A. Wittinghofer

2.3k total citations · 1 hit paper
24 papers, 1.9k citations indexed

About

A. Wittinghofer is a scholar working on Molecular Biology, Materials Chemistry and Oncology. According to data from OpenAlex, A. Wittinghofer has authored 24 papers receiving a total of 1.9k indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Molecular Biology, 7 papers in Materials Chemistry and 6 papers in Oncology. Recurrent topics in A. Wittinghofer's work include Protein Kinase Regulation and GTPase Signaling (8 papers), Enzyme Structure and Function (7 papers) and Cancer-related Molecular Pathways (5 papers). A. Wittinghofer is often cited by papers focused on Protein Kinase Regulation and GTPase Signaling (8 papers), Enzyme Structure and Function (7 papers) and Cancer-related Molecular Pathways (5 papers). A. Wittinghofer collaborates with scholars based in Germany, France and United States. A. Wittinghofer's co-authors include Roger S. Goody, E.F. Pai, Ute Krengel, Wolfgang Kabsch, Gregory A. Petsko, Hans Robert Kalbitzer, Matthias Frech, Ilme Schlichting, Matthias Geyer and Benjamin Bader and has published in prestigious journals such as Nature, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

A. Wittinghofer

24 papers receiving 1.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis.

1990 939 citations E.F. Pai, Ute Krengel et al. The EMBO Journal profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
A. Wittinghofer Germany	18	1.7k	474	393	215	151	24	1.9k
Jarmila Jancarik United States	11	1.7k 1.0×	412 0.9×	437 1.1×	487 2.3×	97 0.6×	13	2.1k
Tai-he Xia Sweden	5	1.5k 0.9×	319 0.7×	219 0.6×	134 0.6×	127 0.8×	6	1.8k
Susan S. Taylor United States	15	1.2k 0.7×	255 0.5×	225 0.6×	120 0.6×	180 1.2×	16	1.5k
Fernando Marchiori Italy	25	1.6k 0.9×	231 0.5×	256 0.7×	153 0.7×	86 0.6×	89	1.9k
J.-P. Mornon France	20	1.3k 0.8×	309 0.7×	265 0.7×	182 0.8×	52 0.3×	54	2.1k
Y. Muto Japan	26	2.1k 1.2×	204 0.4×	150 0.4×	178 0.8×	109 0.7×	92	2.3k
Roger D. Wade United States	15	1.0k 0.6×	215 0.5×	223 0.6×	136 0.6×	155 1.0×	20	1.7k
Ishwar Radhakrishnan United States	30	3.0k 1.8×	360 0.8×	227 0.6×	274 1.3×	127 0.8×	65	3.4k
Hong Lin United States	23	2.2k 1.3×	338 0.7×	221 0.6×	366 1.7×	71 0.5×	50	2.6k
Y. Devedjiev United States	20	849 0.5×	273 0.6×	405 1.0×	73 0.3×	110 0.7×	29	1.3k

Countries citing papers authored by A. Wittinghofer

Since Specialization

Citations

This map shows the geographic impact of A. Wittinghofer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by A. Wittinghofer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites A. Wittinghofer more than expected).

Fields of papers citing papers by A. Wittinghofer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by A. Wittinghofer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by A. Wittinghofer. The network helps show where A. Wittinghofer may publish in the future.

Co-authorship network of co-authors of A. Wittinghofer

This figure shows the co-authorship network connecting the top 25 collaborators of A. Wittinghofer. A scholar is included among the top collaborators of A. Wittinghofer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with A. Wittinghofer. A. Wittinghofer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Bader, Benjamin, Karsten Kuhn, David J. Owen, et al.. (2000). Bioorganic synthesis of lipid-modified proteins for the study of signal transduction. Nature. 403(6766). 223–226. 138 indexed citations

Vetter, Ingrid R., Thomas Linnemann, Sabine Wohlgemuth, et al.. (1999). Structural and biochemical analysis of Ras‐effector signaling via RalGDS. FEBS Letters. 451(2). 175–180. 85 indexed citations

Schweins, Thomas, Matthias Geyer, Hans Robert Kalbitzer, A. Wittinghofer, & A. Warshel. (1996). Linear Free Energy Relationships in the Intrinsic and GTPase Activating Protein-Stimulated Guanosine 5‘-Triphosphate Hydrolysis of p21^ras. Biochemistry. 35(45). 14225–14231. 64 indexed citations

Frech, Matthias, Tom Darden, Lee G. Pedersen, et al.. (1994). Role of Glutamine-61 in the Hydrolysis of GTP by p21H-ras: An Experimental and Theoretical Study. Biochemistry. 33(11). 3237–3244. 112 indexed citations

Wittinghofer, A.. (1994). The structure of transducin Gαt: More to view than just Ras. Cell. 76(2). 201–204. 18 indexed citations

Gulbins, E., K. Mark Coggeshall, Christelle Langlet, et al.. (1994). Activation of Ras in vitro and in intact fibroblasts by the Vav guanine nucleotide exchange protein.. Molecular and Cellular Biology. 14(2). 906–913. 73 indexed citations

Wittinghofer, A.. (1993). From EF-Tu to P21ras and back again. Current Biology. 3(12). 874–876. 2 indexed citations

Borasio, Gian Domenico, Annette Markus, A. Wittinghofer, Yves‐Alain Barde, & Rolf Heumann. (1993). Involvement of ras p21 in neurotrophin-induced response of sensory, but not sympathetic neurons.. The Journal of Cell Biology. 121(3). 665–672. 99 indexed citations

Foley, C. K., Lee G. Pedersen, Paul S. Charifson, et al.. (1992). Simulation of the solution structure of the H-ras p21-GTP complex. Biochemistry. 31(21). 4951–4959. 38 indexed citations

10.

Hahnel, Christian, Kurt Gottmann, A. Wittinghofer, & H. D. Lux. (1992). P21^ras Oncogene Protein Selectively Increases Low‐voltage‐activated Ca²⁺ Current Density in Embryonic Chick Dorsal Root Ganglion Neurons. European Journal of Neuroscience. 4(4). 361–368. 17 indexed citations

11.

Serth, Jürgen, Wolfgang Weber, Matthias Frech, A. Wittinghofer, & Alfred Pingoud. (1992). Binding of the h-ras p21 GTPase activating protein by the activated epidermal growth factor receptor leads to inhibition of the p21 GTPase activity in vitro. Biochemistry. 31(28). 6361–6365. 23 indexed citations

12.

Kalbitzer, Hans Robert, et al.. (1991). C-terminal structure and mobility of rabbit skeletal muscle light meromyosin as studied by one- and two-dimensional proton NMR spectroscopy and x-ray small-angle scattering. Biochemistry. 30(32). 8083–8091. 9 indexed citations

13.

Maéda, Kayo, et al.. (1991). Rabbit skeletal muscle myosin unfolded carboxyl‐terminus and its role in molecular assembly. FEBS Letters. 281(1-2). 23–26. 23 indexed citations

14.

Hescheler, J., Franz‐Josef Klinz, G. Schultz, & A. Wittinghofer. (1991). Ras proteins activate calcium channels in neuronal cells. Cellular Signalling. 3(2). 127–133. 11 indexed citations

15.

Pai, E.F., Ute Krengel, Gregory A. Petsko, et al.. (1990). Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis.. The EMBO Journal. 9(8). 2351–2359. 939 indexed citations breakdown →

16.

Frech, Matthias, Ilme Schlichting, A. Wittinghofer, & Pierre Teilhard de Chardin. (1990). Guanine nucleotide binding properties of the mammalian RalA protein produced in Escherichia coli.. Journal of Biological Chemistry. 265(11). 6353–6359. 48 indexed citations

17.

Scherer, Anna, Jacob John, Roger S. Goody, et al.. (1989). Crystallization and preliminary X-ray analysis of the human c-H-ras-oncogene product p21 complexed with GTP analogues. Journal of Molecular Biology. 206(1). 257–259. 41 indexed citations

18.

Schlichting, Ilme, A. Wittinghofer, & Paul Rösch. (1988). Proton NMR studies of the GDP.Mg2+ complex of the Ha-ras oncogene product p21. Biochemical and Biophysical Research Communications. 150(1). 444–448. 14 indexed citations

19.

Wittinghofer, A., et al.. (1977). Structural requirements of the GDP binding site of elongation factor Tu. FEBS Letters. 75(1-2). 241–243. 15 indexed citations

20.

Gast, W., R. Leberman, Georg E. Schulz, & A. Wittinghofer. (1976). Crystals of partially trypsin-digested elongation factor Tu. Journal of Molecular Biology. 106(4). 943–950. 34 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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