Standout Papers

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-diges... 1977 2026 1993 2009 2.8k
  1. Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids (1977)
    Arnold Berk, Phillip A. Sharp Cell
  2. Histone H3K27ac separates active from poised enhancers and predicts developmental state (2010)
    Menno P. Creyghton, Albert W. Cheng et al. Proceedings of the National Academy of Sciences
  3. In vivo genome editing using Staphylococcus aureus Cas9 (2015)
    F. Ann Ran, Le Cong et al. Nature
  4. RNAi (2000)
    Phillip D. Zamore, Thomas Tuschl et al. Cell
  5. MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells (2007)
    Margaret S. Ebert, Joel R. Neilson et al. Nature Methods
  6. Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose-ethidium bromide electrophoresis (1973)
    Phillip A. Sharp, Bill Sugden et al. Biochemistry
  7. Targeted Deletion Reveals Essential and Overlapping Functions of the miR-17∼92 Family of miRNA Clusters (2008)
    Andrea Ventura, Amanda Young et al. Cell
  8. Specificity of microRNA target selection in translational repression (2004)
    John G. Doench, Phillip A. Sharp Genes & Development
  9. Roles for MicroRNAs in Conferring Robustness to Biological Processes (2012)
    Margaret S. Ebert, Phillip A. Sharp Cell
  10. SPLICING OF MESSENGER RNA PRECURSORS (1986)
    Richard A. Padgett, Paula J. Grabowski et al. Annual Review of Biochemistry
  11. DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract. (1980)
    James L. Manley, Andrew Fire et al. Proceedings of the National Academy of Sciences
  12. A Phase Separation Model for Transcriptional Control (2017)
    Denes Hnisz, Krishna Shrinivas et al. Cell
  13. Lentivirus-delivered stable gene silencing by RNAi in primary cells (2003)
    Sheila A. Stewart, Derek M. Dykxhoorn et al. RNA
  14. Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells (2008)
    Alexander Marson, Stuart S. Levine et al. Cell
  15. A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes (1986)
    Harinder Singh, Ranjan Sen et al. Nature
  16. Gene silencing in mammals by small interfering RNAs (2002)
    Michael T. McManus, Phillip A. Sharp Nature Reviews Genetics
  17. Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites (2008)
    Rickard Sandberg, Joel R. Neilson et al. Science
  18. c-Myc Regulates Transcriptional Pause Release (2010)
    Peter B. Rahl, Charles Y. Lin et al. Cell
  19. siRNAs can function as miRNAs (2003)
    John G. Doench, Christian P. Petersen et al. Genes & Development
  20. Five intermediate complexes in transcription initiation by RNA polymerase II (1989)
    Stephen Buratowski, Steven Hahn et al. Cell
  21. Spliced segments at the 5′ terminus of adenovirus 2 late mRNA (1977)
    Susan M. Berget, Claire Moore et al. Proceedings of the National Academy of Sciences
  22. Killing the messenger: short RNAs that silence gene expression (2003)
    Derek M. Dykxhoorn, Carl D. Novina et al. Nature Reviews Molecular Cell Biology
  23. Embryonic Stem Cell-Specific MicroRNAs (2003)
    Hristo B Houbaviy, Michael F. Murray et al. Developmental Cell
  24. Splicing of Messenger RNA Precursors (1987)
    Phillip A. Sharp Science
  25. TAZ, a Transcriptional Modulator of Mesenchymal Stem Cell Differentiation (2005)
    Jeong‐Ho Hong, Eun Sook Hwang et al. Science
  26. Predictive Identification of Exonic Splicing Enhancers in Human Genes (2002)
    William G. Fairbrother, Ru‐Fang Yeh et al. Science
  27. Spliced early mRNAs of simian virus 40 (1978)
    Arnold Berk, Phillip A. Sharp Proceedings of the National Academy of Sciences
  28. An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter (1985)
    Richard W. Carthew, Lewis A. Chodosh et al. Cell
  29. Suppression of non-small cell lung tumor development by the let-7 microRNA family (2008)
    Madhu Kumar, Stefan J. Erkeland et al. Proceedings of the National Academy of Sciences
  30. Divergent Transcription from Active Promoters (2008)
    J. Mauro Calabrese, Stuart S. Levine et al. Science
  31. Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs (1979)
    Arnold Berk, Frank Lee et al. Cell
  32. MicroRNA Functions in Stress Responses (2010)
    Anthony K. L. Leung, Phillip A. Sharp Molecular Cell
  33. A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes (1986)
    Louis M. Staudt, Harinder Singh et al. Nature
  34. Human CCAAT-binding proteins have heterologous subunits (1988)
    Lewis A. Chodosh, Albert S. Baldwin et al. Cell
  35. The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. (1988)
    Winship Herr, Richard A. Sturm et al. Genes & Development
  36. Targeted mRNA degradation by double-stranded RNA in vitro (1999)
    Thomas Tuschl, Phillip D. Zamore et al. Genes & Development
  37. siRNA-directed inhibition of HIV-1 infection (2002)
    Carl D. Novina, Michael F. Murray et al. Nature Medicine
  38. Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis (2015)
    Sidi Chen, Neville E. Sanjana et al. Cell
  39. Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132 (2010)
    Dieter Edbauer, Joel R. Neilson et al. Neuron
  40. MicroRNA sponges: Progress and possibilities (2010)
    Margaret S. Ebert, Phillip A. Sharp RNA
  41. A High-Efficiency HeLa Cell Nuclear Transcription Extract (1988)
    David J. Shapiro, Phillip A. Sharp et al. DNA
  42. Molecular cloning of an enhancer binding protein:Isolation by screening of an expression library with a recognition site DNA (1988)
    Harinder Singh, Jonathan H. LeBowitz et al. Cell
  43. RNA interference—2001 (2001)
    Phillip A. Sharp Genes & Development
  44. Speculations on RNA splicing (1981)
    Phillip A. Sharp Cell
  45. CRISPR-mediated direct mutation of cancer genes in the mouse liver (2014)
    Wen Xue, Sidi Chen et al. Nature
  46. The RNAi revolution (2004)
    Carl D. Novina, Phillip A. Sharp Nature
  47. Structure of the adenovirus 2 early mRNAs (1978)
    Arnold Berk, Phillip A. Sharp Cell
  48. Short RNAs Repress Translation after Initiation in Mammalian Cells (2006)
    Christian P. Petersen, Jerry Pelletier et al. Molecular Cell
  49. Recognition of cap structure in splicing in vitro of mRNA precursors (1984)
    Maria M. Konarska, Richard A. Padgett et al. Cell
  50. Pol II phosphorylation regulates a switch between transcriptional and splicing condensates (2019)
    Yang Guo, John C. Manteiga et al. Nature
  51. Viral DNA in transformed cells (1974)
    P. H. Gallimore, Phillip A. Sharp et al. Journal of Molecular Biology
  52. RNA-Mediated Feedback Control of Transcriptional Condensates (2020)
    Jonathan E. Henninger, Ozgur Oksuz et al. Cell
  53. [35] In Vitro transcription: Whole-cell extract (1983)
    James L. Manley, Andrew Fire et al. Methods in enzymology on CD-ROM/Methods in enzymology
  54. Separation and characterization of factors mediating accurate transcription by RNA polymerase II. (1982)
    Mark Samuels, Andrew Fire et al. Journal of Biological Chemistry

Immediate Impact

130 by Nobel laureates 159 from Science/Nature 353 standout
Sub-graph 1 of 18

Citing Papers

CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
9 intermediate papers

Works of Phillip A. Sharp being referenced

In vivo genome editing using Staphylococcus aureus Cas9
2015 StandoutNature
CRISPR-mediated direct mutation of cancer genes in the mouse liver
2014 StandoutNature
and 3 more

Author Peers

Author Last Decade Papers Cites
Phillip A. Sharp 75784 17227 18542 428 91.6k
Chris Sander 67938 8129 25841 304 90.9k
Nahum Sonenberg 75137 8424 12574 664 94.7k
Aviv Regev 59947 6210 19997 319 77.9k
Rudolf Jaenisch 105873 32767 13861 585 134.8k
Gregory J. Hannon 83531 10278 34690 320 103.4k
Robert Tjian 55642 13805 4183 336 69.0k
Inder M. Verma 43317 18652 12973 399 68.3k
Richard A. Young 58343 7510 7076 279 69.2k
Thomas A. Kunkel 41800 9012 8331 402 51.5k
Thomas Tuschl 60757 5259 34157 219 74.0k

All Works

Loading papers...

Rankless by CCL
2026