Standout Papers

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptoti... 1996 2026 2006 2016 6.1k
  1. Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade (1997)
    Peng Li, Deepak Nijhawan et al. Cell
  2. Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c (1996)
    Xuesong Liu, Jie Yang et al. Cell
  3. Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked (1997)
    Jie Yang, Xuesong Liu et al. Science
  4. Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors (1998)
    Xu Luo, I. Imawati Budihardjo et al. Cell
  5. Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition (2000)
    Chunying Du, Min Fang et al. Cell
  6. Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3 (1997)
    Hua Zou, William J. Henzel et al. Cell
  7. Biochemical Pathways of Caspase Activation During Apoptosis (1999)
    I. Imawati Budihardjo, George R. Oliver et al. Annual Review of Cell and Developmental Biology
  8. Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase (2012)
    Liming Sun, Huayi Wang et al. Cell
  9. Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α (2009)
    Sudan He, Lai Wang et al. Cell
  10. An APAF-1·Cytochrome c Multimeric Complex Is a Functional Apoptosome That Activates Procaspase-9 (1999)
    Hua Zou, Yuchen Li et al. Journal of Biological Chemistry
  11. DFF, a Heterodimeric Protein That Functions Downstream of Caspase-3 to Trigger DNA Fragmentation during Apoptosis (1997)
    Xuesong Liu, Hua Zou et al. Cell
  12. Endonuclease G is an apoptotic DNase when released from mitochondria (2001)
    Xu Luo, Xiaodong Wang et al. Nature
  13. Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3 (2014)
    Huayi Wang, Liming Sun et al. Molecular Cell
  14. Cytochrome C -Mediated Apoptosis (2004)
    Xuejun Jiang, Xiaodong Wang Annual Review of Biochemistry
  15. TNF-α Induces Two Distinct Caspase-8 Activation Pathways (2008)
    Lai Wang, Fenghe Du et al. Cell
  16. Structural parts involved in activation and inactivation of the sodium channel (1989)
    Walter Stühmer, Franco Conti et al. Nature
  17. SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis (1994)
    Xiaodong Wang, Ryuichiro Sato et al. Cell
  18. SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene (1993)
    Chieko Yokoyama, Xiaodong Wang et al. Cell
  19. The Mitochondrial Phosphatase PGAM5 Functions at the Convergence Point of Multiple Necrotic Death Pathways (2012)
    Zhigao Wang, Hui Jiang et al. Cell
  20. Mule/ARF-BP1, a BH3-Only E3 Ubiquitin Ligase, Catalyzes the Polyubiquitination of Mcl-1 and Regulates Apoptosis (2005)
    Qing Zhong, Wenhua Gao et al. Cell
  21. Structural basis of IAP recognition by Smac/DIABLO (2000)
    Geng Wu, Jijie Chai et al. Nature
  22. Structural and biochemical basis of apoptotic activation by Smac/DIABLO (2000)
    Jijie Chai, Chunying Du et al. Nature
  23. Three-Dimensional Structure of the Apoptosome (2002)
    Devrim Acehan, Xuejun Jiang et al. Molecular Cell
  24. Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3–mediated pathway (2011)
    Sudan He, Yuqiong Liang et al. Proceedings of the National Academy of Sciences
  25. Argonaute2 Cleaves the Anti-Guide Strand of siRNA during RISC Activation (2005)
    Tim Rand, Sean Petersen et al. Cell
  26. R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway (2003)
    Qinghua Liu, Tim Rand et al. Science
  27. A Small Molecule Smac Mimic Potentiates TRAIL- and TNFα-Mediated Cell Death (2004)
    Li Lin, Jef K. De Brabander et al. Science
  28. SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element. (1993)
    Xianxin Hua, Chieko Yokoyama et al. Proceedings of the National Academy of Sciences
  29. Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK (2011)
    Zhi‐Gang She, Fenghe Du et al. Proceedings of the National Academy of Sciences
  30. Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1 (2020)
    Bo Yan, Youwei Ai et al. Molecular Cell
  31. Identification of a prefrontal cortex-to-amygdala pathway for chronic stress-induced anxiety (2020)
    Wei-Zhu Liu, Wenhua Zhang et al. Nature Communications
  32. The biochemical pathways of apoptotic, necroptotic, pyroptotic, and ferroptotic cell death (2024)
    Youwei Ai, Yutong Meng et al. Molecular Cell

Immediate Impact

19 by Nobel laureates 124 from Science/Nature 300 standout
Sub-graph 1 of 14

Citing Papers

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
2016 StandoutNature
Pore-forming activity and structural autoinhibition of the gasdermin family
2016 StandoutNature
84 intermediate papers

Works of Xiaodong Wang being referenced

Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3
2014 Standout
Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
2009 Standout
and 24 more

Author Peers

Author Last Decade Papers Cites
Xiaodong Wang 48200 7966 11272 8395 305 62.6k
Guy S. Salvesen 36881 8899 9492 5895 293 54.0k
Junying Yuan 35952 5046 10246 10840 251 51.9k
Peter Vandenabeele 36202 7287 20547 9166 449 60.6k
Stanley J. Korsmeyer 59060 15203 15078 7918 230 83.2k
Josef Penninger 40322 14525 17755 5038 578 76.7k
Paul Tempst 61550 8205 8945 4843 320 79.9k
Andreas Strasser 36764 12965 18604 5903 476 57.4k
Hediye Erdjument‐Bromage 52815 7276 6857 4678 283 67.2k
John Blenis 38903 8109 6419 3615 221 51.3k
Jiahuai Han 29478 5771 10897 4114 319 43.3k

All Works

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