Akiko Itai

6.3k total citations
173 papers, 4.9k citations indexed

About

Akiko Itai is a scholar working on Molecular Biology, Organic Chemistry and Cancer Research. According to data from OpenAlex, Akiko Itai has authored 173 papers receiving a total of 4.9k indexed citations (citations by other indexed papers that have themselves been cited), including 90 papers in Molecular Biology, 58 papers in Organic Chemistry and 30 papers in Cancer Research. Recurrent topics in Akiko Itai's work include NF-κB Signaling Pathways (24 papers), Computational Drug Discovery Methods (14 papers) and Natural product bioactivities and synthesis (14 papers). Akiko Itai is often cited by papers focused on NF-κB Signaling Pathways (24 papers), Computational Drug Discovery Methods (14 papers) and Natural product bioactivities and synthesis (14 papers). Akiko Itai collaborates with scholars based in Japan, United States and United Kingdom. Akiko Itai's co-authors include Yöichi Iitaka, Koichi Shudo, Nobuo Tomioka, Susumu Muto, Yasuyuki Endo, Hiroyuki Kagechika, Yoshiharu Toriumi, Kazunori Odashima, Shoichi Saito and Miho Mizutani and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Journal of Biological Chemistry.

In The Last Decade

Akiko Itai

170 papers receiving 4.7k citations

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author						Papers	Cites
Akiko Itai	2.3k	1.6k	749	469	448	173	4.9k
Kevin T. Chapman	3.5k 1.5×	2.8k 1.7×	371 0.5×	703 1.5×	403 0.9×	82	6.1k
Hitoshi Hori	1.9k 0.9×	632 0.4×	604 0.8×	362 0.8×	358 0.8×	218	4.6k
David L. Vander Jagt	3.6k 1.6×	686 0.4×	1.2k 1.6×	516 1.1×	369 0.8×	113	6.8k
Billy W. Day	3.5k 1.6×	2.4k 1.5×	669 0.9×	1.4k 2.9×	753 1.7×	178	7.5k
Malcolm F. G. Stevens	4.1k 1.8×	4.1k 2.5×	559 0.7×	849 1.8×	353 0.8×	203	8.7k
Michael Gütschow	3.3k 1.5×	2.2k 1.3×	468 0.6×	941 2.0×	891 2.0×	281	6.4k
Shuichi Hirono	2.7k 1.2×	951 0.6×	179 0.2×	577 1.2×	446 1.0×	178	5.6k
Michael D. Threadgill	1.6k 0.7×	1.1k 0.7×	481 0.6×	688 1.5×	249 0.6×	167	3.8k
Hongbin Sun	3.6k 1.6×	1.8k 1.1×	356 0.5×	863 1.8×	511 1.1×	210	7.4k
Francesco Leonetti	1.7k 0.8×	1.6k 1.0×	402 0.5×	708 1.5×	992 2.2×	93	4.3k

Countries citing papers authored by Akiko Itai

Since Specialization

Citations

This map shows the geographic impact of Akiko Itai's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Akiko Itai with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Akiko Itai more than expected).

Fields of papers citing papers by Akiko Itai

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Akiko Itai. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Akiko Itai. The network helps show where Akiko Itai may publish in the future.

Co-authorship network of co-authors of Akiko Itai

This figure shows the co-authorship network connecting the top 25 collaborators of Akiko Itai. A scholar is included among the top collaborators of Akiko Itai based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Akiko Itai. Akiko Itai is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Fukao, Keita, Takafumi Ohara, Noriyuki Naya, et al.. (2023). Design, Synthesis, and Anti-Inflammatory Evaluation of a Novel PPARδ Agonist with a 4-(1-Pyrrolidinyl)piperidine Structure. Journal of Medicinal Chemistry. 66(16). 11428–11446. 7 indexed citations

Liu, Yujing, Nobuyoshi Kitaichi, Di Wu, et al.. (2020). Attenuation of experimental autoimmune uveoretinitis in mice by IKKβ inhibitor IMD-0354. Biochemical and Biophysical Research Communications. 525(3). 589–594. 5 indexed citations

Suzuki, Jun‐ichi, et al.. (2018). A novel IkB kinase inhibitor attenuates ligature‐induced periodontal disease in mice. Journal of Periodontal Research. 54(2). 164–173. 10 indexed citations

Toda, Aska, Kenjiro Sawada, Koji Nakamura, et al.. (2016). Targeting Inhibitor of κB Kinase β Prevents Inflammation-Induced Preterm Delivery by Inhibiting IL-6 Production from Amniotic Cells. American Journal Of Pathology. 186(3). 616–629. 13 indexed citations

Kinose, Yasuto, Kenjiro Sawada, Hiroshi Makino, et al.. (2015). IKKβ Regulates VEGF Expression and Is a Potential Therapeutic Target for Ovarian Cancer as an Antiangiogenic Treatment. Molecular Cancer Therapeutics. 14(4). 909–919. 23 indexed citations

Dewan, Md. Zahidunnabi, Yasunori Saitoh, Susumu Muto, et al.. (2011). An IκB kinase 2 inhibitor IMD‐0354 suppresses the survival of adult T‐cell leukemia cells. Cancer Science. 103(1). 100–106. 27 indexed citations

Matsuda, Akihisa, Akane Tanaka, Susumu Muto, et al.. (2010). A novel NF-κB inhibitor improves glucocorticoid sensitivity of canine neoplastic lymphoid cells by up-regulating expression of glucocorticoid receptors. Research in Veterinary Science. 89(3). 378–382. 17 indexed citations

Ogawa, Hirohisa, Masahiko Azuma, Susumu Muto, et al.. (2008). Antiallergic and Anti-Inflammatory Effects of a Novel IκB Kinase β Inhibitor, IMD-0354, in a Mouse Model of Allergic Inflammation. International Archives of Allergy and Immunology. 148(3). 186–198. 53 indexed citations

Tanaka, Akane, Susumu Muto, Kyungsook Jung, Akiko Itai, & Hiroshi Matsuda. (2006). Topical Application with a New NF-κB Inhibitor Improves Atopic Dermatitis in NC/NgaTnd Mice. Journal of Investigative Dermatology. 127(4). 855–863. 83 indexed citations

10.

Mizutani, Miho, et al.. (2006). Effective handling of induced‐fit motion in flexible docking. Proteins Structure Function and Bioinformatics. 63(4). 878–891. 53 indexed citations

11.

Onai, Yasuyuki, Jun‐ichi Suzuki, Yasuhiro Maejima, et al.. (2006). Inhibition of NF-κB improves left ventricular remodeling and cardiac dysfunction after myocardial infarction. American Journal of Physiology-Heart and Circulatory Physiology. 292(1). H530–H538. 98 indexed citations

12.

Sato, Hiromi, Seiichi Ishida, Kyoko Toda, et al.. (2005). New Approaches to Mechanism Analysis for Drug Discovery Using DNA Microarray Data Combined with KeyMolnet. Current Drug Discovery Technologies. 2(2). 89–98. 42 indexed citations

13.

Kamon, Junji, Toshimasa Yamauchi, Susumu Muto, et al.. (2004). A novel IKKβ inhibitor stimulates adiponectin levels and ameliorates obesity-linked insulin resistance. Biochemical and Biophysical Research Communications. 323(1). 242–248. 61 indexed citations

14.

Endo, Yasuyuki, Toru Iijima, Yuko Yamakoshi, et al.. (2001). Potent estrogen agonists based on carborane as a hydrophobic skeletal structure. Chemistry & Biology. 8(4). 341–355. 159 indexed citations

15.

Iijima, Toru, Emiko Kawachi, Noriko Inoue, et al.. (2001). Structure–activity study of retinoid agonists bearing substituted dicarba-closo-dodecaborane. Relation between retinoidal activity and conformation of two aromatic nuclei. Bioorganic & Medicinal Chemistry Letters. 11(10). 1307–1311. 37 indexed citations

16.

Kawachi, Emiko, et al.. (1998). Novel Thiazolidinedione Derivatives with Retinoid Synergistic Activity.. Biological and Pharmaceutical Bulletin. 21(5). 547–549. 11 indexed citations

17.

Brobey, Reynolds, et al.. (1997). Lead Discovery of Inhibitors of the Dihydrofolate Reductase Domain ofPlasmodium falciparumDihydrofolate Reductase-Thymidylate Synthase. Biochemical and Biophysical Research Communications. 235(3). 515–519. 62 indexed citations

18.

Azumaya, Isao, Kazuya Yamaguchi, Hiroyuki Kagechika, et al.. (1994). Stereochemistry of Benzanilides and N-Methylbenzanilides. YAKUGAKU ZASSHI. 114(6). 414–430. 26 indexed citations

19.

Itai, Akiko & Nobuo Tomioka. (1987). Present stage of computer-assisted molecular design.. Journal of Synthetic Organic Chemistry Japan. 45(11). 1119–1128.

20.

Sügimura, Takashi, Takashi Kawachi, Minako Nagao, et al.. (1977). Mutagenic Principle(s) in Tryptophan and Phenylalanine Pyrolysis Products. Proceedings of the Japan Academy. 53(1). 58–61. 226 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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