Standout Papers

A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy 1998 2026 2007 2016 2.1k
  1. A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy (1998)
    Jeffery D. Molkentin, Jianrong Lu et al. Cell
  2. Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres (2002)
    Jiandie D. Lin, Haiyan Wu et al. Nature
  3. The many roles of histone deacetylases in development and physiology: implications for disease and therapy (2008)
    Michael Haberland, Rusty L. Montgomery et al. Nature Reviews Genetics
  4. Transient Regenerative Potential of the Neonatal Mouse Heart (2011)
    Enzo R. Porrello, Ahmed I. Mahmoud et al. Science
  5. Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis (2008)
    Eva van Rooij, Lillian B. Sutherland et al. Proceedings of the National Academy of Sciences
  6. The Endothelial-Specific MicroRNA miR-126 Governs Vascular Integrity and Angiogenesis (2008)
    Shusheng Wang, Arin B. Aurora et al. Developmental Cell
  7. MicroRNAs in Stress Signaling and Human Disease (2012)
    Joshua T. Mendell, Eric N. Olson Cell
  8. Control of Stress-Dependent Cardiac Growth and Gene Expression by a MicroRNA (2007)
    Eva van Rooij, Lillian B. Sutherland et al. Science
  9. A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure (2006)
    Eva van Rooij, Lillian B. Sutherland et al. Proceedings of the National Academy of Sciences
  10. Cardiac Hypertrophy: The Good, the Bad, and the Ugly (2003)
    Norbert Frey, Eric N. Olson Annual Review of Physiology
  11. NFAT Signaling (2002)
    Gerald R. Crabtree, Eric N. Olson Cell
  12. Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene (1993)
    Paul Hasty, Allan Bradley et al. Nature
  13. Delivery of MicroRNA-126 by Apoptotic Bodies Induces CXCL12-Dependent Vascular Protection (2009)
    Alma Zernecke, Kiril Bidzhekov et al. Science Signaling
  14. Pervasive roles of microRNAs in cardiovascular biology (2011)
    Eric M. Small, Eric N. Olson Nature
  15. p53-Independent Expression of p21 Cip1 in Muscle and Other Terminally Differentiating Cells (1995)
    Susan B. Parker, Gregor Eichele et al. Science
  16. Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis. (1997)
    Jeffery D. Molkentin, Stephen A. Duncan et al. Genes & Development
  17. A Micropeptide Encoded by a Putative Long Noncoding RNA Regulates Muscle Performance (2015)
    Douglas M. Anderson, K.M. Anderson et al. Cell
  18. Heart repair by reprogramming non-myocytes with cardiac transcription factors (2012)
    Kunhua Song, Young-Jae Nam et al. Nature
  19. TRANSCRIPTIONAL CONTROL OF MUSCLE DEVELOPMENT BY MYOCYTE ENHANCER FACTOR-2 (MEF2) PROTEINS (1998)
    Brian L. Black, Eric N. Olson Annual Review of Cell and Developmental Biology
  20. Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation (2000)
    Timothy A. McKinsey, Chun‐Li Zhang et al. Nature
  21. Control of Mouse Cardiac Morphogenesis and Myogenesis by Transcription Factor MEF2C (1997)
    Qing Lin, John J. Schwarz et al. Science
  22. A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type (1998)
    Eva R. Chin, Eric N. Olson et al. Genes & Development
  23. Glycogen synthase kinase-3β mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore (2004)
    Magdalena Juhaszova, Dmitry B. Zorov et al. Journal of Clinical Investigation
  24. Cardiac Plasticity (2008)
    Joseph A. Hill, Eric N. Olson New England Journal of Medicine
  25. The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche (2010)
    Fatih Kocabaş, Junke Zheng et al. Cell stem cell
  26. Expression of Cre recombinase in the developing mouse limb bud driven by a Prxl enhancer (2002)
    Malcolm Logan, James F. Martin et al. genesis
  27. Class II Histone Deacetylases Act as Signal-Responsive Repressors of Cardiac Hypertrophy (2002)
    Chun Li Zhang, Timothy A. McKinsey et al. Cell
  28. A Family of microRNAs Encoded by Myosin Genes Governs Myosin Expression and Muscle Performance (2009)
    Eva van Rooij, Daniel Quiat et al. Developmental Cell
  29. A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program. (1989)
    Diane G. Edmondson, Eric N. Olson Genes & Development
  30. Gene Regulatory Networks in the Evolution and Development of the Heart (2006)
    Eric N. Olson Science
  31. Linking actin dynamics and gene transcription to drive cellular motile functions (2010)
    Eric N. Olson, Alfred Nordheim Nature Reviews Molecular Cell Biology
  32. Deacetylase inhibition promotes the generation and function of regulatory T cells (2007)
    Ran Tao, Edwin F. de Zoeten et al. Nature Medicine
  33. Activation of Cardiac Gene Expression by Myocardin, a Transcriptional Cofactor for Serum Response Factor (2001)
    Da‐Zhi Wang, Priscilla S. Chang et al. Cell
  34. MyoD family: a paradigm for development? (1990)
    Eric N. Olson Genes & Development
  35. Analysis of the tendon cell fate using Scleraxis, a specific marker for tendons and ligaments (2001)
    Ronen Schweitzer, L. Charles Murtaugh et al. Development
  36. Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins (1995)
    Jeffery D. Molkentin, Brian L. Black et al. Cell
  37. Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy (2015)
    Chengzu Long, Leonela Amoasii et al. Science
  38. Hippo pathway effector Yap promotes cardiac regeneration (2013)
    Mei Xin, Yuri Kim et al. Proceedings of the National Academy of Sciences
  39. Hypertrophy of the Heart (2004)
    Norbert Frey, Hugo A. Katus et al. Circulation
  40. MEF2: a central regulator of diverse developmental programs (2007)
    Matthew J. Potthoff, Eric N. Olson Development
  41. Signaling Pathways in Skeletal Muscle Remodeling (2006)
    Rhonda Bassel‐Duby, Eric N. Olson Annual Review of Biochemistry
  42. microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart (2008)
    Ning Liu, Svetlana Bezprozvannaya et al. Genes & Development
  43. Histone Deacetylase 4 Controls Chondrocyte Hypertrophy during Skeletogenesis (2004)
    Rick B. Vega, Koichi Matsuda et al. Cell
  44. bHLH factors in muscle development: dead lines and commitments, what to leave in and what to leave out. (1994)
    Eric N. Olson, William H. Klein Genes & Development
  45. Macrophages are required for neonatal heart regeneration (2014)
    Arin B. Aurora, Enzo R. Porrello et al. Journal of Clinical Investigation
  46. MicroRNA-206 Delays ALS Progression and Promotes Regeneration of Neuromuscular Synapses in Mice (2009)
    Gregorio Valdez, Viviana Moresi et al. Science
  47. MEF2: a calcium-dependent regulator of cell division, differentiation and death (2002)
    Timothy A. McKinsey, Chun Li Zhang et al. Trends in Biochemical Sciences
  48. A peptide encoded by a transcript annotated as long noncoding RNA enhances SERCA activity in muscle (2016)
    Benjamin R. Nelson, Catherine A. Makarewich et al. Science
  49. Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility (2007)
    Rusty L. Montgomery, Christopher A. Davis et al. Genes & Development
  50. Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family (2012)
    Enzo R. Porrello, Ahmed I. Mahmoud et al. Proceedings of the National Academy of Sciences
  51. Prevention of muscular dystrophy in mice by CRISPR/Cas9–mediated editing of germline DNA (2014)
    Chengzu Long, John McAnally et al. Science
  52. IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1 (1999)
    Antonio Musarò, Karl J. A. McCullagh et al. Nature
  53. A new myocyte-specific enhancer-binding factor that recognizes a conserved element associated with multiple muscle-specific genes. (1989)
    Lani A. Gossett, David J. Kelvin et al. Molecular and Cellular Biology
  54. A Twist Code Determines the Onset of Osteoblast Differentiation (2004)
    Peter Bialek, Xiangli Yang et al. Developmental Cell
  55. Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND (1997)
    Deepak Srivastava, Qing Lin et al. Nature Genetics
  56. MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury (2009)
    Mei Xin, Eric M. Small et al. Genes & Development
  57. MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1 (2014)
    Andreas Schober, Maliheh Nazari-Jahantigh et al. Nature Medicine
  58. MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles (2012)
    Eva van Rooij, Eric N. Olson Nature Reviews Drug Discovery
  59. Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth (2003)
    Kai Yu, Jian Xu et al. Development
  60. Regulation of tendon differentiation by scleraxis distinguishes force-transmitting tendons from muscle-anchoring tendons (2007)
    David A. Conner, Douglas R. Keene et al. Development
  61. Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing (2020)
    Tuo Wei, Qiang Cheng et al. Nature Communications
  62. Myomaker is a membrane activator of myoblast fusion and muscle formation (2013)
    Douglas P. Millay, Jason ORourke et al. Nature
  63. Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy (2018)
    Leonela Amoasii, John Hildyard et al. Science
  64. Therapeutic approaches for cardiac regeneration and repair (2018)
    Hisayuki Hashimoto, Eric N. Olson et al. Nature Reviews Cardiology
  65. Precise correction of Duchenne muscular dystrophy exon deletion mutations by base and prime editing (2021)
    Francesco Chemello, Andreas C. Chai et al. Science Advances
  66. Base editing correction of hypertrophic cardiomyopathy in human cardiomyocytes and humanized mice (2023)
    Andreas C. Chai, Miao Cui et al. Nature Medicine

Immediate Impact

13 by Nobel laureates 60 from Science/Nature 122 standout
Sub-graph 1 of 21

Citing Papers

The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
9 intermediate papers

Works of Eric N. Olson being referenced

Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing
2018
CRISPR-Cpf1 correction of muscular dystrophy mutations in human cardiomyocytes and mice
2017
and 5 more

Author Peers

Author Last Decade Papers Cites
Eric N. Olson 107676 20406 15298 23802 753 133.2k
Nahum Sonenberg 75137 9874 8424 12574 664 94.7k
Peter Carmeliet 52350 5706 5286 27080 720 98.1k
George D. Yancopoulos 54500 6777 5959 11822 425 101.4k
Kari Alitalo 56192 3771 4349 12285 713 93.0k
James A. Richardson 35563 7660 6106 8740 356 56.8k
Gregg L. Semenza 63518 3693 14788 68202 418 114.8k
Harvey F. Lodish 46181 3750 6241 10840 572 76.6k
Napoleone Ferrara 60705 3370 4584 23583 257 97.7k
Judah Folkman 62209 2942 5535 29198 391 103.7k
Steven P. Gygi 87120 2334 7477 11525 689 119.3k

All Works

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2026