Standout Papers

T cell tolerance by clonal elimination in the thymus 1983 2026 1997 2011 1.8k
  1. T cell tolerance by clonal elimination in the thymus (1987)
    John W. Kappler, Neal W. Roehm et al. Cell
  2. Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity (1983)
    Deno P. Dialynas, D B Wilde et al. Immunological Reviews
  3. The Vβ-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice (1989)
    Janice White, Andrew Herman et al. Cell
  4. Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex (1988)
    John W. Kappler, Uwe D. Staerz et al. Nature
  5. Normal Development of Mice Deficient in β 2 M, MCClass I Proteins, and CD8 + T Cells (1990)
    Beverly H. Koller, Philippa Marrack et al. Science
  6. The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody. (1983)
    Kathryn Haskins, Ralph T. Kubo et al. The Journal of Experimental Medicine
  7. Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors. (1989)
    Ralph T. Kubo, Willi K. Born et al. The Journal of Immunology
  8. Control of Homeostasis of CD8 + Memory T Cells by Opposing Cytokines (2000)
    Chia‐Chi Ku, Masaaki Murakami et al. Science
  9. Type I Interferons Keep Activated T Cells Alive (1999)
    Philippa Marrack, John W. Kappler et al. The Journal of Experimental Medicine
  10. Antigen recognition by H-2-restricted T cells. I. Cell-free antigen processing. (1983)
    Richard Shimonkevitz, John W. Kappler et al. The Journal of Experimental Medicine
  11. Toll-like receptor 7 (TLR7)–driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity (2011)
    Anatoly V. Rubtsov, Kira Rubtsova et al. Blood
  12. Evidence for the Effects of a Superantigen in Rheumatoid Arthritis (1991)
    Xavier Paliard, Sterling G. West et al. Science
  13. An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder (2004)
    Michael B. Jordan, David A. Hildeman et al. Blood
  14. Superantigens and Their Potential Role in Human Disease (1993)
    Brian L. Kotzin, Donald Y.M. Leung et al. Advances in immunology
  15. Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen (1987)
    Denise Gay, Paul J. Maddon et al. Nature

Immediate Impact

40 by Nobel laureates 183 from Science/Nature 149 standout
Sub-graph 1 of 15

Citing Papers

Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Inflammasomes in health and disease
2012 StandoutNature

Works of John W. Kappler being referenced

Alum Induces Innate Immune Responses through Macrophage and Mast Cell Sensors, But These Sensors Are Not Required for Alum to Act As an Adjuvant for Specific Immunity
2009
Yeast surface display of a noncovalent MHC class II heterodimer complexed with antigenic peptide
2005

Author Peers

Author Last Decade Papers Cites
John W. Kappler 32313 6891 8215 372 42.0k
Philippa Marrack 39681 8497 9715 425 51.3k
Emil R. Unanue 24387 4877 10161 429 39.4k
Charles A. Janeway 39308 4377 11187 401 54.3k
Ethan M. Shevach 37250 3467 6521 421 47.2k
Herman Waldmann 22115 6275 6761 537 36.1k
Thomas A. Waldmann 27606 6624 10284 573 47.0k
Max D. Cooper 23194 5608 6914 442 33.1k
Andreas Radbruch 18832 4117 6712 437 30.3k
William E. Paul 30017 3353 8087 343 42.0k
Bernard Malissen 26910 2729 7514 398 34.9k

All Works

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2026