Standout Papers

The Structure of the Potassium Channel: Molecular Basis of K <sup>+</sup> Conduction and Selec... 1998 2026 2007 2016 5.4k
  1. The Structure of the Potassium Channel: Molecular Basis of K + Conduction and Selectivity (1998)
    D. Doyle, João H. Morais‐Cabral et al. Science
  2. Crystal Structure of a Mammalian Voltage-Dependent Shaker Family K + Channel (2005)
    Stephen B. Long, Ernest B. Campbell et al. Science
  3. Chemistry of ion coordination and hydration revealed by a K+ channel–Fab complex at 2.0 Å resolution (2001)
    Yufeng Zhou, João H. Morais‐Cabral et al. Nature
  4. X-ray structure of a voltage-dependent K+ channel (2003)
    Youxing Jiang, Alice Lee et al. Nature
  5. X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity (2002)
    Raimund Dutzler, Ernest B. Campbell et al. Nature
  6. Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment (2007)
    Stephen B. Long, Xiao Tao et al. Nature
  7. Crystal structure and mechanism of a calcium-gated potassium channel (2002)
    Youxing Jiang, Alice Lee et al. Nature
  8. The open pore conformation of potassium channels (2002)
    Youxing Jiang, Alice Lee et al. Nature
  9. Crystal Structures of a Complexed and Peptide-Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ (1996)
    D. Doyle, Alice A. Lee et al. Cell
  10. Principles of Selective Ion Transport in Channels and Pumps (2005)
    Eric Gouaux, Roderick MacKinnon Science
  11. Voltage Sensor of Kv1.2: Structural Basis of Electromechanical Coupling (2005)
    Stephen B. Long, Ernest B. Campbell et al. Science
  12. Determination of the subunit stoichiometry of a voltage-activated potassium channel (1991)
    Roderick MacKinnon Nature
  13. Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failure. (1987)
    Judith K. Gwathmey, Roderick MacKinnon et al. Circulation Research
  14. Energetic optimization of ion conduction rate by the K+ selectivity filter (2001)
    João H. Morais‐Cabral, Yufeng Zhou et al. Nature
  15. Mutations in the K+ channel signature sequence (1994)
    Lise Heginbotham, Zheming Lu et al. Biophysical Journal
  16. Gating the Selectivity Filter in ClC Chloride Channels (2003)
    Raimund Dutzler, Ernest B. Campbell et al. Science
  17. The principle of gating charge movement in a voltage-dependent K+ channel (2003)
    Youxing Jiang, Vanessa Ruta et al. Nature
  18. Contribution of the S4 Segment to Gating Charge in the Shaker K+ Channel (1996)
    Sanjay Aggarwal, Roderick MacKinnon Neuron
  19. Mutations Affecting Internal TEA Blockade Identify the Probable Pore-Forming Region of a K + Channel (1991)
    Gary Yellen, Mark E. Jurman et al. Science
  20. Mutations Affecting Tea Blockade and Ion Permeation in Voltage-activated K + Channels (1990)
    Roderick MacKinnon, Gary Yellen Science
  21. The aromatic binding site for tetraethylammonium ion on potassium channels (1992)
    Lise Heginbotham, Roderick MacKinnon Neuron
  22. Revealing the Architecture of a K + Channel Pore Through Mutant Cycles with a Peptide Inhibitor (1995)
    Patricia Hidalgo, Roderick MacKinnon Science
  23. A Functional Connection Between the Pores of Distantly Related Ion Channels as Revealed by Mutant K + Channels (1992)
    Lise Heginbotham, Tatiana Abramson et al. Science
  24. Cryo-EM Structure of the Open Human Ether-à-go-go -Related K + Channel hERG (2017)
    Weiwei Wang, Roderick MacKinnon Cell
  25. Crystal Structure and Functional Analysis of the HERG Potassium Channel N Terminus (1998)
    João H. Morais‐Cabral, Alice A. Lee et al. Cell
  26. The Cavity and Pore Helices in the KcsA K + Channel: Electrostatic Stabilization of Monovalent Cations (1999)
    Benoı̂t Roux, Roderick MacKinnon Science
  27. Structural Conservation in Prokaryotic and Eukaryotic Potassium Channels (1998)
    Roderick MacKinnon, Steven L. Cohen et al. Science
  28. Potassium channels (2003)
    Roderick MacKinnon FEBS Letters
  29. Mechanism of charybdotoxin block of the high-conductance, Ca2+-activated K+ channel. (1988)
    Roderick MacKinnon, Christopher Miller The Journal of General Physiology
  30. Mutant Potassium Channels with Altered Binding of Charybdotoxin, a Pore-Blocking Peptide Inhibitor (1989)
    Roderick MacKinnon, Christopher Miller Science
  31. Force-induced conformational changes in PIEZO1 (2019)
    Yi‐Chih Lin, Yusong R. Guo et al. Nature

Immediate Impact

60 by Nobel laureates 119 from Science/Nature 136 standout
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Citing Papers

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153 intermediate papers

Works of Roderick MacKinnon being referenced

Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures
2018 Science
Chemistry of ion coordination and hydration revealed by a K+ channel–Fab complex at 2.0 Å resolution
2001 StandoutNature
and 83 more

Author Peers

Author Last Decade Papers Cites
Roderick MacKinnon 36284 16335 12955 166 42.2k
Erwin Neher 42526 33647 7623 254 56.4k
William A. Catterall 53944 37000 15198 483 69.3k
Michel Lazdunski 36810 16254 8876 570 48.1k
Thomas J. Jentsch 22933 10937 6852 225 28.3k
Brian T. Chait 36210 5579 3719 432 54.8k
Roger Y. Tsien 70492 28180 4337 315 110.3k
Fred J. Sigworth 19938 13405 6459 104 24.6k
David E. Clapham 32626 16806 6013 320 56.4k
Bertil Hille 18128 14367 3807 207 25.7k
Ernesto Carafoli 24057 7188 3250 489 32.8k

All Works

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