient cells is driven by decreased respiration and hampered by NAD+ and SIRT3. Cell Death and Differentiation. 29(10). 1996–2008. 15 indexed citations
4.
Serra, Marina, Mario Di Matteo, Jens Serneels, et al.. (2022). Deletion of Lactate Dehydrogenase-A Impairs Oncogene-Induced Mouse Hepatocellular Carcinoma Development. Cellular and Molecular Gastroenterology and Hepatology. 14(3). 609–624. 18 indexed citations
5.
Spera, Iolanda, Ricardo Sánchez‐Rodríguez, Maria Favia, et al.. (2021). The J2-Immortalized Murine Macrophage Cell Line Displays Phenotypical and Metabolic Features of Primary BMDMs in Their M1 and M2 Polarization State. Cancers. 13(21). 5478–5478. 9 indexed citations
6.
Munari, Fabio, Denis Vecellio Reane, Alessandra Castegna, et al.. (2021). The dominant-negative mitochondrial calcium uniporter subunit MCUb drives macrophage polarization during skeletal muscle regeneration. Science Signaling. 14(707). eabf3838–eabf3838. 24 indexed citations
7.
Favia, Maria, Antonella Muscella, Alessandra Castegna, et al.. (2020). Differential Expression of ADP/ATP Carriers as a Biomarker of Metabolic Remodeling and Survival in Kidney Cancers. Biomolecules. 11(1). 38–38. 19 indexed citations
8.
Sánchez‐Rodríguez, Ricardo, Fabio Munari, Roberta Angioni, et al.. (2020). Targeting monoamine oxidase to dampen NLRP3 inflammasome activation in inflammation. Cellular and Molecular Immunology. 18(5). 1311–1313. 40 indexed citations
9.
Menga, Alessio, Marina Serra, Simona Todisco, et al.. (2020). Glufosinate constrains synchronous and metachronous metastasis by promoting anti‐tumor macrophages. EMBO Molecular Medicine. 12(10). e11210–e11210. 51 indexed citations
10.
Castegna, Alessandra, Alessio Menga, Monica Montopoli, et al.. (2020). Pharmacological targets of metabolism in disease: Opportunities from macrophages. Pharmacology & Therapeutics. 210. 107521–107521. 51 indexed citations
11.
Viola, Antonella, Fabio Munari, Ricardo Sánchez‐Rodríguez, Tommaso Scolaro, & Alessandra Castegna. (2019). The Metabolic Signature of Macrophage Responses. Frontiers in Immunology. 10. 1462–1462. 1396 indexed citations breakdown →
12.
Spera, Iolanda, Roberta Menabò, Erika M. Palmieri, et al.. (2018). Monoamine oxidase-dependent histamine catabolism accounts for post-ischemic cardiac redox imbalance and injury. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864(9). 3050–3059. 19 indexed citations
13.
Butterfield, D. Allan, Erika M. Palmieri, & Alessandra Castegna. (2016). Clinical implications from proteomic studies in neurodegenerative diseases: lessons from mitochondrial proteins. Expert Review of Proteomics. 13(3). 259–274. 24 indexed citations
14.
Palmieri, Erika M., Alessio Menga, D. Craig Hooper, et al.. (2016). Blockade of Glutamine Synthetase Enhances Inflammatory Response in Microglial Cells. Antioxidants and Redox Signaling. 26(8). 351–363. 62 indexed citations
15.
Todisco, Simona, Maria Antonietta Di Noia, Alessandra Castegna, et al.. (2013). The Saccharomyces cerevisiae gene YPR011c encodes a mitochondrial transporter of adenosine 5′-phosphosulfate and 3′-phospho-adenosine 5′-phosphosulfate. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1837(2). 326–334. 20 indexed citations
16.
Castegna, Alessandra, Pasquale Scarcia, Gennaro Agrimi, et al.. (2010). Identification and Functional Characterization of a Novel Mitochondrial Carrier for Citrate and Oxoglutarate in Saccharomyces cerevisiae. Journal of Biological Chemistry. 285(23). 17359–17370. 108 indexed citations
17.
Castegna, Alessandra, Christopher M. Lauderback, Hafiz Mohmmad‐Abdul, & D. Allan Butterfield. (2004). Modulation of phospholipid asymmetry in synaptosomal membranes by the lipid peroxidation products, 4-hydroxynonenal and acrolein: implications for Alzheimer's disease. Brain Research. 1004(1-2). 193–197. 81 indexed citations
18.
Castegna, Alessandra, Visith Thongboonkerd, Jon B. Klein, et al.. (2003). Proteomic identification of nitrated proteins in Alzheimer's disease brain. Journal of Neurochemistry. 85(6). 1394–1401. 456 indexed citations
19.
Castegna, Alessandra, Michael Y. Aksenov, Visith Thongboonkerd, et al.. (2002). Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase‐related protein 2, α‐enolase and heat shock cognate 71. Journal of Neurochemistry. 82(6). 1524–1532. 497 indexed citations
20.
Castegna, Alessandra, Michael Y. Aksenov, Marina Aksenova, et al.. (2002). Proteomic identification of oxidatively modified proteins in alzheimer’s disease brain. part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1. Free Radical Biology and Medicine. 33(4). 562–571. 484 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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