Standout Papers

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain ... 1993 2026 2004 2015 1.8k
  1. Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs (1994)
    Alfred H. Schinkel, Jasper Smit et al. Cell
  2. Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease (1993)
    Jasper Smit, Alfred H. Schinkel et al. Cell
  3. P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs. (1996)
    Alfred H. Schinkel, Els Wagenaar et al. Journal of Clinical Investigation
  4. Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A. (1995)
    Alfred H. Schinkel, Els Wagenaar et al. Journal of Clinical Investigation
  5. Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins (1997)
    Alfred H. Schinkel, Ulrich Mayer et al. Proceedings of the National Academy of Sciences
  6. The Drosophila homology of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless (1987)
    Frans A.M. Rijsewijk, Marcus Schuermann et al. Cell
  7. The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria (2002)
    Johan W. Jonker, Marije Buitelaar et al. Proceedings of the National Academy of Sciences

Immediate Impact

33 by Nobel laureates 82 from Science/Nature 116 standout
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Citing Papers

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6 intermediate papers

Works of Els Wagenaar being referenced

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
1994 Standout
Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
1993 Standout
and 9 more

Author Peers

Author Last Decade Papers Cites
Els Wagenaar 10040 5013 4283 97 13.9k
George L. Scheffer 10449 4061 5292 140 14.7k
Raymond Evers 5767 2736 2732 99 9.1k
I Pastan 8341 2633 4679 47 10.8k
Balázs Sarkadi 7787 2571 6518 228 14.2k
Johan W. Jonker 4947 2286 3898 99 10.1k
Ulrich Brinkmann 5269 2431 5196 180 12.2k
R G Deeley 5300 1738 3563 60 8.2k
András Váradi 4699 1449 3072 116 8.0k
Irwin M. Arias 3338 2768 4375 195 9.9k
Frances J. Sharom 5175 1488 4446 140 8.6k

All Works

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