Standout Papers

The pro- and anti-inflammatory properties of the cytokin... 2001 2026 2009 2017 2.4k
  1. The pro- and anti-inflammatory properties of the cytokine interleukin-6 (2011)
    Jürgen Scheller, Athena Chalaris et al. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  2. IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer (2009)
    Sergei I. Grivennikov, Eliad Karin et al. Cancer Cell
  3. IL-6 Trans-Signaling via the Soluble IL-6 Receptor: Importance for the Pro-Inflammatory Activities of IL-6 (2012)
    Stefan Rose‐John International Journal of Biological Sciences
  4. Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer (2011)
    Marina Lesina, Magdalena U. Kurkowski et al. Cancer Cell
  5. IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation (2001)
    Suzanne M. Hurst, Thomas S. Wilkinson et al. Immunity
  6. Soluble receptors for cytokines and growth factors: generation and biological function (1994)
    Stefan Rose‐John, Peter C. Heinrich Biochemical Journal
  7. IL-6 pathway in the liver: From physiopathology to therapy (2016)
    Dirk Schmidt‐Arras, Stefan Rose‐John Journal of Hepatology
  8. TGF-β Suppresses Tumor Progression in Colon Cancer by Inhibition of IL-6 trans-Signaling (2004)
    Christoph Becker, Massimo Claudio Fantini et al. Immunity
  9. The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion (2003)
    Christian Hundhausen, Theo A. Berkhout et al. Blood
  10. A Switch from White to Brown Fat Increases Energy Expenditure in Cancer-Associated Cachexia (2014)
    Michele Petruzzelli, Martina Schweiger et al. Cell Metabolism
  11. Interleukin-6 Family Cytokines (2017)
    Stefan Rose‐John Cold Spring Harbor Perspectives in Biology
  12. Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer (2006)
    Stefan Rose‐John, Jürgen Scheller et al. Journal of Leukocyte Biology
  13. Soluble gp130 is the natural inhibitor of soluble interleukin‐6 receptor transsignaling responses (2001)
    Thomas Jostock, Jürgen Müllberg et al. European Journal of Biochemistry
  14. Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling (2011)
    Simon A. Jones, Jürgen Scheller et al. Journal of Clinical Investigation
  15. Interleukin-6: designing specific therapeutics for a complex cytokine (2018)
    Christoph Garbers, Sylvia Heink et al. Nature Reviews Drug Discovery
  16. Interleukin-6 and its receptors: A highly regulated and dynamic system (2014)
    Janina Wolf, Stefan Rose‐John et al. Cytokine
  17. Repopulating Microglia Promote Brain Repair in an IL-6-Dependent Manner (2020)
    Emily F. Willis, Kelli P. A. MacDonald et al. Cell
  18. Targeting IL-6 trans-signalling: past, present and future prospects (2023)
    Stefan Rose‐John, Brendan J. Jenkins et al. Nature reviews. Immunology
  19. Interleukin-6: obstacles to targeting a complex cytokine in critical illness (2021)
    Oliver J. McElvaney, Gerard F. Curley et al. The Lancet Respiratory Medicine

Immediate Impact

11 by Nobel laureates 31 from Science/Nature 124 standout
Sub-graph 1 of 19

Citing Papers

Reframing Immune-Mediated Inflammatory Diseases through Signature Cytokine Hubs
2021 Standout
Effective treatment of severe COVID-19 patients with tocilizumab
2020 Standout

Works of Stefan Rose‐John being referenced

Interleukin-6 and its receptors: A highly regulated and dynamic system
2014 Standout
Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling
2011 Standout
and 1 more

Author Peers

Author Last Decade Papers Cites
Stefan Rose‐John 17357 18253 13501 563 47.2k
Robert M. Strieter 16972 23746 12590 505 56.2k
Kouji Matsushima 12827 25342 11715 556 48.5k
Steven L. Kunkel 9731 21415 9559 524 47.5k
Joost J. Oppenheim 11389 28632 15004 448 53.5k
Jo Van Damme 13567 16549 12546 540 41.1k
Marc Feldmann 7826 23651 11157 554 52.9k
John J. O’Shea 14988 30779 10988 321 48.8k
Paola Allavena 21665 32722 14347 289 55.6k
Tadamitsu Kishimoto 25455 33603 21971 633 76.3k
Josef Penninger 14525 17755 40322 578 76.7k

All Works

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Rankless by CCL
2026