Standout Papers

Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pat... 1991 2026 2002 2014 2.8k
  1. Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation (2001)
    John Kyriakis, Joseph Avruch Physiological Reviews
  2. The stress-activated protein kinase subfamily of c-Jun kinases (1994)
    John Kyriakis, Papia T. Banerjee et al. Nature
  3. Raptor, a Binding Partner of Target of Rapamycin (TOR), Mediates TOR Action (2002)
    Kenta Hara, Samuel Long et al. Cell
  4. Phosphorylation of c-jun mediated by MAP kinases (1991)
    Bernd Pulverer, John Kyriakis et al. Nature
  5. Mammalian MAPK Signal Transduction Pathways Activated by Stress and Inflammation: A 10-Year Update (2012)
    John Kyriakis, Joseph Avruch Physiological Reviews
  6. Raf-1 activates MAP kinase-kinase (1992)
    John Kyriakis, Harald App et al. Nature
  7. Amino Acid Sufficiency and mTOR Regulate p70 S6 Kinase and eIF-4E BP1 through a Common Effector Mechanism (1998)
    Kenta Hara, Kazuyoshi Yonezawa et al. Journal of Biological Chemistry
  8. Sounding the Alarm: Protein Kinase Cascades Activated by Stress and Inflammation (1996)
    John Kyriakis, Joseph Avruch Journal of Biological Chemistry
  9. Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun (1994)
    Irma Sánchez, Bruce J. Mayer et al. Nature
  10. Yap1 Acts Downstream of α-Catenin to Control Epidermal Proliferation (2011)
    Karin Schlegelmilch, Morvarid Mohseni et al. Cell
  11. Preparation and properties of plasma membrane and endoplasmic reticulum fragments from isolated rat fat cells (1971)
    Joseph Avruch, Donald F. Hoelzl Wallach Biochimica et Biophysica Acta (BBA) - Biomembranes
  12. Rheb Binds and Regulates the mTOR Kinase (2005)
    Samuel Long, Yenshou Lin et al. Current Biology
  13. Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1 (1993)
    Xianfeng Zhang, Jeffrey Settleman et al. Nature
  14. Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene (2009)
    Dawang Zhou, Claudius Conrad et al. Cancer Cell
  15. Protein kinase cascades activated by stress and inflammatory cytokines (1996)
    John Kyriakis, Joseph Avruch BioEssays
  16. Rapamycin-Induced Inhibition of the 70-Kilodalton S6 Protein Kinase (1992)
    Daniel J. Price, Jeffrey Grove et al. Science
  17. The Mammalian Target of Rapamycin (mTOR) Partner, Raptor, Binds the mTOR Substrates p70 S6 Kinase and 4E-BP1 through Their TOR Signaling (TOS) Motif (2003)
    Chiharu Tokunaga, Satoshi Eguchi et al. Journal of Biological Chemistry
  18. Raf meets Ras: completing the framework of a signal transduction pathway (1994)
    Joseph Avruch, Xianfeng Zhang et al. Trends in Biochemical Sciences

Immediate Impact

24 by Nobel laureates 135 from Science/Nature 310 standout
Sub-graph 1 of 15

Citing Papers

NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
2016 StandoutNature
A unifying model for mTORC1-mediated regulation of mRNA translation
2012 StandoutNature
14 intermediate papers

Works of Joseph Avruch being referenced

The TSC-mTOR Pathway Mediates Translational Activation of TOP mRNAs by Insulin Largely in a Raptor- or Rictor-Independent Manner
2008
TOR Deficiency in C. elegans Causes Developmental Arrest and Intestinal Atrophy by Inhibition of mRNA Translation
2002
and 21 more

Author Peers

Author Last Decade Papers Cites
Joseph Avruch 28923 8522 2403 4484 188 37.8k
Brian A. Hemmings 32877 7109 2353 5076 312 42.0k
Melanie H. Cobb 27094 5635 2294 5518 278 36.7k
Peter J. Parker 25180 7559 1511 3933 401 33.5k
Timothy Hla 23450 6728 2265 2691 244 34.9k
Michael N. Hall 33837 6600 2364 3034 241 44.2k
Sue Goo Rhee 30699 5249 1682 2535 243 40.9k
Hidenori Ichijo 20106 4517 1521 2699 283 29.5k
Dafna Bar‐Sagi 21859 5560 1513 9036 185 30.2k
Gary Bokoch 20320 10481 1109 3484 220 31.0k
John Blenis 38903 6295 2845 8109 221 51.3k

All Works

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