Standout Papers

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding P... 1983 2026 1997 2011 2.9k
  1. Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins (1989)
    Pamela J. Mitchell, Robert Tjian Science
  2. Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements (1987)
    Pamela J. Mitchell, Robert Tjian et al. Cell
  3. Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain (1987)
    James T. Kadonaga, Frank R. Masiarz et al. Cell
  4. Purification and Biochemical Characterization of the Promoter-Specific Transcription Factor, Sp1 (1986)
    Michael R. Briggs, James T. Kadonaga et al. Science
  5. The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter (1983)
    William S. Dynan, Robert Tjian Cell
  6. Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif (1988)
    Albert J. Courey, Robert Tjian Cell
  7. Human Proto-Oncogene c- jun Encodes a DNA Binding Protein with Structural and Functional Properties of Transcription Factor AP-1 (1987)
    Dirk Bohmann, Timothy J. Bos et al. Science
  8. Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins (1985)
    William S. Dynan, Robert Tjian Nature
  9. Affinity purification of sequence-specific DNA binding proteins. (1986)
    James T. Kadonaga, Robert Tjian Proceedings of the National Academy of Sciences
  10. A cellular DNA-binding protein that activates eukaryotic transcription and DNA replication (1987)
    Katherine A. Jones, James T. Kadonaga et al. Cell
  11. Transcriptional activation: A complex puzzle with few easy pieces (1994)
    Robert Tjian, Tom Maniatis Cell
  12. Promoter-specific activation of RNA polymerase II transcription by Sp1 (1986)
    James T. Kadonaga, Katherine A. Jones et al. Trends in Biochemical Sciences
  13. Mechanism of transcriptional activation by Sp1: Evidence for coactivators (1990)
    Robert Tjian et al. Cell
  14. Positive and negative regulation of transcription in vitro: Enhancer-binding protein AP-2 is inhibited by SV40 T antigen (1987)
    Pamela J. Mitchell, Charlotte Wang et al. Cell
  15. Transcription regulation and animal diversity (2003)
    Michael Levine, Robert Tjian Nature
  16. Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection (2016)
    Alexandra East-Seletsky, Mitchell R. O’Connell et al. Nature
  17. O-glycosylation of eukaryotic transcription factors: Implications for mechanisms of transcriptional regulation (1988)
    Stephen P. Jackson, Robert Tjian Cell
  18. Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro (1985)
    Katherine A. Jones, Keith R. Yamamoto et al. Cell
  19. The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain (1989)
    Nicolas Mermod, Edward A. O’Neill et al. Cell
  20. Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II (1983)
    William S. Dynan, Robert Tjian Cell
  21. A family of human CCAAT-box-binding proteins active in transcription and DNA replication: cloning and expression of multiple cDNAs (1988)
    Claudio Santoro, Nicolas Mermod et al. Nature
  22. Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40 (1987)
    Alois Haslinger, Michael Karin et al. Nature
  23. Transcriptional selectivity of viral genes in mammalian cells (1986)
    Steven L. McKnight, Robert Tjian Cell
  24. Structure and Function of a Human TAF II 250 Double Bromodomain Module (2000)
    Raymond H. Jacobson, Andreas G. Ladurner et al. Science
  25. Imaging dynamic and selective low-complexity domain interactions that control gene transcription (2018)
    Shasha Chong, Claire Dugast‐Darzacq et al. Science
  26. Activation of the AIDS Retrovirus Promoter by the Cellular Transcription Factor, Sp1 (1986)
    Katherine A. Jones, James T. Kadonaga et al. Science
  27. Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation (1991)
    Brian David Dynlacht, Timothy Hoey et al. Cell
  28. GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase (1990)
    Stephen P. Jackson, Susan P. Lees‐Miller et al. Cell
  29. Leucine Repeats and an Adjacent DNA Binding Domain Mediate the Formation of Functional cFos-cJun Heterodimers (1989)
    Richard Turner, Robert Tjian Science
  30. The activities of two Ets-related transcription factors required for drosophila eye development are modulated by the Ras/MAPK pathway (1994)
    Elizabeth O’Neill, Ilaria Rebay et al. Cell
  31. Orchestrated response: a symphony of transcription factors for gene control (2000)
    Bryan D. Lemon, Robert Tjian Genes & Development
  32. Fos-Associated Protein p39 Is the Product of the jun Proto-Oncogene (1988)
    Frank J. Rauscher, Donna Cohén et al. Science
  33. Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins (1990)
    Hans‐Michael Jantzen, Arie Admon et al. Nature
  34. Transcription from a TATA-less promoter requires a multisubunit TFIID complex. (1991)
    B. Franklin Pugh, Robert Tjian Genes & Development
  35. Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis. (1991)
    Pamela J. Mitchell, Jean M. Hébert et al. Genes & Development
  36. Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators (1993)
    Timothy Hoey, Robert O. J. Weinzierl et al. Cell
  37. Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements. (1988)
    Trevor Williams, Arie Admon et al. Genes & Development
  38. Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway (2003)
    Óscar Puig, Michael T. Marr et al. Genes & Development
  39. Multiple specific contacts between a mammalian transcription factor and its cognate promoters (1984)
    David Gidoni, William S. Dynan et al. Nature
  40. The binding site on SV40 DNA for a T antigen-related protein (1978)
    Robert Tjian Cell
  41. Single-Molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells (2014)
    Jiji Chen, Zhengjian Zhang et al. Cell
  42. Evaluating phase separation in live cells: diagnosis, caveats, and functional consequences (2019)
    David T. McSwiggen, Mustafa Mir et al. Genes & Development
  43. CTCF and cohesin regulate chromatin loop stability with distinct dynamics (2017)
    Anders S. Hansen, Iryna Pustova et al. eLife
  44. Resolving the 3D Landscape of Transcription-Linked Mammalian Chromatin Folding (2020)
    Tsung-Han S. Hsieh, Claudia Cattoglio et al. Molecular Cell
  45. Dynamics of CRISPR-Cas9 genome interrogation in living cells (2015)
    Spencer C. Knight, Liangqi Xie et al. Science
  46. Enhancer–promoter interactions and transcription are largely maintained upon acute loss of CTCF, cohesin, WAPL or YY1 (2022)
    Tsung-Han S. Hsieh, Claudia Cattoglio et al. Nature Genetics

Immediate Impact

54 by Nobel laureates 91 from Science/Nature 149 standout
Sub-graph 1 of 18

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27 intermediate papers

Works of Robert Tjian being referenced

Real-time imaging of Huntingtin aggregates diverting target search and gene transcription
2016 Nobel
Structure and Function of a Human TAF II 250 Double Bromodomain Module
2000 StandoutScience
and 7 more

Author Peers

Author Last Decade Papers Cites
Robert Tjian 55642 13805 8038 336 69.0k
Andrew P. Feinberg 44543 15391 5849 233 61.5k
Feng Zhang 74434 14566 4487 177 82.9k
William J. Rutter 35291 9762 5424 309 56.5k
J. Michael Bishop 32788 11396 9463 356 48.3k
C. David Allis 76506 9541 5621 343 86.7k
Robert G. Roeder 50838 10263 5794 530 61.4k
Richard A. Young 58343 7510 6037 279 69.2k
Phillip A. Sharp 75784 17227 7216 428 91.6k
Philip Leder 40876 10441 11779 351 63.1k
L. Aravind 38903 8906 3047 377 51.6k

All Works

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