Standout Papers

TFEB Links Autophagy to Lysosomal Biogenesis 2004 2026 2011 2018 2.4k
  1. TFEB Links Autophagy to Lysosomal Biogenesis (2011)
    Carmine Settembre, Chiara Di Malta et al. Science
  2. Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease (2004)
    Brinda Ravikumar, Corinne Vacher et al. Nature Genetics
  3. Regulation of Mammalian Autophagy in Physiology and Pathophysiology (2010)
    Brinda Ravikumar, Sovan Sarkar et al. Physiological Reviews
  4. The roles of intracellular protein-degradation pathways in neurodegeneration (2006)
    David C. Rubinsztein Nature
  5. Autophagy modulation as a potential therapeutic target for diverse diseases (2012)
    David C. Rubinsztein, Patrice Codogno et al. Nature Reviews Drug Discovery
  6. α-Synuclein Is Degraded by Both Autophagy and the Proteasome (2003)
    Brinda Ravikumar, Jane T. Atkins et al. Journal of Biological Chemistry
  7. Trehalose, a Novel mTOR-independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and α-Synuclein (2006)
    Sovan Sarkar, J. Eric Davies et al. Journal of Biological Chemistry
  8. Potential therapeutic applications of autophagy (2007)
    David C. Rubinsztein, Jason E. Gestwicki et al. Nature Reviews Drug Discovery
  9. Lithium induces autophagy by inhibiting inositol monophosphatase (2005)
    Sovan Sarkar, R. Andres Floto et al. The Journal of Cell Biology
  10. Autophagy in healthy aging and disease (2021)
    Yahyah Aman, Tomas Schmauck‐Medina et al. Nature Aging
  11. Plasma membrane contributes to the formation of pre-autophagosomal structures (2010)
    Brinda Ravikumar, Kévin Moreau et al. Nature Cell Biology
  12. Lysosomal positioning coordinates cellular nutrient responses (2011)
    Viktor I. Korolchuk, Shinji Saiki et al. Nature Cell Biology
  13. α-Synuclein impairs macroautophagy: implications for Parkinson’s disease (2010)
    Ashley R. Winslow, Chien‐Wen Chen et al. The Journal of Cell Biology
  14. Compromised autophagy and neurodegenerative diseases (2015)
    Fiona M. Menzies, Angeleen Fleming et al. Nature reviews. Neuroscience
  15. Novel targets for Huntington's disease in an mTOR-independent autophagy pathway (2008)
    Sovan Sarkar, Paul A. Cuddon et al. Nature Chemical Biology
  16. Mammalian Autophagy: How Does It Work? (2016)
    Carla F. Bento, Maurizio Renna et al. Annual Review of Biochemistry
  17. Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates (2009)
    Viktor I. Korolchuk, Alicia Mansilla et al. Molecular Cell
  18. Autophagy as a promoter of longevity: insights from model organisms (2018)
    Malene Hansen, David C. Rubinsztein et al. Nature Reviews Molecular Cell Biology
  19. Rapamycin alleviates toxicity of different aggregate-prone proteins (2005)
    Zdenek Berger, Brinda Ravikumar et al. Human Molecular Genetics
  20. Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing (2018)
    Barry Boland, Wai Haung Yu et al. Nature Reviews Drug Discovery
  21. Mutation in VPS35 associated with Parkinson’s disease impairs WASH complex association and inhibits autophagy (2014)
    Eszter Zavodszky, Matthew Seaman et al. Nature Communications
  22. Huntington’s Disease: Mechanisms of Pathogenesis and Therapeutic Strategies (2016)
    María Jiménez-Sánchez, Floriana Licitra et al. Cold Spring Harbor Perspectives in Medicine
  23. LC3-positive structures are prominent in autophagy-deficient cells (2019)
    Gautam Runwal, Eleanna Stamatakou et al. Scientific Reports
  24. The different autophagy degradation pathways and neurodegeneration (2022)
    Angeleen Fleming, Mathieu Bourdenx et al. Neuron
  25. Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases (2024)
    Ralph A. Nixon, David C. Rubinsztein Nature Reviews Molecular Cell Biology
  26. Autophagy, aging, and age-related neurodegeneration (2024)
    Niall Wilson, Sung Min Son et al. Neuron

Immediate Impact

18 by Nobel laureates 87 from Science/Nature 384 standout
Sub-graph 1 of 11

Citing Papers

Mitochondrial transfer mediates endothelial cell engraftment through mitophagy
2024 StandoutNature
Lysosomes drive the piecemeal removal of mitochondrial inner membrane
2024 StandoutNature

Works of David C. Rubinsztein being referenced

Mammalian Autophagy: How Does It Work?
2016 Standout
Cytoprotective roles for autophagy
2010

Author Peers

Author Last Decade Papers Cites
David C. Rubinsztein 21964 21262 9754 9858 352 45.8k
Ana María Cuervo 29935 20769 4147 13815 251 51.4k
Richard J. Youle 19968 43318 4682 6539 238 61.8k
Ralph A. Nixon 8358 14271 7266 11160 320 37.0k
Keiji Tanaka 19640 37364 2989 11397 427 54.1k
Masaaki Komatsu 28700 21454 1756 8260 223 44.9k
Junying Yuan 10840 35952 4613 8020 251 51.9k
Valina L. Dawson 6754 26519 15618 4813 376 55.6k
Andrea Ballabio 12737 19755 2888 7802 373 39.4k
Ted M. Dawson 7002 28571 19189 5227 427 60.8k
Paul Säftig 6390 18628 3615 7785 327 38.5k

All Works

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2026