Standout Papers

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy... 2001 2026 2009 2017 4.6k
  1. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy (2005)
    Hannah Farmer, Nuala McCabe et al. Nature
  2. The DNA-damage response in human biology and disease (2009)
    Stephen P. Jackson, Jiří Bártek Nature
  3. A DNA damage checkpoint response in telomere-initiated senescence (2003)
    Fabrizio d’Adda di Fagagna, Philip M. Reaper et al. Nature
  4. DNA double-strand breaks: signaling, repair and the cancer connection (2001)
    Kum Kum Khanna, Stephen P. Jackson Nature Genetics
  5. ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response (2017)
    Andrew N. Blackford, Stephen P. Jackson Molecular Cell
  6. Human CtIP promotes DNA end resection (2007)
    Alessandro A. Sartori, Claudia Lukas et al. Nature
  7. The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen (1993)
    Tanya Gottlieb, Stephen P. Jackson Cell
  8. Identification and Characterization of a Novel and Specific Inhibitor of the Ataxia-Telangiectasia Mutated Kinase ATM (2004)
    Ian Hickson, Yan Zhao et al. Cancer Research
  9. Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage (2005)
    Jacob Falck, Julia Coates et al. Nature
  10. Sensing and repairing DNA double-strand breaks (2002)
    Stephen P. Jackson Carcinogenesis
  11. Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications (2011)
    Sophie E. Polo, Stephen P. Jackson Genes & Development
  12. MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks (2005)
    Manuel Stucki, Julie A. Clapperton et al. Cell
  13. ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks (2005)
    Ali Jazayeri, Jacob Falck et al. Nature Cell Biology
  14. Regulation of p53 in response to DNA damage (1999)
    Nicholas D. Lakin, Stephen P. Jackson Oncogene
  15. O-glycosylation of eukaryotic transcription factors: Implications for mechanisms of transcriptional regulation (1988)
    Stephen P. Jackson, Robert Tjian Cell
  16. The DNA-dependent protein kinase (1999)
    Graeme C.M. Smith, Stephen P. Jackson Genes & Development
  17. Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation (1995)
    T Blunt, Guillermo E. Taccioli et al. Cell
  18. Orchestration of the DNA-Damage Response by the RNF8 Ubiquitin Ligase (2007)
    Nadine K. Kolas, J. Ross Chapman et al. Science
  19. A Pathway of Double-Strand Break Rejoining Dependent upon ATM, Artemis, and Proteins Locating to γ-H2AX Foci (2004)
    Enriqueta Riballo, Martin Kühne et al. Molecular Cell
  20. The MRE11 complex: at the crossroads of DNA repair and checkpoint signalling (2002)
    Damien D’Amours, Stephen P. Jackson Nature Reviews Molecular Cell Biology
  21. DNA-dependent protein kinase catalytic subunit: A relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product (1995)
    Katharine O. Hartley, David A. Gell et al. Cell
  22. Deubiquitylating enzymes and drug discovery: emerging opportunities (2017)
    Jeanine A. Harrigan, Xavier Jacq et al. Nature Reviews Drug Discovery
  23. GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase (1990)
    Stephen P. Jackson, Susan P. Lees‐Miller et al. Cell
  24. Small-molecule–induced DNA damage identifies alternative DNA structures in human genes (2012)
    Raphaël Rodriguez, Kyle M. Miller et al. Nature Chemical Biology
  25. XLF Interacts with the XRCC4-DNA Ligase IV Complex to Promote DNA Nonhomologous End-Joining (2006)
    Stephen P. Jackson et al. Cell
  26. Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination (1994)
    Guillermo E. Taccioli, Tanya Gottlieb et al. Science
  27. Interfaces Between the Detection, Signaling, and Repair of DNA Damage (2002)
    John Rouse, Stephen P. Jackson Science
  28. A role for Saccharomyces cerevisiae histone H2A in DNA repair (2000)
    Jessica A. Downs, Noel F. Lowndes et al. Nature
  29. Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining (2010)
    Kyle M. Miller, Jorrit Tjeertes et al. Nature Structural & Molecular Biology
  30. Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks (2014)
    François Aymard, Béatrix Bugler et al. Nature Structural & Molecular Biology
  31. Regulation of DNA Damage Responses by Ubiquitin and SUMO (2013)
    Stephen P. Jackson, Daniel Durocher Molecular Cell
  32. Targeting DNA Repair in Cancer: Beyond PARP Inhibitors (2016)
    Jessica Brown, Brent O’Carrigan et al. Cancer Discovery
  33. A Compendium of Mutational Signatures of Environmental Agents (2019)
    Jill E. Kucab, Xueqing Zou et al. Cell

Immediate Impact

22 by Nobel laureates 76 from Science/Nature 178 standout
Sub-graph 1 of 19

Citing Papers

A view on drug resistance in cancer
2019 StandoutNature
cGAS surveillance of micronuclei links genome instability to innate immunity
2017 StandoutNature
5 intermediate papers

Works of Stephen P. Jackson being referenced

A high-throughput in vivo micronucleus assay for genome instability screening in mice
2014
DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of Sir3p
1999
and 10 more

Author Peers

Author Last Decade Papers Cites
Stephen P. Jackson 55777 20612 7204 9693 346 65.3k
Jiří Bártek 40971 22942 4563 9316 378 52.8k
Charles J. Sherr 38985 30272 5932 6856 270 57.5k
David Beach 34200 20131 3497 5250 241 46.9k
J. Wade Harper 48175 19357 4964 7006 303 61.5k
Stephen J. Elledge 75009 27392 9992 13658 360 91.4k
Scott W. Lowe 49438 22670 4162 16688 324 68.3k
Paul Tempst 61550 8205 6470 7571 320 79.9k
Philip Leder 40876 11779 10441 5681 351 63.1k
Hediye Erdjument‐Bromage 52815 7276 5421 5909 283 67.2k
Jan H.J. Hoeijmakers 37648 7748 5683 8279 394 47.2k

All Works

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2026