Standout Papers

Progress and problems with the use of viral vectors for gene therapy 2000 2026 2008 2017 1.9k
  1. Progress and problems with the use of viral vectors for gene therapy (2003)
    Clare E. Thomas, Anja Ehrhardt et al. Nature Reviews Genetics
  2. Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways (2006)
    Dirk Grimm, Konrad L. Streetz et al. Nature
  3. Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics (2001)
    Mark A. Kay, Joseph C. Glorioso et al. Nature Medicine
  4. RNA interference in adult mice (2002)
    Anton P. McCaffrey, Leonard Meuse et al. Nature
  5. Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector (2000)
    Mark A. Kay, Catherine S. Manno et al. Nature Genetics
  6. Robust expansion of human hepatocytes in Fah−/−/Rag2−/−/Il2rg−/− mice (2007)
    Hisaya Azuma, Nicole K. Paulk et al. Nature Biotechnology
  7. AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B (2003)
    Catherine S. Manno, S Hutchison et al. Blood
  8. Human tRNA-derived small RNAs in the global regulation of RNA silencing (2010)
    Dirk Haussecker, Yong Huang et al. RNA
  9. A nonviral minicircle vector for deriving human iPS cells (2010)
    Fangjun Jia, Kitchener D. Wilson et al. Nature Methods
  10. In Vitro and In Vivo Gene Therapy Vector Evolution via Multispecies Interbreeding and Retargeting of Adeno-Associated Viruses (2008)
    Dirk Grimm, Joyce Lee et al. Journal of Virology
  11. State-of-the-art gene-based therapies: the road ahead (2011)
    Mark A. Kay Nature Reviews Genetics
  12. Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors (1997)
    Richard O. Snyder, Carol H. Miao et al. Nature Genetics
  13. A transfer-RNA-derived small RNA regulates ribosome biogenesis (2017)
    Hak Kyun Kim, Gabriele Fuchs et al. Nature
  14. Evaluating the state of the science for adeno-associated virus integration: An integrated perspective (2022)
    Denise E. Sabatino, Frederic D. Bushman et al. Molecular Therapy

Immediate Impact

13 by Nobel laureates 47 from Science/Nature 118 standout
Sub-graph 1 of 17

Citing Papers

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1 intermediate paper

Works of Mark A. Kay being referenced

Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals
2020
In Vitro and In Vivo Gene Therapy Vector Evolution via Multispecies Interbreeding and Retargeting of Adeno-Associated Viruses
2008 Standout

Author Peers

Author Last Decade Papers Cites
Mark A. Kay 25225 17120 2729 4329 293 32.9k
Luigi Naldini 28725 17183 2587 8958 306 43.0k
Didier Trono 24088 12601 6265 3137 281 38.5k
Richard C. Mulligan 22975 11860 1437 8500 200 40.8k
Frank L. Graham 17605 14251 3207 6361 184 28.5k
Daniel B. Rifkin 17199 5274 568 4090 227 32.0k
A. Dusty Miller 16813 14711 2234 4340 264 26.9k
Beverly L. Davidson 18942 8362 1293 1483 329 27.7k
Guangping Gao 16169 14196 3177 3461 349 23.9k
David T. Curiel 17513 17109 2682 10888 589 28.1k
Jeffrey D. Esko 17406 3307 1151 1544 300 28.9k

All Works

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2026