Standout Papers

Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells 2004 2026 2011 2018 3.4k
  1. Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells (2005)
    Laurie A. Boyer, Tong Ihn Lee et al. Cell
  2. Histone H3K27ac separates active from poised enhancers and predicts developmental state (2010)
    Menno P. Creyghton, Albert W. Cheng et al. Proceedings of the National Academy of Sciences
  3. Polycomb complexes repress developmental regulators in murine embryonic stem cells (2006)
    Laurie A. Boyer, Kathrin Plath et al. Nature
  4. Transcriptional regulatory code of a eukaryotic genome (2004)
    Christopher Harbison, Tong Ihn Lee et al. Nature
  5. A Chromatin Landmark and Transcription Initiation at Most Promoters in Human Cells (2007)
    Matthew G. Guenther, Stuart S. Levine et al. Cell
  6. Dissecting the Regulatory Circuitry of a Eukaryotic Genome (1998)
    Frank C. P. Holstege, Ezra G. Jennings et al. Cell
  7. Mediator and cohesin connect gene expression and chromatin architecture (2010)
    Michael H. Kagey, Jamie J. Newman et al. Nature
  8. Genome-Wide Location and Function of DNA Binding Proteins (2000)
    Bing Ren, François Robert et al. Science
  9. Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains (2018)
    Ann Boija, Isaac A. Klein et al. Cell
  10. A Phase Separation Model for Transcriptional Control (2017)
    Denes Hnisz, Krishna Shrinivas et al. Cell
  11. Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells (2008)
    Alexander Marson, Stuart S. Levine et al. Cell
  12. Transcriptional Amplification in Tumor Cells with Elevated c-Myc (2012)
    Charles Y. Lin, Jakob Lovén et al. Cell
  13. Genome-wide Map of Nucleosome Acetylation and Methylation in Yeast (2005)
    Dmitry Pokholok, Christopher Harbison et al. Cell
  14. Remodeling of Yeast Genome Expression in Response to Environmental Changes (2001)
    Helen C. Causton, Bing Ren et al. Molecular Biology of the Cell
  15. Control of Pancreas and Liver Gene Expression by HNF Transcription Factors (2004)
    Duncan T. Odom, Nora Zizlsperger et al. Science
  16. Transcriptional Regulation and Its Misregulation in Disease (2013)
    Tong Ihn Lee, Richard A. Young Cell
  17. Stem Cells, the Molecular Circuitry of Pluripotency and Nuclear Reprogramming (2008)
    Rudolf Jaenisch, Richard A. Young Cell
  18. Yeast RNA Polymerase II Genes: Isolation with Antibody Probes (1983)
    Richard A. Young, Ronald W. Davis Science
  19. c-Myc Regulates Transcriptional Pause Release (2010)
    Peter B. Rahl, Charles Y. Lin et al. Cell
  20. E2F integrates cell cycle progression with DNA repair, replication, and G 2 /M checkpoints (2002)
    Bing Ren, Yasuhiko Takahashi et al. Genes & Development
  21. Targeted Recruitment of Set1 Histone Methylase by Elongating Pol II Provides a Localized Mark and Memory of Recent Transcriptional Activity (2003)
    Huck‐Hui Ng, François Robert et al. Molecular Cell
  22. Editing DNA Methylation in the Mammalian Genome (2016)
    X. Shawn Liu, Hao Wu et al. Cell
  23. Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues (2005)
    Xinmin Zhang, Duncan T. Odom et al. Proceedings of the National Academy of Sciences
  24. Transcriptional Addiction in Cancer (2017)
    James E. Bradner, Denes Hnisz et al. Cell
  25. Divergent Transcription from Active Promoters (2008)
    J. Mauro Calabrese, Stuart S. Levine et al. Science
  26. Activation of proto-oncogenes by disruption of chromosome neighborhoods (2016)
    Denes Hnisz, Abraham S. Weintraub et al. Science
  27. Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity (2013)
    Christine L. Chaffer, Nemanja D. Marjanovic et al. Cell
  28. YY1 Is a Structural Regulator of Enhancer-Promoter Loops (2017)
    Abraham S. Weintraub, Charles H. Li et al. Cell
  29. NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth (2006)
    Teresa Palomero, Wei Keat Lim et al. Proceedings of the National Academy of Sciences
  30. TRANSCRIPTION OF EUKARYOTIC PROTEIN-CODING GENES (2000)
    Tong Ihn Lee, Richard A. Young Annual Review of Genetics
  31. RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo (2007)
    Julia Zeitlinger, Alexander Stark et al. Nature Genetics
  32. The Plasticity of Dendritic Cell Responses to Pathogens and Their Components (2001)
    Qian Huang, Dongyu Liu et al. Science
  33. Chromatin immunoprecipitation and microarray-based analysis of protein location (2006)
    Tong Ihn Lee, Sarah E. Johnstone et al. Nature Protocols
  34. Foxp3 occupancy and regulation of key target genes during T-cell stimulation (2007)
    Alexander Marson, Karsten Kretschmer et al. Nature
  35. Human macrophage activation programs induced by bacterial pathogens (2002)
    Gerard J. Nau, Ann Schlesinger et al. Proceedings of the National Academy of Sciences
  36. Discovery and Characterization of Super-Enhancer-Associated Dependencies in Diffuse Large B Cell Lymphoma (2013)
    Bjoern Chapuy, Michael R. McKeown et al. Cancer Cell
  37. An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element (2014)
    Marc R. Mansour, Brian J. Abraham et al. Science
  38. CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancer (2014)
    Edmond Chipumuro, Eugenio Marco et al. Cell
  39. Pol II phosphorylation regulates a switch between transcriptional and splicing condensates (2019)
    Yang Guo, John C. Manteiga et al. Nature
  40. Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation (2017)
    Heike Brötz‐Oesterhelt, Baishan Jiang et al. Nature Chemical Biology
  41. Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression (2016)
    Frank Soldner, Yonatan Stelzer et al. Nature
  42. RNA-Mediated Feedback Control of Transcriptional Condensates (2020)
    Jonathan E. Henninger, Ozgur Oksuz et al. Cell
  43. Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene (2018)
    X. Shawn Liu, Hao Wu et al. Cell
  44. Biomolecular Condensates in the Nucleus (2020)
    Benjamin R. Sabari, Alessandra Dall’Agnese et al. Trends in Biochemical Sciences
  45. Biomolecular Condensates and Cancer (2021)
    Ann Boija, Isaac A. Klein et al. Cancer Cell
  46. Transcription factors interact with RNA to regulate genes (2023)
    Ozgur Oksuz, Jonathan E. Henninger et al. Molecular Cell

Immediate Impact

30 by Nobel laureates 54 from Science/Nature 150 standout
Sub-graph 1 of 12

Citing Papers

The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
10 intermediate papers

Works of Richard A. Young being referenced

A Phase Separation Model for Transcriptional Control
2017 Standout
Polycomb complexes repress developmental regulators in murine embryonic stem cells
2006 StandoutNature
and 8 more

Author Peers

Author Last Decade Papers Cites
Richard A. Young 58343 6095 7510 7076 279 69.2k
C. David Allis 76506 5197 9541 5037 343 86.7k
Andrew P. Feinberg 44543 4373 15391 6693 233 61.5k
Hediye Erdjument‐Bromage 52815 6857 5421 5909 283 67.2k
Robert Tjian 55642 6778 13805 4183 336 69.0k
Robert G. Roeder 50838 6609 10263 4743 530 61.4k
Paul Tempst 61550 8945 6470 7571 320 79.9k
Tony Kouzarides 44255 3887 6470 5378 176 53.1k
J. Michael Bishop 32788 5694 11396 5067 356 48.3k
Richard A. Lempicki 36036 8421 7420 10828 125 59.5k
T Gingeras 32513 7579 6790 8263 129 50.0k

All Works

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2026