Standout Papers

Gene expression profiling predicts clinical outcome of breast cancer... 1994 2026 2004 2015 6.8k
  1. Gene expression profiling predicts clinical outcome of breast cancer (2002)
    Laura van ‘t Veer, Hongyue Dai et al. Nature
  2. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs (2005)
    Lee P. Lim, Nelson C. Lau et al. Nature
  3. A microRNA component of the p53 tumour suppressor network (2007)
    Lin He, Xingyue He et al. Nature
  4. Expression profiling reveals off-target gene regulation by RNAi (2003)
    Aimee L. Jackson, Steven R. Bartz et al. Nature Biotechnology
  5. CTLA-4 can function as a negative regulator of T cell activation (1994)
    Theresa L. Walunas, Deborah J. Lenschow et al. Immunity
  6. CTLA-4 and PD-1 Receptors Inhibit T-Cell Activation by Distinct Mechanisms (2005)
    Richard V. Parry, Jens M. Chemnitz et al. Molecular and Cellular Biology
  7. MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data (2015)
    Greg Finak, Andrew McDavid et al. Genome biology
  8. CTLA-4 is a second receptor for the B cell activation antigen B7. (1991)
    Peter S. Linsley, William Brady et al. The Journal of Experimental Medicine
  9. Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways (1996)
    Christian P. Larsen, Eric T. Elwood et al. Nature
  10. Genetics of gene expression surveyed in maize, mouse and man (2003)
    Eric E. Schadt, Stephanie A. Monks et al. Nature
  11. Long-Term Survival of Xenogeneic Pancreatic Islet Grafts Induced by CTLA4lg (1992)
    Deborah J. Lenschow, Yijun Zeng et al. Science
  12. Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4 (1992)
    Lieping Chen, William Brady et al. Cell
  13. A large-scale RNAi screen in human cells identifies new components of the p53 pathway (2004)
    Katrien Berns, E. Marielle Hijmans et al. Nature Cell Biology
  14. Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application (2009)
    Aimee L. Jackson, Peter S. Linsley Nature Reviews Drug Discovery
  15. Widespread siRNA “off-target” transcript silencing mediated by seed region sequence complementarity (2006)
    Aimee L. Jackson, Julja Burchard et al. RNA
  16. IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression. (1993)
    Linna Ding, Peter S. Linsley et al. The Journal of Immunology
  17. MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators (2008)
    Galina Gabriely, Thomas Würdinger et al. Molecular and Cellular Biology
  18. miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice (2011)
    Mark Boldin, Konstantin D. Taganov et al. The Journal of Experimental Medicine
  19. Immunosuppression in Vivo by a Soluble Form of the CTLA-4 T Cell Activation Molecule (1992)
    Peter S. Linsley, Philip M. Wallace et al. Science
  20. T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1. (1990)
    Peter S. Linsley, Edward A. Clark et al. Proceedings of the National Academy of Sciences
  21. Position-specific chemical modification of siRNAs reduces “off-target” transcript silencing (2006)
    Aimee L. Jackson, Julja Burchard et al. RNA
  22. Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function. (1994)
    Karen S. Hathcock, Glória László et al. The Journal of Experimental Medicine
  23. Role of the CD28 receptor in T-cell activation (1990)
    Carl H. June, Jeffrey A. Ledbetter et al. Immunology Today
  24. Treatment of Murine Lupus with CTLA4Ig (1994)
    Brian N. Finck, Peter S. Linsley et al. Science
  25. Rational Development of LEA29Y (belatacept), a High-Affinity Variant of CTLA4-Ig with Potent Immunosuppressive Properties (2005)
    Christian P. Larsen, Thomas C. Pearson et al. American Journal of Transplantation
  26. The tissue distribution of the B7-2 costimulator in mice: abundant expression on dendritic cells in situ and during maturation in vitro. (1994)
    Kensuke Inaba, Margit D. Witmer-Pack et al. The Journal of Experimental Medicine

Immediate Impact

81 by Nobel laureates 65 from Science/Nature 228 standout
Sub-graph 1 of 15

Citing Papers

Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH+
2019 StandoutNature
20 intermediate papers

Works of Peter S. Linsley being referenced

MAST: a flexible statistical framework for assessing transcriptional changes and characterizing heterogeneity in single-cell RNA sequencing data
2015 Standout
Interaction of the Cytoplasmic Tail of CTLA-4 (CD152) with a Clathrin-Associated Protein Is Negatively Regulated by Tyrosine Phosphorylation
1997
and 14 more

Author Peers

Author Last Decade Papers Cites
Peter S. Linsley 22604 24497 6544 12729 274 54.5k
David V. Goeddel 24057 34538 4745 16576 192 64.2k
Klaus Rajewsky 41459 29827 6582 10370 502 76.4k
James Darnell 22541 40025 9006 8268 356 72.5k
Inder M. Verma 13348 43317 18652 12973 399 68.3k
Ettore Appella 17042 33099 4339 6373 549 54.1k
Frances R. Balkwill 18138 13853 2064 9511 291 46.0k
Frederick W. Alt 26758 41129 5915 6786 482 72.9k
Stanley J. Korsmeyer 15078 59060 4175 7600 230 83.2k
Peter H. Krammer 19633 29654 2083 6620 426 47.4k
Stuart A. Aaronson 6399 27751 9308 4319 430 45.4k

All Works

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