Standout Papers

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabdi... 1993 2026 2004 2015 3.6k
  1. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans (2000)
    Brenda J. Reinhart, Frank J. Slack et al. Nature
  2. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans (1993)
    Bruce Wightman, Ilho Ha et al. Cell
  3. Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA (2000)
    Amy E. Pasquinelli, Brenda J. Reinhart et al. Nature
  4. daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans (1997)
    Koutarou D. Kimura, Heidi A. Tissenbaum et al. Science
  5. The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans (1997)
    Scott Ogg, Suzanne Paradis et al. Nature
  6. Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing (2001)
    Alla Grishok, Amy E. Pasquinelli et al. Cell
  7. A uniform system for microRNA annotation (2003)
    Victor Ambros, Bonnie Bartel et al. RNA
  8. Physical and genetic characterization of symbiotic and auxotrophic mutants of Rhizobium meliloti induced by transposon Tn5 mutagenesis (1982)
    Harry Meade, Sharon R. Long et al. Journal of Bacteriology
  9. Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes (2003)
    Kaveh Ashrafi, Jennifer L. Watts et al. Nature
  10. A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity (2002)
    Siu Sylvia Lee, Raymond Lee et al. Nature Genetics
  11. A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans (1996)
    Jason Z Morris, Heidi A. Tissenbaum et al. Nature
  12. The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. (1988)
    Winship Herr, Richard A. Sturm et al. Genes & Development
  13. The lin-41 RBCC Gene Acts in the C. elegans Heterochronic Pathway between the let-7 Regulatory RNA and the LIN-29 Transcription Factor (2000)
    Frank J. Slack, Michael Basson et al. Molecular Cell
  14. A general method for site-directed mutagenesis in prokaryotes (1981)
    Gary Ruvkun, Frederick M. Ausubel Nature
  15. Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor (1998)
    Suzanne Paradis, Gary Ruvkun Genes & Development
  16. DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism (2003)
    Siu Sylvia Lee, Scott Kennedy et al. Science
  17. The unc-86 gene product couples cell lineage and cell identity in C. elegans (1990)
    Michael Finney, Gary Ruvkun Cell
  18. Regulation of C. elegans Life-Span by Insulinlike Signaling in the Nervous System (2000)
    Catherine A. Wolkow, Koutarou D. Kimura et al. Science
  19. Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant (2000)
    Ji Ying Sze, Martin Victor et al. Nature
  20. Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family (2001)
    Sarah B. Pierce, Michael A. Costa et al. Genes & Development
  21. High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis (2013)
    Schraga Schwartz, Sudeep D. Agarwala et al. Cell
  22. Identification of many microRNAs that copurify with polyribosomes in mammalian neurons (2003)
    John Kim, Anna M. Krichevsky et al. Proceedings of the National Academy of Sciences
  23. A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans (2004)
    Scott Kennedy, Duo Wang et al. Nature
  24. C. elegans Major Fats Are Stored in Vesicles Distinct from Lysosome-Related Organelles (2009)
    Eyleen J. O’Rourke, Alexander A. Soukas et al. Cell Metabolism
  25. Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans (2009)
    Alexander A. Soukas, Elizabeth A. Kane et al. Genes & Development
  26. The C. elegans cell lineage and differentiation gene unc-86 encodes a protein with a homeodomain and extended similarity to transcription factors (1988)
    Michael Finney, Gary Ruvkun et al. Cell
  27. Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses (2012)
    Justine A. Melo, Gary Ruvkun Cell
  28. Caenorhabditis elegans responses to bacteria from its natural habitats (2016)
    Buck S. Samuel, Christian Braendle et al. Proceedings of the National Academy of Sciences
  29. MXL-3 and HLH-30 transcriptionally link lipolysis and autophagy to nutrient availability (2013)
    Eyleen J. O’Rourke, Gary Ruvkun Nature Cell Biology
  30. Interspecies homology of nitrogenase genes. (1980)
    Gary Ruvkun, Frederick M. Ausubel Proceedings of the National Academy of Sciences
  31. Caenorhabditis elegans pathways that surveil and defend mitochondria (2014)
    Ying Liu, Buck S. Samuel et al. Nature

Immediate Impact

59 by Nobel laureates 105 from Science/Nature 263 standout
Sub-graph 1 of 13

Citing Papers

Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions
2015 StandoutNature
11 intermediate papers

Works of Gary Ruvkun being referenced

Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019
High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis
2013 Standout
and 2 more

Author Peers

Author Last Decade Papers Cites
Gary Ruvkun 17282 26502 6093 10786 211 42.0k
H. Robert Horvitz 20889 31306 8183 12414 249 50.8k
Leonard Guarente 9064 28560 3399 4006 204 54.1k
Ronald H.A. Plasterk 5268 23453 1311 8873 192 31.2k
Victor Ambros 6034 31353 1444 24890 107 41.4k
Jan H.J. Hoeijmakers 2581 37648 2115 8279 394 47.2k
Marı́a A. Blasco 8108 28481 1324 3549 286 47.8k
John B. Hogenesch 3523 12981 14817 3045 171 32.7k
Paolo Sassone‐Corsi 4015 23198 14182 2419 425 47.4k
Anne Brunet 5582 26195 1254 3778 143 37.9k
Kunihiro Matsumoto 3292 19956 1185 5372 232 28.9k

All Works

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