Standout Papers

Apolipoprotein E: high-avidity binding to beta-amyloid and increased fr... 1983 2026 1997 2011 3.3k
  1. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. (1993)
    Warren J. Strittmatter, Ann M. Saunders et al. Proceedings of the National Academy of Sciences
  2. Regulation of Cell Death Protease Caspase-9 by Phosphorylation (1998)
    Michael H. Cardone, Natalie Roy et al. Science
  3. Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase (1995)
    Muneesh Tewari, Long T. Quan et al. Cell
  4. Caspases: Intracellular Signaling by Proteolysis (1997)
    Guy S. Salvesen, Vishva M. Dixit Cell
  5. HUMAN PLASMA PROTEINASE INHIBITORS (1983)
    J. Travis, Guy S. Salvesen Annual Review of Biochemistry
  6. IAP proteins: blocking the road to death's door (2002)
    Guy S. Salvesen, Colin S. Duckett Nature Reviews Molecular Cell Biology
  7. Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease. (1993)
    Warren J. Strittmatter, Karl H. Weisgraber et al. Proceedings of the National Academy of Sciences
  8. Mechanisms of caspase activation (2003)
    Kelly M. Boatright, Guy S. Salvesen Current Opinion in Cell Biology
  9. The Serpins Are an Expanding Superfamily of Structurally Similar but Functionally Diverse Proteins (2001)
    Gary A. Silverman, Phillip I. Bird et al. Journal of Biological Chemistry
  10. Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis (2011)
    Andrew Oberst, Christopher P. Dillon et al. Nature
  11. Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis (2010)
    Faraaz B. Chekeni, Michael R. Elliott et al. Nature
  12. Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1β converting enzyme (1992)
    Caroline A. Ray, Roy A. Black et al. Cell
  13. The apoptosome: signalling platform of cell death (2007)
    Stefan J. Riedl, Guy S. Salvesen Nature Reviews Molecular Cell Biology
  14. An Induced Proximity Model for Caspase-8 Activation (1998)
    Marta Muzio, Brent R. Stockwell et al. Journal of Biological Chemistry
  15. A Unified Model for Apical Caspase Activation (2003)
    Kelly M. Boatright, Martin Renatus et al. Molecular Cell
  16. Caspase activation: The induced-proximity model (1999)
    Guy S. Salvesen, Vishva M. Dixit Proceedings of the National Academy of Sciences
  17. The protein structures that shape caspase activity, specificity, activation and inhibition (2004)
    Pablo Fuentes‐Prior, Guy S. Salvesen Biochemical Journal
  18. Pro-caspase-3 Is a Major Physiologic Target of Caspase-8 (1998)
    Henning R. Stennicke, Juliane M. Jürgensmeier et al. Journal of Biological Chemistry
  19. Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family (2006)
    Brendan P. Eckelman, Guy S. Salvesen et al. EMBO Reports
  20. Structural Basis for the Inhibition of Caspase-3 by XIAP (2001)
    Stefan J. Riedl, Martin Renatus et al. Cell
  21. Human Caspases: Activation, Specificity, and Regulation (2009)
    Cristina Pop, Guy S. Salvesen Journal of Biological Chemistry
  22. Lysosomal Protease Pathways to Apoptosis (2001)
    Veronika Stoka, Boris Turk et al. Journal of Biological Chemistry
  23. Caspase Cleavage of Keratin 18 and Reorganization of Intermediate Filaments during Epithelial Cell Apoptosis (1997)
    Carlos Caulı́n, Guy S. Salvesen et al. The Journal of Cell Biology
  24. A Single BIR Domain of XIAP Sufficient for Inhibiting Caspases (1998)
    Ryōsuke Takahashi, Quinn L. Deveraux et al. Journal of Biological Chemistry
  25. Isolation of six cysteine proteinase inhibitors from human urine. Their physicochemical and enzyme kinetic properties and concentrations in biological fluids. (1986)
    Magnus Abrahamson, A. John Barrett et al. Journal of Biological Chemistry

Immediate Impact

20 by Nobel laureates 119 from Science/Nature 295 standout
Sub-graph 1 of 15

Citing Papers

Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis
2019 StandoutNature
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
2015 StandoutNature
19 intermediate papers

Works of Guy S. Salvesen being referenced

Caspase Substrates and Inhibitors
2013
The apoptosome: signalling platform of cell death
2007 Standout
and 19 more

Author Peers

Author Last Decade Papers Cites
Guy S. Salvesen 36881 8899 8145 9492 293 54.0k
Hediye Erdjument‐Bromage 52815 7276 5909 6857 283 67.2k
John Blenis 38903 8109 5551 6419 221 51.3k
Paul Tempst 61550 8205 7571 8945 320 79.9k
Vamsi K. Mootha 50490 6842 11345 7137 197 70.9k
Xiaodong Wang 48200 7966 7429 11272 305 62.6k
Erwin F. Wagner 33303 14036 7924 7459 356 49.9k
Josef Penninger 40322 14525 7432 17755 578 76.7k
Dario R. Alessi 50134 7625 5602 4899 308 64.7k
Stanley J. Korsmeyer 59060 15203 7600 15078 230 83.2k
Gérard I. Evan 29571 11800 5517 5650 244 42.5k

All Works

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