Standout Papers

Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles 2000 2026 2008 2017 3.2k
  1. Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles (2003)
    Salvatore Oddo, Antonella Caccamo et al. Neuron
  2. Pathways towards and away from Alzheimer's disease (2004)
    Mark P. Mattson Nature
  3. Self-Propagating, Molecular-Level Polymorphism in Alzheimer's ß-Amyloid Fibrils (2005)
    Aneta T. Petkova, Richard D. Leapman et al. Science
  4. Apoptosis in neurodegenerative disorders (2000)
    Mark P. Mattson Nature Reviews Molecular Cell Biology
  5. Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease (2019)
    Evandro Fei Fang, Yujun Hou et al. Nature Neuroscience
  6. Fasting: Molecular Mechanisms and Clinical Applications (2014)
    Valter D. Longo, Mark P. Mattson Cell Metabolism
  7. A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease. (1994)
    K. Hensley, John M. Carney et al. Proceedings of the National Academy of Sciences
  8. Effects of Intermittent Fasting on Health, Aging, and Disease (2019)
    Rafael de Cabo, Mark P. Mattson New England Journal of Medicine
  9. Hormesis defined (2007)
    Mark P. Mattson Ageing Research Reviews
  10. Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease (2004)
    Roy G. Cutler, Jeremiah Kelly et al. Proceedings of the National Academy of Sciences
  11. Mitochondria in Neuroplasticity and Neurological Disorders (2008)
    Mark P. Mattson, Marc Gleichmann et al. Neuron
  12. Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives (1997)
    Mark P. Mattson Physiological Reviews
  13. Ageing and neuronal vulnerability (2006)
    Mark P. Mattson, Tim Magnus Nature reviews. Neuroscience
  14. Evidence that brain‐derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice (2002)
    Jaewon Lee, Wenzhen Duan et al. Journal of Neurochemistry
  15. Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors (1996)
    Annadora J. Bruce, Warren Boling et al. Nature Medicine
  16. BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders (2004)
    Mark P. Mattson, Stuart Maudsley et al. Trends in Neurosciences
  17. NF-κB in neuronal plasticity and neurodegenerative disorders (2001)
    Mark P. Mattson, Simonetta Camandola Journal of Clinical Investigation
  18. Impact of intermittent fasting on health and disease processes (2016)
    Mark P. Mattson, Valter D. Longo et al. Ageing Research Reviews
  19. Mitochondrial Manganese Superoxide Dismutase Prevents Neural Apoptosis and Reduces Ischemic Brain Injury: Suppression of Peroxynitrite Production, Lipid Peroxidation, and Mitochondrial Dysfunction (1998)
    Jeffrey N. Keller, Mark S. Kindy et al. Journal of Neuroscience
  20. Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States (2018)
    Mark P. Mattson, Thiruma V. Arumugam Cell Metabolism
  21. Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease (2008)
    Ilya Bezprozvanny, Mark P. Mattson Trends in Neurosciences
  22. Estrogens Attenuate and Corticosterone Exacerbates Excitotoxicity, Oxidative Injury, and Amyloid β‐Peptide Toxicity in Hippocampal Neurons (1996)
    Yadong Goodman, Annadora J. Bruce et al. Journal of Neurochemistry
  23. Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders (2003)
    Mark P. Mattson, Thomas B. Shea Trends in Neurosciences
  24. Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer’s disease model (2019)
    Peisu Zhang, Yuki Kishimoto et al. Nature Neuroscience
  25. Cellular Stress Responses, The Hormesis Paradigm, and Vitagenes: Novel Targets for Therapeutic Intervention in Neurodegenerative Disorders (2010)
    Vittorio Calabrese, Carolin Cornelius et al. Antioxidants and Redox Signaling
  26. Homocysteine Elicits a DNA Damage Response in Neurons That Promotes Apoptosis and Hypersensitivity to Excitotoxicity (2000)
    Inna I. Kruman, Carsten Culmsee et al. Journal of Neuroscience
  27. Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein (1993)
    Mark P. Mattson, Bin Cheng et al. Neuron
  28. A Role for 4‐Hydroxynonenal, an Aldehydic Product of Lipid Peroxidation, in Disruption of Ion Homeostasis and Neuronal Death Induced by Amyloid β‐Peptide (1997)
    Robert J. Mark, Mark A. Lovell et al. Journal of Neurochemistry
  29. Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits (2007)
    Sung‐Chun Tang, Thiruma V. Arumugam et al. Proceedings of the National Academy of Sciences
  30. Evidence that 4-Hydroxynonenal Mediates Oxidative Stress-Induced Neuronal Apoptosis (1997)
    Inna I. Kruman, Annadora J. Bruce‐Keller et al. Journal of Neuroscience
  31. Mitophagy and Alzheimer’s Disease: Cellular and Molecular Mechanisms (2017)
    Bryan A. Adriaanse, Nigel H. Greig et al. Trends in Neurosciences
  32. Diet‐induced insulin resistance impairs hippocampal synaptic plasticity and cognition in middle‐aged rats (2008)
    Alexis M. Stranahan, Eric D. Norman et al. Hippocampus
  33. Calcium and neurodegeneration (2007)
    Mark P. Mattson Aging Cell
  34. Superoxide Flashes in Single Mitochondria (2008)
    Wang Wang, Huaqiang Fang et al. Cell
  35. The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women (2010)
    Michelle Harvie, Mary Pegington et al. International Journal of Obesity
  36. Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake (2003)
    R. Michael Anson, Zhihong Guo et al. Proceedings of the National Academy of Sciences
  37. Neurotrophic Factors Attenuate Glutamate‐Induced Accumulation of Peroxides, Elevation of Intracellular Ca2+ Concentration, and Neurotoxicity and Increase Antioxidant Enzyme Activities in Hippocampal Neurons (1995)
    Mark P. Mattson, Mark A. Lovell et al. Journal of Neurochemistry
  38. Folic Acid Deficiency and Homocysteine Impair DNA Repair in Hippocampal Neurons and Sensitize Them to Amyloid Toxicity in Experimental Models of Alzheimer's Disease (2002)
    Inna I. Kruman, T. S. Kumaravel et al. Journal of Neuroscience
  39. Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation. (1995)
    Steven W. Barger, Koichi Furukawa et al. Proceedings of the National Academy of Sciences
  40. Calcium regulation of the neuronal growth cone (1988)
    Stanley B. Kater, Mark P. Mattson et al. Trends in Neurosciences
  41. An Overview of APP Processing Enzymes and Products (2009)
    Mark P. Mattson, Philip C. Wong et al. NeuroMolecular Medicine
  42. GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism (2009)
    Yazhou Li, Mark S. Kindy et al. Proceedings of the National Academy of Sciences
  43. NAD+ in Brain Aging and Neurodegenerative Disorders (2019)
    Sofie Lautrup, David Sinclair et al. Cell Metabolism
  44. Flipping the Metabolic Switch: Understanding and Applying the Health Benefits of Fasting (2017)
    Stephen D. Anton, Keelin Moehl et al. Obesity
  45. Brain metabolism in health, aging, and neurodegeneration (2017)
    Simonetta Camandola, Mark P. Mattson The EMBO Journal
  46. BDNF mediates adaptive brain and body responses to energetic challenges (2013)
    Krisztina Marosi, Mark P. Mattson Trends in Endocrinology and Metabolism
  47. Intermittent metabolic switching, neuroplasticity and brain health (2018)
    Mark P. Mattson, Keelin Moehl et al. Nature reviews. Neuroscience
  48. How does hormesis impact biology, toxicology, and medicine? (2017)
    Edward J. Calabrese, Mark P. Mattson SHILAP Revista de lepidopterología
  49. NAD + supplementation reduces neuroinflammation and cell senescence in a transgenic mouse model of Alzheimer’s disease via cGAS–STING (2021)
    Yujun Hou, Yong Wei et al. Proceedings of the National Academy of Sciences
  50. NAD + supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency (2018)
    Yujun Hou, Sofie Lautrup et al. Proceedings of the National Academy of Sciences
  51. Intermittent and periodic fasting, longevity and disease (2021)
    Valter D. Longo, Maira Di Tano et al. Nature Aging
  52. A Dynamical Systems View of Psychiatric Disorders—Practical Implications (2024)
    Marten Scheffer, Claudi Bockting et al. JAMA Psychiatry

Immediate Impact

5 by Nobel laureates 56 from Science/Nature 128 standout
Sub-graph 1 of 16

Citing Papers

The central role of DNA damage in the ageing process
2021 StandoutNature
From discoveries in ageing research to therapeutics for healthy ageing
2019 StandoutNature
34 intermediate papers

Works of Mark P. Mattson being referenced

Fasting: Molecular Mechanisms and Clinical Applications
2014 Standout
Anti-apoptotic Role of Telomerase in Pheochromocytoma Cells
1999
and 45 more

Author Peers

Author Last Decade Papers Cites
Mark P. Mattson 50681 51943 28661 948 125.5k
David M. Holtzman 26534 52505 15289 574 96.4k
Eliezer Masliah 33703 46485 29175 841 103.4k
Bradley T. Hyman 31994 59624 22824 723 111.3k
Kaj Blennow 32614 64391 12959 2.0k 118.7k
Carl W. Cotman 27855 25650 33526 659 76.2k
John Q. Trojanowski 45584 68747 31420 1.1k 148.3k
Solomon H. Snyder 73879 29487 57757 976 140.4k
Dennis J. Selkoe 48869 83348 23879 475 113.9k
Henrik Zetterberg 25444 45261 10397 1.9k 92.3k
Paul Greengard 69535 19363 51642 956 111.1k

All Works

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