Alessandra Castegna

10.8k citations

62 papers · 8.6k indexed · 4 hit papers · h-index 38

Biological Psychiatry top 1%
Physiology top 0.5%
- Alzheimer's disease research and treatments 12
Neurology top 1%
- Neuroinflammation and Neurodegeneration Mechanisms 5
Clinical Biochemistry top 0.5%
- Metabolism and Genetic Disorders 7
Biochemistry top 0.5%
Molecular Biology
- Mitochondrial Function and Pathology 21
- Epigenetics and DNA Methylation 8
- S100 Proteins and Annexins 4
Immunology
- Immune cells in cancer 13
Cancer Research
- Cancer, Hypoxia, and Metabolism 7

Co-authors: D. Allan Butterfield Antonella Viola Jennifer Drake Ricardo Sánchez‐Rodríguez Chava B. Pocernich Fabio Munari Tommaso Scolaro Jon B. Klein
Cited by: Biological Psychiatry Physiology Neurology
Partner nations: Italy United States Belgium

In The Last Decade

Alessandra Castegna

62 papers receiving 8.4k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2021 Reactive Oxygen Species in Macrophages: Sources and Targets
2019 The Metabolic Signature of Macrophage Responses
2002 Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer’s disease brain contribute to neuronal death1
2001 Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid β-peptide

Peers

Countries citing papers authored by Alessandra Castegna

Since Specialization

Citations

This map shows the geographic impact of Alessandra Castegna's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alessandra Castegna with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alessandra Castegna more than expected).

Fields of papers citing papers by Alessandra Castegna

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alessandra Castegna. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alessandra Castegna. The network helps show where Alessandra Castegna may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Alessandra Castegna, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Alessandra Castegna Line = papers co-authored together Alessandra Castegna links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Muscle Proteome Analysis of Facioscapulohumeral Dystrophy Patients Reveals a Metabolic Rewiring Promoting Oxidative/Reductive Stress Contributing to the Loss of Muscle Function Manuela Moriggi,Lucia Ruggiero,Enrica Torretta,Dario Zoppi,Beatrice Arosio,Evelyn Ferri,Alessandra Castegna,Chiara Fiorillo,Cecilia Gelfi,Daniele Capitanio	2024	3
2	Microfluidic development of brain-derived neurotrophic factor loaded solid lipid nanoparticles: An in vitro evaluation in the post-traumatic brain injury neuroinflammation model Federica Sommonte,Ilaria Arduino,Rosa Maria Iacobazzi,Luna Laera,Teresa Silvestri,Angela Lopedota,Alessandra Castegna,Nunzio Denora	2024	9
3	Tumor growth of neurofibromin-deficient cells is driven by decreased respiration and hampered by NAD+ and SIRT3 Ionica Masgras,Giuseppe Cannino,Francesco Ciscato,Carlos Sànchez‐Martìn,Fereshteh Babaei Darvishi,Francesca Scantamburlo,Marco Pizzi,Alessio Menga,Dolores Fregona,Alessandra Castegna,Andrea Rasola	2022	15
4	Deletion of Lactate Dehydrogenase-A Impairs Oncogene-Induced Mouse Hepatocellular Carcinoma Development Marina Serra,Mario Di Matteo,Jens Serneels,Rajesh Pal,Sarah Trusso Cafarello,Martina Lanza,Carlos Sànchez‐Martìn,Matthias Evert,Alessandra Castegna,Diego F. Calvisi,Massimiliano Mazzone,Amedeo Columbano	2022	18
5	The J2-Immortalized Murine Macrophage Cell Line Displays Phenotypical and Metabolic Features of Primary BMDMs in Their M1 and M2 Polarization State Iolanda Spera,Ricardo Sánchez‐Rodríguez,Maria Favia,Alessio Menga,Francisca C. Venegas,Roberta Angioni,Fabio Munari,Martina Lanza,Annalisa Campanella,Ciro Leonardo Pierri,Marcella Canton,Alessandra Castegna	2021	9
6	The dominant-negative mitochondrial calcium uniporter subunit MCUb drives macrophage polarization during skeletal muscle regeneration Simona Feno,Fabio Munari,Denis Vecellio Reane,Rosanna Gissi,Dieu-Huong Hoang,Alessandra Castegna,Bénédicte Chazaud,Antonella Viola,Rosario Rizzuto,Anna Raffaello	2021	24
7	Differential Expression of ADP/ATP Carriers as a Biomarker of Metabolic Remodeling and Survival in Kidney Cancers Lucia Trisolini,Luna Laera,Maria Favia,Antonella Muscella,Alessandra Castegna,Vito Pesce,Lorenzo Guerra,Anna Grassi,Mariateresa Volpicella,Ciro Leonardo Pierri	2020	19
8	Pharmacological targets of metabolism in disease: Opportunities from macrophages Alessandra Castegna,Rosanna Gissi,Alessio Menga,Monica Montopoli,Maria Favia,Antonella Viola,Marcella Canton	2020	51
9	Targeting monoamine oxidase to dampen NLRP3 inflammasome activation in inflammation Ricardo Sánchez‐Rodríguez,Fabio Munari,Roberta Angioni,Francisca C. Venegas,Andrielly H.R. Agnellini,María Paulette Castro‐Gil,Alessandra Castegna,Roberto Luisetto,Antonella Viola,Marcella Canton	2020	40
10	The Metabolic Signature of Macrophage Responsesbreakdown → Antonella Viola,Fabio Munari,Ricardo Sánchez‐Rodríguez,Tommaso Scolaro,Alessandra Castegna	2019	1396
11	Monoamine oxidase-dependent histamine catabolism accounts for post-ischemic cardiac redox imbalance and injury Veronica Costiniti,Iolanda Spera,Roberta Menabò,Erika M. Palmieri,Alessio Menga,Pasquale Scarcia,Vito Porcelli,Rosanna Gissi,Alessandra Castegna,Marcella Canton	2018	19
12	Blockade of Glutamine Synthetase Enhances Inflammatory Response in Microglial Cells Erika M. Palmieri,Alessio Menga,Aurore Lebrun,D. Craig Hooper,D. Allan Butterfield,Massimiliano Mazzone,Alessandra Castegna	2016	62
13	Clinical implications from proteomic studies in neurodegenerative diseases: lessons from mitochondrial proteins D. Allan Butterfield,Erika M. Palmieri,Alessandra Castegna	2016	24
14	Glutamine synthetase desensitizes differentiated adipocytes to proinflammatory stimuli by raising intracellular glutamine levels Erika M. Palmieri,Iolanda Spera,Alessio Menga,Vittoria Infantino,Vito Iacobazzi,Alessandra Castegna	2014	31
15	Identification and Functional Characterization of a Novel Mitochondrial Carrier for Citrate and Oxoglutarate in Saccharomyces cerevisiae Alessandra Castegna,Pasquale Scarcia,Gennaro Agrimi,Luigi Palmieri,Hanspeter Rottensteiner,Iolanda Spera,Lucrezia Germinario,Ferdinando Palmieri	2010	108
16	Identification of mitochondrial carriers in Saccharomyces cerevisiae by transport assay of reconstituted recombinant proteins Ferdinando Palmieri,Gennaro Agrimi,Emanuela Blanco,Alessandra Castegna,Maria Antonietta Di Noia,Vito Iacobazzi,Francesco M. Lasorsa,C Marobbio,Luigi Palmieri,Pasquale Scarcia,Simona Todisco,Angelo Vozza,John E. Walker	2006	140
17	Modulation of phospholipid asymmetry in synaptosomal membranes by the lipid peroxidation products, 4-hydroxynonenal and acrolein: implications for Alzheimer's disease Alessandra Castegna,Christopher M. Lauderback,Hafiz Mohmmad‐Abdul,D. Allan Butterfield	2004	81
18	Quantitative proteomics analysis of specific protein expression and oxidative modification in aged senescence-accelerated-prone 8 mice brain H. Fai Poon,Alessandra Castegna,Susan A. Farr,Visith Thongboonkerd,Bert C. Lynn,William A. Banks,John E. Morley,Jon B. Klein,D. Allan Butterfield	2004	122
19	Proteomic analysis of brain proteins in the gracile axonal dystrophy (gad) mouse, a syndrome that emanates from dysfunctional ubiquitin carboxyl‐terminal hydrolase L‐1, reveals oxidation of key proteins Alessandra Castegna,Visith Thongboonkerd,Jon B. Klein,Bert C. Lynn,Yulai Wang,Hitoshi Osaka,Keiji Wada,D. Allan Butterfield	2004	67
20	Proteomic identification of nitrated proteins in Alzheimer's disease brain Alessandra Castegna,Visith Thongboonkerd,Jon B. Klein,Bert C. Lynn,William R. Markesbery,D. Allan Butterfield	2003	456

About Alessandra Castegna

Alessandra Castegna is a scholar working on Biological Psychiatry, Clinical Biochemistry and Neurology, having authored 62 papers that have together received 8.6k indexed citations. Recurring topics across this work include Mitochondrial Function and Pathology (21 papers), Immune cells in cancer (13 papers), Alzheimer's disease research and treatments (12 papers), Epigenetics and DNA Methylation (8 papers), Metabolism and Genetic Disorders (7 papers), Cancer, Hypoxia, and Metabolism (7 papers), Neuroinflammation and Neurodegeneration Mechanisms (5 papers) and S100 Proteins and Annexins (4 papers). The work is most often cited by research in Biological Psychiatry (396 citations), Physiology (2.9k citations) and Neurology (780 citations). Alessandra Castegna has collaborated with scholars based in Italy, United States and Belgium. Frequent co-authors include D. Allan Butterfield, Antonella Viola, Jennifer Drake, Ricardo Sánchez‐Rodríguez, Chava B. Pocernich, Fabio Munari, Tommaso Scolaro, Jon B. Klein, Visith Thongboonkerd and William R. Markesbery.

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