Standout Papers

A general framework for estimating the relative pathogenicity of... 2008 2026 2014 2020 3.5k
  1. A general framework for estimating the relative pathogenicity of human genetic variants (2014)
    Martin Kircher, Daniela Witten et al. Nature Genetics
  2. Next-generation DNA sequencing (2008)
    Jay Shendure, Hanlee P. Ji Nature Biotechnology
  3. The single-cell transcriptional landscape of mammalian organogenesis (2019)
    Junyue Cao, Malte Spielmann et al. Nature
  4. CADD: predicting the deleteriousness of variants throughout the human genome (2018)
    Philipp Rentzsch, Daniela Witten et al. Nucleic Acids Research
  5. Targeted capture and massively parallel sequencing of 12 human exomes (2009)
    Sarah Ng, Emily H. Turner et al. Nature
  6. Exome sequencing identifies the cause of a mendelian disorder (2009)
    Sarah Ng, Kati J. Buckingham et al. Nature Genetics
  7. Exome sequencing as a tool for Mendelian disease gene discovery (2011)
    Michael J. Bamshad, Sarah Ng et al. Nature Reviews Genetics
  8. Chromosome-scale scaffolding of de novo genome assemblies based on chromatin interactions (2013)
    Joshua N. Burton, Andrew C. Adey et al. Nature Biotechnology
  9. Cell-free DNA Comprises an In Vivo Nucleosome Footprint that Informs Its Tissues-Of-Origin (2016)
    Matthew W. Snyder, Martin Kircher et al. Cell
  10. Comprehensive single-cell transcriptional profiling of a multicellular organism (2017)
    Junyue Cao, Jonathan S. Packer et al. Science
  11. Accurate Multiplex Polony Sequencing of an Evolved Bacterial Genome (2005)
    Jay Shendure, Gregory J. Porreca et al. Science
  12. Target-enrichment strategies for next-generation sequencing (2010)
    Lira Mamanova, Alison J. Coffey et al. Nature Methods
  13. Multiplex single-cell profiling of chromatin accessibility by combinatorial cellular indexing (2015)
    Darren A. Cusanovich, Riza M. Daza et al. Science
  14. Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations (2011)
    Brian J. O’Roak, Pelagia Deriziotis et al. Nature Genetics
  15. A three-dimensional model of the yeast genome (2010)
    Zhijun Duan, Mirela Andronescu et al. Nature
  16. Analysis of Genetic Inheritance in a Family Quartet by Whole-Genome Sequencing (2010)
    Jared C. Roach, Gustavo Glusman et al. Science
  17. Classification and characterization of microsatellite instability across 18 cancer types (2016)
    Ronald J. Hause, Colin C. Pritchard et al. Nature Medicine
  18. Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants (2012)
    Wenqing Fu, Timothy D. O’Connor et al. Nature
  19. DNA sequencing at 40: past, present and future (2017)
    Jay Shendure, Shankar Balasubramanian et al. Nature
  20. Joint profiling of chromatin accessibility and gene expression in thousands of single cells (2018)
    Junyue Cao, Darren A. Cusanovich et al. Science
  21. Whole-organism lineage tracing by combinatorial and cumulative genome editing (2016)
    Aaron McKenna, Gregory M. Findlay et al. Science
  22. Fragment Length of Circulating Tumor DNA (2016)
    Hunter R. Underhill, Jacob O. Kitzman et al. PLoS Genetics
  23. Accurate classification of BRCA1 variants with saturation genome editing (2018)
    Gregory M. Findlay, Riza M. Daza et al. Nature
  24. A Single-Cell Atlas of In Vivo Mammalian Chromatin Accessibility (2018)
    Darren A. Cusanovich, Andrew J. Hill et al. Cell
  25. The 4D nucleome project (2017)
    Job Dekker, Andrew S. Belmont et al. Nature
  26. Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain (2018)
    Bushra Raj, Daniel E. Wagner et al. Nature Biotechnology
  27. Cicero Predicts cis-Regulatory DNA Interactions from Single-Cell Chromatin Accessibility Data (2018)
    Hannah A. Pliner, Jonathan S. Packer et al. Molecular Cell
  28. A human cell atlas of fetal gene expression (2020)
    Junyue Cao, Diana R. O’Day et al. Science
  29. A Genome-wide Framework for Mapping Gene Regulation via Cellular Genetic Screens (2019)
    Molly Gasperini, Andrew J. Hill et al. Cell
  30. A brief history of human disease genetics (2020)
    Melina Claussnitzer, Judy H. Cho et al. Nature
  31. CADD-Splice—improving genome-wide variant effect prediction using deep learning-derived splice scores (2021)
    Philipp Rentzsch, Max Schubach et al. Genome Medicine
  32. High-content CRISPR screening (2022)
    Christoph Bock, Paul Datlinger et al. Nature Reviews Methods Primers
  33. Single-cell lineage tracing of metastatic cancer reveals selection of hybrid EMT states (2021)
    Kamen P. Simeonov, China N. Byrns et al. Cancer Cell
  34. Precise genomic deletions using paired prime editing (2021)
    Junhong Choi, Wei Chen et al. Nature Biotechnology
  35. High-content CRISPR screening (2022)
    Christoph Bock, Paul Datlinger et al. Nature Reviews Methods Primers
  36. Embryo model completes gastrulation to neurulation and organogenesis (2022)
    Gianluca Amadei, Charlotte E. Handford et al. Nature
  37. Pluripotent stem cell-derived model of the post-implantation human embryo (2023)
    Bailey A. T. Weatherbee, Carlos W. Gantner et al. Nature

Immediate Impact

7 by Nobel laureates 56 from Science/Nature 112 standout
Sub-graph 1 of 17

Citing Papers

Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Mechanical regulation of glycolysis via cytoskeleton architecture
2020 StandoutNature
38 intermediate papers

Works of Jay Shendure being referenced

Accurate classification of BRCA1 variants with saturation genome editing
2018 StandoutNature
A general framework for estimating the relative pathogenicity of human genetic variants
2014 Standout
and 23 more

Author Peers

Author Last Decade Papers Cites
Jay Shendure 34896 16658 8042 295 50.4k
Andrew P. Feinberg 44543 15391 6693 233 61.5k
R Myers 32120 12552 4268 297 49.2k
Rafael A. Irizarry 37896 7974 7932 181 55.5k
David Altshuler 29072 29936 6982 148 62.4k
Steve Horvath 42656 10762 8104 437 67.8k
Adrian Bird 50696 21326 4108 229 60.9k
Michael Wigler 34084 9063 5927 217 44.8k
Mark Gerstein 46809 8430 7660 543 59.7k
J. Michael Bishop 32788 11396 5067 356 48.3k
Mark D. Robinson 28590 5379 7249 164 45.5k

All Works

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