Standout Papers

A Toll-like receptor recognizes bacterial DNA 2000 2026 2008 2017 5.2k
  1. A Toll-like receptor recognizes bacterial DNA (2000)
    Hiroaki Hemmi, Osamu Takeuchi et al. Nature
  2. Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8 (2004)
    Florian Heil, Hiroaki Hemmi et al. Science
  3. Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition (2001)
    Stefan Bauer, Carsten J. Kirschning et al. Proceedings of the National Academy of Sciences
  4. Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6 (2005)
    Hans Häcker, Vanessa Redecke et al. Nature
  5. HSP70 as Endogenous Stimulus of the Toll/Interleukin-1 Receptor Signal Pathway (2002)
    R. Martin Vabulas, Parviz Ahmad‐Nejad et al. Journal of Biological Chemistry
  6. Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease (2007)
    Katharina Lahl, Christoph Loddenkemper et al. The Journal of Experimental Medicine
  7. Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells (1998)
    Tim Sparwasser, R. Martin Vabulas et al. European Journal of Immunology
  8. Endocytosed HSP60s Use Toll-like Receptor 2 (TLR2) and TLR4 to Activate the Toll/Interleukin-1 Receptor Signaling Pathway in Innate Immune Cells (2001)
    R. Martin Vabulas, Parviz Ahmad‐Nejad et al. Journal of Biological Chemistry
  9. Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments (2002)
    Parviz Ahmad‐Nejad, Hans Häcker et al. European Journal of Immunology
  10. CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation (1998)
    Hans Häcker, Harald Mischak et al. The EMBO Journal
  11. Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism (2001)
    Catherine Werts, Richard I. Tapping et al. Nature Immunology
  12. Cyclosporin A mediates immunosuppression of primary cytotoxic T cell responses by impairing the release of interleukin 1 and interleukin 2 (1981)
    Donald Bunjes, Conny Hardt et al. European Journal of Immunology
  13. T cell-mediated lethal shock triggered in mice by the superantigen staphylococcal enterotoxin B: critical role of tumor necrosis factor. (1992)
    Thomas Miethke, Claudia Wahl et al. The Journal of Experimental Medicine

Immediate Impact

33 by Nobel laureates 71 from Science/Nature 180 standout
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Citing Papers

A T-bet gradient controls the fate and function of CCR6−RORγt+ innate lymphoid cells
2013 StandoutNature
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
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Works of Hermann Wagner being referenced

Maternal TLR signaling is required for prenatal asthma protection by the nonpathogenic microbe Acinetobacter lwoffii F78
2009
A Toll-like receptor recognizes bacterial DNA
2000 StandoutNature

Author Peers

Author Last Decade Papers Cites
Hermann Wagner 31027 10157 6968 414 41.7k
Charles A. Janeway 39308 11187 5560 401 54.3k
Satoshi Uematsu 23442 10981 6854 215 36.8k
Alan Aderem 19662 15237 6288 216 38.3k
Tsuneyasu Kaisho 29884 9411 6032 163 39.7k
Douglas T. Golenbock 30420 14972 10569 287 50.3k
John D. Lambris 26886 9680 5409 568 46.7k
Jay K. Kolls 21309 8340 8319 467 40.1k
Bruce Beutler 37780 17041 10744 401 63.8k
Masahiro Yamamoto 19826 9990 5693 269 29.2k
Volker Brinkmann 22764 19129 5075 248 44.5k

All Works

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2026