Standout Papers

Cluster analysis and display of genome-wide expression patterns 1995 2026 2005 2015 12.1k
  1. Cluster analysis and display of genome-wide expression patterns (1998)
    Michael B. Eisen, Paul T. Spellman et al. Proceedings of the National Academy of Sciences
  2. Molecular portraits of human breast tumours (2000)
    Charles M. Perou, Thérese Sørlie et al. Nature
  3. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications (2001)
    Thérese Sørlie, Charles M. Perou et al. Proceedings of the National Academy of Sciences
  4. Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray (1995)
    Mark Schena, Dari Shalon et al. Science
  5. Repeated observation of breast tumor subtypes in independent gene expression data sets (2003)
    Thérese Sørlie, Robert Tibshirani et al. Proceedings of the National Academy of Sciences
  6. Genomic Expression Programs in the Response of Yeast Cells to Environmental Changes (2000)
    Audrey P. Gasch, Paul T. Spellman et al. Molecular Biology of the Cell
  7. Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale (1997)
    Joseph L. DeRisi, Vishwanath R. Iyer et al. Science
  8. Comprehensive Identification of Cell Cycle–regulated Genes of the YeastSaccharomyces cerevisiaeby Microarray Hybridization (1998)
    Paul T. Spellman, Gavin Sherlock et al. Molecular Biology of the Cell
  9. Development of the Human Infant Intestinal Microbiota (2007)
    Chana Palmer, Elisabeth M. Bik et al. PLoS Biology
  10. Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types (2012)
    Julia Salzman, Charles Gawad et al. PLoS ONE
  11. Exploring the new world of the genome with DNA microarrays (1999)
    Patrick O. Brown, David Botstein Nature Genetics
  12. Systematic variation in gene expression patterns in human cancer cell lines (2000)
    Douglas T. Ross, Uwe Scherf et al. Nature Genetics
  13. The Transcriptional Program in the Response of Human Fibroblasts to Serum (1999)
    Vishwanath R. Iyer, Michael B. Eisen et al. Science
  14. Cell-Type Specific Features of Circular RNA Expression (2013)
    Julia Salzman, Raymond Chen et al. PLoS Genetics
  15. Use of a cDNA microarray to analyse gene expression patterns in human cancer (1996)
    Joseph L. DeRisi, Lolita Penland et al. Nature Genetics
  16. The Transcriptional Program of Sporulation in Budding Yeast (1998)
    Joseph L. DeRisi, Michael B. Eisen et al. Science
  17. Singular value decomposition for genome-wide expression data processing and modeling (2000)
    Orly Alter, Patrick O. Brown et al. Proceedings of the National Academy of Sciences
  18. Identification of Genes Periodically Expressed in the Human Cell Cycle and Their Expression in Tumors (2002)
    Michael L. Whitfield, Gavin Sherlock et al. Molecular Biology of the Cell
  19. Genome-wide analysis of DNA copy-number changes using cDNA microarrays (1999)
    Jonathan R. Pollack, Charles M. Perou et al. Nature Genetics
  20. Distinctive gene expression patterns in human mammary epithelial cells and breast cancers (1999)
    Charles M. Perou, Stefanie S. Jeffrey et al. Proceedings of the National Academy of Sciences
  21. A gene expression database for the molecular pharmacology of cancer (2000)
    Uwe Scherf, Douglas T. Ross et al. Nature Genetics
  22. Diversity of gene expression in adenocarcinoma of the lung (2001)
    Mitchell Garber, Olga G. Troyanskaya et al. Proceedings of the National Academy of Sciences
  23. Gene expression profiling identifies clinically relevant subtypes of prostate cancer (2004)
    Jacques Lapointe, Chunde Li et al. Proceedings of the National Academy of Sciences
  24. Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors (2002)
    Jonathan R. Pollack, Thérese Sørlie et al. Proceedings of the National Academy of Sciences
  25. Diversity, topographic differentiation, and positional memory in human fibroblasts (2002)
    Howard Y. Chang, Jen‐Tsan Chi et al. Proceedings of the National Academy of Sciences
  26. Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF (2001)
    Vishwanath R. Iyer, Christine E. Horak et al. Nature
  27. Relation of Gene Expression Phenotype to Immunoglobulin Mutation Genotype in B Cell Chronic Lymphocytic Leukemia (2001)
    Andreas Rosenwald, Ash A. Alizadeh et al. The Journal of Experimental Medicine
  28. [12] DNA arrays for analysis of gene expression (1999)
    Michael B. Eisen, Patrick O. Brown Methods in enzymology on CD-ROM/Methods in enzymology
  29. A DNA microarray system for analyzing complex DNA samples using two-color fluorescent probe hybridization. (1996)
    Dari Shalon, Steven J. Smith et al. Genome Research
  30. Integration of murine leukemia virus DNA depends on mitosis. (1993)
    Thomas C. Reynolds, Patrick O. Brown et al. The EMBO Journal
  31. Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival (2005)
    Howard Y. Chang, Dimitry S.A. Nuyten et al. Proceedings of the National Academy of Sciences
  32. Gene Expression Signature of Fibroblast Serum Response Predicts Human Cancer Progression: Similarities between Tumors and Wounds (2004)
    Howard Y. Chang, Julie B. Sneddon et al. PLoS Biology
  33. Gene Expression Patterns in Human Liver Cancers (2002)
    Xin Chen, ST Cheung et al. Molecular Biology of the Cell
  34. Protein microarrays for highly parallel detection and quantitation of specific proteins and antibodies in complex solutions (2001)
    Brian B. Haab, Maitreya J. Dunham et al. Genome biology
  35. Comparative Gene Expression Profiles Following UV Exposure in Wild-Type and SOS-Deficient Escherichia coli (2001)
    Justin Courcelle, Arkady Khodursky et al. Genetics
  36. Individuality and variation in gene expression patterns in human blood (2003)
    Adeline R. Whitney, Maximilian Diehn et al. Proceedings of the National Academy of Sciences
  37. Circular RNA Is Expressed across the Eukaryotic Tree of Life (2014)
    Peter L. Wang, Yun Bao et al. PLoS ONE
  38. Endothelial cell diversity revealed by global expression profiling (2003)
    Jen‐Tsan Chi, Howard Y. Chang et al. Proceedings of the National Academy of Sciences
  39. Precision and functional specificity in mRNA decay (2002)
    Yulei Wang, Chih Long Liu et al. Proceedings of the National Academy of Sciences
  40. Promoter-specific binding of Rap1 revealed by genome-wide maps of protein–DNA association (2001)
    Jason D. Lieb, David Botstein et al. Nature Genetics
  41. Extensive Association of Functionally and Cytotopically Related mRNAs with Puf Family RNA-Binding Proteins in Yeast (2004)
    André P. Gerber, Daniel Herschlag et al. PLoS Biology
  42. Genome-wide analysis of mRNA translation profiles in Saccharomyces cerevisiae (2003)
    Yoav Arava, Yulei Wang et al. Proceedings of the National Academy of Sciences
  43. Gene expression patterns in human embryonic stem cells and human pluripotent germ cell tumors (2003)
    Jamie M. Sperger, Xin Chen et al. Proceedings of the National Academy of Sciences
  44. Genome-wide analysis of DNA copy number variation in breast cancer using DNA microarrays (1999)
    Jonathan R. Pollack, Charles M. Perou et al. Nature Genetics
  45. Autoantigen microarrays for multiplex characterization of autoantibody responses (2002)
    William H. Robinson, Wolfgang Hueber et al. Nature Medicine
  46. The Novel Marker, DOG1, Is Expressed Ubiquitously in Gastrointestinal Stromal Tumors Irrespective of KIT or PDGFRA Mutation Status (2004)
    Robert B. West, Christopher L. Corless et al. American Journal Of Pathology
  47. Drug target validation and identification of secondary drug target effects using DNA microarrays (1998)
    Matthew J. Marton, Joseph L. DeRisi et al. Nature Medicine
  48. Correct integration of retroviral DNA in vitro (1987)
    Patrick O. Brown, Bruce Bowerman et al. Cell
  49. Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein. (1989)
    Patrick O. Brown, Bruce Bowerman et al. Proceedings of the National Academy of Sciences
  50. A nucleoprotein complex mediates the integration of retroviral DNA. (1989)
    Bruce Bowerman, Patrick O. Brown et al. Genes & Development

Immediate Impact

22 by Nobel laureates 47 from Science/Nature 121 standout
Sub-graph 1 of 15

Citing Papers

Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2021 Standout
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
12 intermediate papers

Works of Patrick O. Brown being referenced

Stereospecificity of Reactions Catalyzed by HIV-1 Integrase
1999
Reversal of Integration and DNA Splicing Mediated by Integrase of Human Immunodeficiency Virus
1992 Science
and 12 more

Author Peers

Author Last Decade Papers Cites
Patrick O. Brown 82551 14464 3124 24176 19771 266 117.1k
Chris Sander 67938 8129 547 25841 13143 304 90.9k
Gordon K. Smyth 68030 12841 677 20147 13829 333 118.5k
David Botstein 106977 27481 343 22439 20132 413 156.4k
Stephen J. Elledge 75009 9992 1691 13658 27392 360 91.4k
Arnold J. Levine 59816 11469 768 15872 45342 437 88.9k
Douglas Hanahan 78402 13213 219 35907 43041 224 134.4k
Jill P. Mesirov 49254 7255 373 14867 11689 128 75.7k
Todd R. Golub 73850 7152 336 27046 18530 227 109.1k
Wolfgang Huber 64845 12160 557 14172 6843 228 105.3k
Minoru Kanehisa 73697 9876 347 11792 5206 253 109.5k

All Works

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2026