Standout Papers

Nitric oxide as a secretory product of mammalian cells 1987 2026 2000 2013 3.7k
  1. Nitric oxide as a secretory product of mammalian cells (1992)
    Carl Nathan The FASEB Journal
  2. NITRIC OXIDE AND MACROPHAGE FUNCTION (1997)
    John D. MacMicking, Q W Xie et al. Annual Review of Immunology
  3. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production. (1988)
    Aihao Ding, Carl Nathan et al. The Journal of Immunology
  4. Nitric oxide synthases: Roles, tolls, and controls (1994)
    Carl Nathan, Q W Xie Cell
  5. Secretory products of macrophages. (1987)
    Carl Nathan Journal of Clinical Investigation
  6. Neutrophils and immunity: challenges and opportunities (2006)
    Carl Nathan Nature reviews. Immunology
  7. Production of large amounts of hydrogen peroxide by human tumor cells. (1991)
    Ted P. Szatrowski, Carl Nathan PubMed
  8. Points of control in inflammation (2002)
    Carl Nathan Nature
  9. Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase. (1994)
    Yumiko Kashiwabara, Carl Nathan et al. Journal of Biological Chemistry
  10. Cloning and Characterization of Inducible Nitric Oxide Synthase from Mouse Macrophages (1992)
    Q W Xie, Hearn Jay Cho et al. Science
  11. Nonresolving Inflammation (2010)
    Carl Nathan, Aihao Ding Cell
  12. Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity. (1983)
    Carl Nathan, Henry W. Murray et al. The Journal of Experimental Medicine
  13. Nitric oxide. A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cells. (1989)
    Dennis J. Stuehr, Carl Nathan The Journal of Experimental Medicine
  14. Regulation of biosynthesis of nitric oxide. (1994)
    Carl Nathan et al. Journal of Biological Chemistry
  15. Role of nitric oxide synthesis in macrophage antimicrobial activity (1991)
    Carl Nathan, John B. Hibbs Current Opinion in Immunology
  16. Beyond oxidative stress: an immunologist's guide to reactive oxygen species (2013)
    Carl Nathan, Amy Cunningham‐Bussel Nature reviews. Immunology
  17. Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens (2000)
    Carl Nathan, Michael U. Shiloh Proceedings of the National Academy of Sciences
  18. Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages (2003)
    Dirk Schnappinger, Sabine Ehrt et al. The Journal of Experimental Medicine
  19. Macrophage deactivation by interleukin 10. (1991)
    Christian Bogdan, Yoram Vodovotz et al. The Journal of Experimental Medicine
  20. Identification of nitric oxide synthase as a protective locus against tuberculosis (1997)
    John D. MacMicking, R J North et al. Proceedings of the National Academy of Sciences
  21. Deactivation of macrophages by transforming growth factor-β (1988)
    Shohko Tsunawaki, Michael B. Sporn et al. Nature
  22. Neutrophil activation on biological surfaces. Massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes. (1987)
    Carl Nathan Journal of Clinical Investigation
  23. Inhibition of Viral Replication by Interferon-γ-Induced Nitric Oxide Synthase (1993)
    Gunasegaran Karupiah, Q W Xie et al. Science
  24. Cytokines in context. (1991)
    Carl Nathan, M Sporn The Journal of Cell Biology
  25. Suppression of arthritis by an inhibitor of nitric oxide synthase. (1993)
    Nancy McCartney‐Francis, J B Allen et al. The Journal of Experimental Medicine
  26. Mechanisms of suppression of macrophage nitric oxide release by transforming growth factor beta. (1993)
    Yoram Vodovotz, Christian Bogdan et al. The Journal of Experimental Medicine
  27. Peroxynitrite reductase activity of bacterial peroxiredoxins (2000)
    Ruslana Bryk, Patrick R. Griffin et al. Nature
  28. The Macrophage as an Effector Cell (1980)
    Carl Nathan, Henry W. Murray et al. New England Journal of Medicine
  29. Conversion of Proepithelin to Epithelins (2002)
    Jing Zhu, Carl Nathan et al. Cell
  30. Reduced Biopterin as a Cofactor in the Generation of Nitrogen Oxides by Murine Macrophages (1989)
    N S Kwon, Carl Nathan et al. Journal of Biological Chemistry
  31. Extracellular cytolysis by activated macrophages and granulocytes. II. Hydrogen peroxide as a mediator of cytotoxicity. (1979)
    Carl Nathan, S C Silverstein et al. The Journal of Experimental Medicine
  32. Glutathione metabolism as a determinant of therapeutic efficacy: a review. (1984)
    Bradley A. Arrick, Carl Nathan PubMed
  33. Hydrogen peroxide release from mouse peritoneal macrophages: dependence on sequential activation and triggering. (1977)
    Carl Nathan, Richard K. Root The Journal of Experimental Medicine
  34. Extracellular cytolysis by activated macrophages and granulocytes. I. Pharmacologic triggering of effector cells and the release of hydrogen peroxide. (1979)
    Carl Nathan, S C Silverstein et al. The Journal of Experimental Medicine
  35. Local and Systemic Effects of Intradermal Recombinant Interferon-γ in Patients with Lepromatous Leprosy (1986)
    Carl Nathan, Gilla Kaplan et al. New England Journal of Medicine
  36. Interferon- γ and infectious diseases: Lessons and prospects (2024)
    Jean‐Laurent Casanova, John D. MacMicking et al. Science

Immediate Impact

25 by Nobel laureates 48 from Science/Nature 131 standout
Sub-graph 1 of 20

Citing Papers

Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Hallmarks of Cancer: The Next Generation
2011 Standout
13 intermediate papers

Works of Carl Nathan being referenced

Modulation of Macrophage Function by Transforming Growth Factor β, Interleukin‐4, and Interleukin‐10a
1993
Production of large amounts of hydrogen peroxide by human tumor cells.
1991 Standout
and 8 more

Author Peers

Author Last Decade Papers Cites
Carl Nathan 23625 21985 8053 17400 316 72.0k
Anthony Cerami 18668 20595 2217 10579 513 75.8k
Paul Kubes 12413 25693 2592 7992 421 51.2k
Stanley L. Hazen 25563 9985 2180 18646 477 53.6k
Charles N. Serhan 22849 23709 1727 11927 614 80.3k
Aldons J. Lusis 30239 10413 1429 11830 615 62.5k
Charles A. Dinarello 36261 46442 5702 9139 864 106.0k
Simon C. Watkins 27957 12746 1824 7769 779 58.2k
Tim R. Mosmann 22363 20566 3251 4605 123 74.0k
Timothy R. Billiar 19196 13863 927 12511 774 56.1k
Luke O'neill 23194 31895 3327 4954 380 59.7k

All Works

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2026