Standout Papers

Inflammasome-activated gasdermin D causes pyroptosis by form... 2010 2026 2015 2020 2.3k
  1. Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores (2016)
    Xing Liu, Zhibin Zhang et al. Nature
  2. Gasdermin E suppresses tumour growth by activating anti-tumour immunity (2020)
    Zhibin Zhang, Ying Zhang et al. Nature
  3. Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes (2014)
    Alvin Lu, Venkat Giri Magupalli et al. Cell
  4. The RIP1/RIP3 Necrosome Forms a Functional Amyloid Signaling Complex Required for Programmed Necrosis (2012)
    Jixi Li, Thomas J. McQuade et al. Cell
  5. Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling (2010)
    Su‐Chang Lin, Hao Wu et al. Nature
  6. The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages (2017)
    Charles L. Evavold, Jianbin Ruan et al. Immunity
  7. Pathogen blockade of TAK1 triggers caspase-8–dependent cleavage of gasdermin D and cell death (2018)
    Pontus Ørning, Dan Weng et al. Science
  8. Molecular Basis of NF-κB Signaling (2013)
    Johanna Napetschnig, Hao Wu Annual Review of Biophysics
  9. FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation (2020)
    Jun Hu, Xing Liu et al. Nature Immunology
  10. Structural Mechanisms of NLRP3 Inflammasome Assembly and Activation (2023)
    Jianing Fu, Hao Wu Annual Review of Immunology
  11. Distinct molecular mechanism for initiating TRAF6 signalling (2002)
    Hong Ye, Joseph R. Arron et al. Nature
  12. Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome (2019)
    Humayun Sharif, Li Wang et al. Nature
  13. All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction (2002)
    Jee Young Chung, Young Chul Park et al. Journal of Cell Science
  14. Channelling inflammation: gasdermins in physiology and disease (2021)
    Xing Liu, Shiyu Xia et al. Nature Reviews Drug Discovery
  15. An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells (2016)
    Ivan Zanoni, Yunhao Tan et al. Science
  16. Gasdermin D pore structure reveals preferential release of mature interleukin-1 (2021)
    Shiyu Xia, Zhibin Zhang et al. Nature
  17. An Acetylation Switch of the NLRP3 Inflammasome Regulates Aging-Associated Chronic Inflammation and Insulin Resistance (2020)
    Ming He, Hou-Hsien Chiang et al. Cell Metabolism
  18. HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation (2020)
    Venkat Giri Magupalli, Roberto Negro et al. Science
  19. Inflammasome activation at the crux of severe COVID-19 (2021)
    Setu M. Vora, Judy Lieberman et al. Nature reviews. Immunology
  20. NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation (2021)
    Liudmila Andreeva, Liron David et al. Cell
  21. Cryo-EM structures of the active NLRP3 inflammasome disc (2022)
    Le Xiao, Venkat Giri Magupalli et al. Nature
  22. The NK cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells (2023)
    Sumit Sen Santara, Dian-Jang Lee et al. Nature
  23. Mechanistic insights from inflammasome structures (2024)
    Jianing Fu, Kate Schroder et al. Nature reviews. Immunology
  24. NINJ1 mediates plasma membrane rupture by cutting and releasing membrane disks (2024)
    Liron David, Louis Hollingsworth et al. Cell

Immediate Impact

2 by Nobel laureates 45 from Science/Nature 108 standout
Sub-graph 1 of 18

Citing Papers

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31 intermediate papers

Works of Hao Wu being referenced

The NK cell receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells
2023 StandoutNature
An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells
2016 StandoutScience
and 22 more

Author Peers

Author Last Decade Papers Cites
Hao Wu 19583 10815 3618 259 27.0k
Feng Shao 22926 10345 1690 162 30.6k
Niels Borregaard 10091 13235 2230 253 29.5k
Emad S. Alnemri 32380 12238 3692 164 41.4k
Veit Hornung 22726 24034 2232 199 38.6k
Kenneth L. Rock 17348 18653 1636 202 33.4k
Vikas P. Sukhatme 16498 5782 5972 248 32.3k
Nigel Mackman 12470 9698 5554 501 38.8k
Kate Schroder 14096 9654 1103 140 23.1k
Jiahuai Han 29478 10897 6601 319 43.3k
Marco E. Bianchi 12993 11477 1959 224 30.5k

All Works

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2026