Standout Papers
- TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival (2003)
- TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling (2002)
- Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling (2003)
- TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth (2006)
- Dysregulation of the TSC-mTOR pathway in human disease (2004)
- AMPK and mTOR in Cellular Energy Homeostasis and Drug Targets (2011)
- ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS (2010)
- Spatial Coupling of mTOR and Autophagy Augments Secretory Phenotypes (2011)
- mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice (2011)
Immediate Impact
23 by Nobel laureates 34 from Science/Nature 315 standout
Citing Papers
mTOR substrate phosphorylation in growth control
2022 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
Works of Ken Inoki being referenced
Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling
2008
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
2002 Standout
Author Peers
| Author | Last Decade | Papers | Cites | ||||
|---|---|---|---|---|---|---|---|
| Ken Inoki | 12719 | 2973 | 2356 | 3364 | 92 | 17.6k | |
| Mathieu Laplante | 8725 | 3695 | 1576 | 3242 | 77 | 14.8k | |
| Roberto Zoncu | 12412 | 2603 | 4786 | 4762 | 71 | 19.6k | |
| George Thomas | 18168 | 3241 | 2848 | 1911 | 161 | 24.1k | |
| Sara C. Kozma | 11832 | 2215 | 1651 | 1477 | 97 | 16.3k | |
| Orian S. Shirihai | 10942 | 3769 | 1451 | 4289 | 158 | 16.3k | |
| Ruth T. Yu | 9907 | 5203 | 1039 | 2468 | 105 | 17.4k | |
| Dos D. Sarbassov | 12689 | 1565 | 1854 | 1626 | 48 | 15.9k | |
| Michael W. McBurney | 10393 | 4538 | 977 | 3135 | 157 | 19.2k | |
| Jorge Moscat | 12618 | 1405 | 2746 | 4198 | 181 | 18.1k | |
| Gerald W. Dorn | 13689 | 1913 | 1473 | 2227 | 183 | 19.0k |
All Works
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