Standout Papers

A microRNA polycistron as a potential human oncogene 1993 2026 2004 2015 2.8k
  1. A microRNA polycistron as a potential human oncogene (2005)
    Lin He, J. Michael Thomson et al. Nature
  2. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents (1993)
    Scott W. Lowe, H. Earl Ruley et al. Cell
  3. p53 is required for radiation-induced apoptosis in mouse thymocytes (1993)
    Scott W. Lowe, Earlene M. Schmitt et al. Nature
  4. A microRNA component of the p53 tumour suppressor network (2007)
    Lin He, Xingyue He et al. Nature
  5. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours (1996)
    Thomas G. Graeber, Tyler Jacks et al. Nature
  6. Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas (2007)
    Wen Xue, Lars Zender et al. Nature
  7. Apoptosis (2002)
    Ricky W. Johnstone, Astrid A. Ruefli et al. Cell
  8. Rb-Mediated Heterochromatin Formation and Silencing of E2F Target Genes during Cellular Senescence (2003)
    Masashi Narita, Édith Heard et al. Cell
  9. Apoptosis in cancer (2000)
    Scott W. Lowe, Athena W. Lin Carcinogenesis
  10. RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia (2011)
    Johannes Zuber, Junwei Shi et al. Nature
  11. Putting p53 in Context (2017)
    Edward R. Kastenhuber, Scott W. Lowe Cell
  12. p53 Status and the Efficacy of Cancer Therapy in Vivo (1994)
    Scott W. Lowe, Stephan Bodis et al. Science
  13. Control of apoptosis by p53 (2003)
    Jordan S. Fridman, Scott W. Lowe Oncogene
  14. Differential Requirement for Caspase 9 in Apoptotic Pathways In Vivo (1998)
    Razqallah Hakem, Anne Hakem et al. Cell
  15. Intrinsic tumour suppression (2004)
    Scott W. Lowe, Enriqué Cepero et al. Nature
  16. The microcosmos of cancer (2012)
    Amaia Lujambio, Scott W. Lowe Nature
  17. Identification and Validation of Oncogenes in Liver Cancer Using an Integrative Oncogenomic Approach (2006)
    Lars Zender, Mona S. Spector et al. Cell
  18. A Senescence Program Controlled by p53 and p16INK4a Contributes to the Outcome of Cancer Therapy (2002)
    Clemens A. Schmitt, Jordan S. Fridman et al. Cell
  19. Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy (2004)
    Hans-Guido Wendel, Elisa de Stanchina et al. Nature
  20. Inactivation of the apoptosis effector Apaf-1 in malignant melanoma (2001)
    Marı́a S. Soengas, Paola Capodieci et al. Nature
  21. FADD: Essential for Embryo Development and Signaling from Some, But Not All, Inducers of Apoptosis (1998)
    Wen‐Chen Yeh, José Luís de la Pompa et al. Science
  22. p53-Dependent apoptosis suppresses tumor growth and progression in vivo (1994)
    Holly Symonds, Leonard Krall et al. Cell
  23. Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling (1998)
    Athena W. Lin, Marta Barradas et al. Genes & Development
  24. Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes (1998)
    Minna Woo, Razqallah Hakem et al. Genes & Development
  25. Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity (2011)
    Yuchen Chien, Claudio Scuoppo et al. Genes & Development
  26. The gene encoding the splicing factor SF2/ASF is a proto-oncogene (2007)
    Rotem Karni, Elisa de Stanchina et al. Nature Structural & Molecular Biology
  27. Senolytic CAR T cells reverse senescence-associated pathologies (2020)
    Corina Amor, Judith Feucht et al. Nature
  28. Apoptosis and melanoma chemoresistance (2003)
    Marı́a S. Soengas, Scott W. Lowe Oncogene
  29. Non-Cell-Autonomous Tumor Suppression by p53 (2013)
    Amaia Lujambio, Leila Akkari et al. Cell
  30. Apaf-1 and Caspase-9 in p53-Dependent Apoptosis and Tumor Inhibition (1999)
    Marı́a S. Soengas, Rodolfo Alarcón et al. Science
  31. Tumor suppression by Ink4a–Arf: progress and puzzles (2003)
    Scott W. Lowe, Charles J. Sherr Current Opinion in Genetics & Development
  32. In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system (2014)
    Danilo Maddalo, Eusebio Manchado et al. Nature
  33. Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer (2015)
    Lukas E. Dow, Kevin P. O’Rourke et al. Cell
  34. Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor β Signaling (2014)
    Susann Weissmueller, Eusebio Manchado et al. Cell
  35. Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks (2020)
    William M. Schneider, Joseph M. Luna et al. Cell
  36. STING inhibits the reactivation of dormant metastasis in lung adenocarcinoma (2023)
    Jing Hu, Francisco J. Sánchez‐Rivera et al. Nature
  37. Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction (2024)
    Corina Amor, Yu-Jui Ho et al. Nature Aging
  38. Phenotypes and ontogeny of senescent hepatic stellate cells in metabolic dysfunction-associated steatohepatitis (2024)
    Chittampalli N. Yashaswini, Dipankar Bhattacharya et al. Journal of Hepatology

Immediate Impact

29 by Nobel laureates 56 from Science/Nature 184 standout
Sub-graph 1 of 13

Citing Papers

Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2021 Standout
5 intermediate papers

Works of Scott W. Lowe being referenced

Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors
2020 Nobel
Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer
2015 Standout
and 3 more

Author Peers

Author Last Decade Papers Cites
Scott W. Lowe 49438 22670 16688 324 68.3k
Ronald A. DePinho 55409 22760 13587 416 84.9k
Tyler Jacks 58358 33760 26145 336 86.1k
Carlos Cordon‐Cardo 40955 22560 12688 563 67.3k
Napoleone Ferrara 60705 20350 23583 257 97.7k
Charles J. Sherr 38985 30272 6856 270 57.5k
Curtis C. Harris 40543 21985 24469 571 65.7k
Sean J. Morrison 31942 21386 11402 181 61.2k
Pier Paolo Pandolfi 61139 12933 22576 449 79.2k
Stanley J. Korsmeyer 59060 15203 7600 230 83.2k
William G. Kaelin 35237 14721 22252 244 49.6k

All Works

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2026