Alain Sewer

7.4k citations

57 papers · 6.2k · 2 hit papers · h-index 29

Impact in

Cancer Research top 0.5%
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
Molecular Biology top 2%
- Circular RNAs in diseases
- RNA Interference and Gene Delivery
- RNA modifications and cancer
- RNA Research and Splicing
- Extracellular vesicles in disease

Papers in

Cancer Research 15
- MicroRNA in disease regulation 10
- Carcinogens and Genotoxicity Assessment 4
Health, Toxicology and Mutagenesis 15
- Air Quality and Health Impacts 11
- Indoor Air Quality and Microbial Exposure 5

Co-authors: Manuel C. Peitsch (41 shared papers)Julia Hoeng (41 shared papers)Mihaela Zavolan (4 shared papers)Florian Pierre Martin (32 shared papers)Thomas Tuschl (2 shared papers)Sébastien Pfeffer (2 shared papers)Glenn C. Randall (1 shared paper)Mariana Lagos‐Quintana (1 shared paper)
Journals: Food and Chemical Toxicology (6 papers)Toxicology Letters (4 papers)Chemical Research in Toxicology (2 papers)BMC Bioinformatics (2 papers)Drug Discovery Today (2 papers)
Partner nations: Switzerland Germany United States

In The Last Decade

Alain Sewer

56 papers receiving 6.0k citations

Alain Sewer's Hit Papers

align trajectories log scale

A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing 2007 · 3.1k citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

2007 Cell
2005 Nature Methods

Peers

Countries citing papers authored by Alain Sewer

Since Specialization

Citations

This map shows the geographic impact of Alain Sewer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alain Sewer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alain Sewer more than expected).

Fields of papers citing papers by Alain Sewer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alain Sewer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alain Sewer. The network helps show where Alain Sewer may publish in the future.

Co-authors

The 25 scholars most cited alongside Alain Sewer, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Alain Sewer Line = papers co-authored together Alain Sewer links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 57 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing Cell ·Pablo Landgraf, Mirabela Rusu, Robert P. Sheridan, Alain Sewer, Nicola Iovino, Alexei A. Aravin, Sébastien Pfeffer, Amanda Rice Hit paper breakdown →	2007	3135
2	Identification of microRNAs of the herpesvirus family Nature Methods ·Sébastien Pfeffer, Alain Sewer, Mariana Lagos‐Quintana, Robert P. Sheridan, Chris Sander, Friedrich A. Grässer, Linda Faye van Dyk, Caleb H. Ho Hit paper breakdown →	2005	944
3	Identification of clustered microRNAs using an ab initio prediction method BMC Bioinformatics ·Alain Sewer, Nicodème Paul, Pablo Landgraf, Alexei A. Aravin, Sébastien Pfeffer, Michael Brownstein, Thomas Tuschl, Erik van Nimwegen	2005	204
4	Effects of Dicer and Argonaute down-regulation on mRNA levels in human HEK293 cells Nucleic Acids Research ·Daniela Schmitter, Jody N. Filkowski, Alain Sewer, Ramesh S. Pillai, Edward J. Oakeley, Mihaela Zavolan, Petr Svoboda, Witold Filipowicz	2006	166
5	Human bronchial epithelial cells exposed in vitro to cigarette smoke at the air-liquid interface resemble bronchial epithelium from human smokers American Journal of Physiology-Lung Cellular and Molecular Physiology ·Carole Mathis, Carine Poussin, Dirk Weisensee, Stephan Gebel, Arnd Hengstermann, Alain Sewer, Vincenzo Belcastro, Yang Xiang	2013	136
6	Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models BMC Bioinformatics ·Florian Pierre Martin, Alain Sewer, Marja Talikka, Yang Xiang, Julia Hoeng, Manuel C. Peitsch	2014	94
7	Causal biological network database: a comprehensive platform of causal biological network models focused on the pulmonary and vascular systems Database ·Stéphanie Boué, Marja Talikka, Jurjen W. Westra, William Hayes, Anselmo Di Fabio, Jennifer M. Park, Walter K. Schlage, Alain Sewer	2015	94
8	Assessment of network perturbation amplitudes by applying high-throughput data to causal biological networks BMC Systems Biology ·Florian Pierre Martin, Ty M. Thomson, Alain Sewer, David A. Drubin, Carole Mathis, Dirk Weisensee, Dexter R. Pratt, Julia Hoeng	2012	86
9	A network-based approach to quantifying the impact of biologically active substances Drug Discovery Today ·Julia Hoeng, Renée Deehan, Dexter R. Pratt, Florian Pierre Martin, Alain Sewer, Ty M. Thomson, David A. Drubin, Christina A. Waters	2011	85
10	Marek's Disease Virus Type 2 (MDV-2)-Encoded MicroRNAs Show No Sequence Conservation with Those Encoded by MDV-1 Journal of Virology ·Yongxiu Yao, Yuguang Zhao, Hongtao Xu, Lorraine P. Smith, Charles Henderson Lawrie, Alain Sewer, Mihaela Zavolan, Venugopal Nair	2007	82
11	A framework for in vitro systems toxicology assessment of e-liquids Toxicology Mechanisms and Methods ·Anita R. Iskandar, Ignacio González-Suárez, Shoaib Majeed, Diego Marescotti, Alain Sewer, Yang Xiang, Patrice Leroy, Emmanuel Guedj	2016	73
12	Alterations in the sputum proteome and transcriptome in smokers and early-stage COPD subjects Journal of Proteomics ·Bjoern Titz, Alain Sewer, Thomas Schneider, Ashraf Elamin, Florian Pierre Martin, Sophie Dijon, Karsta Luettich, Emmanuel Guedj	2015	71
13	Case study: the role of mechanistic network models in systems toxicology Drug Discovery Today ·Julia Hoeng, Marja Talikka, Florian Pierre Martin, Alain Sewer, Anita R. Iskandar, Walter K. Schlage, Manuel C. Peitsch +1 other	2013	62
14	Quantitative assessment of biological impact using transcriptomic data and mechanistic network models Toxicology and Applied Pharmacology ·Ty M. Thomson, Alain Sewer, Florian Pierre Martin, Vincenzo Belcastro, Brian P. Frushour, Stephan Gebel, Jennifer M. Park, Walter K. Schlage	2013	55
15	In vitro systems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue cultures Toxicology Mechanisms and Methods ·Walter K. Schlage, Anita R. Iskandar, Radina M. Kostadinova, Yang Xiang, Alain Sewer, Shoaib Majeed, Diana Kuehn, Stefan Frentzel	2014	54
16	A systems toxicology approach for comparative assessment: Biological impact of an aerosol from a candidate modified-risk tobacco product and cigarette smoke on human organotypic bronchial epithelial cultures Toxicology in Vitro ·Anita R. Iskandar, Carole Mathis, Walter K. Schlage, Stefan Frentzel, Patrice Leroy, Yang Xiang, Alain Sewer, Shoaib Majeed	2016	54
17	Systems Toxicology Assessment of the Biological Impact of a Candidate Modified Risk Tobacco Product on Human Organotypic Oral Epithelial Cultures Chemical Research in Toxicology ·Filippo Zanetti, Alain Sewer, Carole Mathis, Anita R. Iskandar, Radina M. Kostadinova, Walter K. Schlage, Patrice Leroy, Shoaib Majeed	2016	52
18	Assessment of mitochondrial function following short- and long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product and reference cigarettes Food and Chemical Toxicology ·Dominika Malińska, Jędrzej Szymański, Paulina Patalas‐Krawczyk, Bernadeta Michalska, Aleksandra Wojtala, Monika Prill, Małgorzata Partyka, Karolina Drabik	2018	50
19	Comparative systems toxicology analysis of cigarette smoke and aerosol from a candidate modified risk tobacco product in organotypic human gingival epithelial cultures: A 3-day repeated exposure study Food and Chemical Toxicology ·Filippo Zanetti, Bjoern Titz, Alain Sewer, Giuseppe Lo Sasso, Elena Scotti, Walter K. Schlage, Carole Mathis, Patrice Leroy	2016	47
20	The Response of Human Nasal and Bronchial Organotypic Tissue Cultures to Repeated Whole Cigarette Smoke Exposure International Journal of Toxicology ·Marja Talikka, Radina M. Kostadinova, Yang Xiang, Carole Mathis, Alain Sewer, Shoaib Majeed, Diana Kuehn, Stefan Frentzel	2014	43

About Alain Sewer

Alain Sewer is a scholar working on Cancer Research, Health, Toxicology and Mutagenesis, Molecular Biology, Periodontics and Pulmonary and Respiratory Medicine, having authored 57 papers that have together received 6.2k indexed citations. Recurring topics across this work include Air Quality and Health Impacts (11 papers), MicroRNA in disease regulation (10 papers), Molecular Biology Techniques and Applications (8 papers), Computational Drug Discovery Methods (6 papers), Gene Regulatory Network Analysis (6 papers), Bioinformatics and Genomic Networks (5 papers), Indoor Air Quality and Microbial Exposure (5 papers) and Carcinogens and Genotoxicity Assessment (4 papers). The work is most often cited by research in Cancer Research (3.4k citations), Molecular Biology (3.8k citations), Health, Toxicology and Mutagenesis (494 citations), Immunology (451 citations) and Physiology (535 citations). Alain Sewer has collaborated with scholars based in Switzerland, Germany and United States. Frequent co-authors include Manuel C. Peitsch, Julia Hoeng, Mihaela Zavolan, Florian Pierre Martin, Thomas Tuschl, Sébastien Pfeffer, Glenn C. Randall, Mariana Lagos‐Quintana, Jingyue Ju and Minchen Chien. Their work appears in journals such as Food and Chemical Toxicology, Toxicology Letters, Chemical Research in Toxicology, BMC Bioinformatics and Drug Discovery Today.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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