Standout Papers

Critical nodes in signalling pathways: insights into insulin action 2000 2026 2008 2017 2.1k
  1. Critical nodes in signalling pathways: insights into insulin action (2006)
    Cullen M. Taniguchi, Brice Emanuelli et al. Nature Reviews Molecular Cell Biology
  2. Role of Brain Insulin Receptor in Control of Body Weight and Reproduction (2000)
    Jens C. Brüning, Dinesh Gautam et al. Science
  3. Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role ofPGC1andNRF1 (2003)
    Mary‐Elizabeth Patti, Atul J. Butte et al. Proceedings of the National Academy of Sciences
  4. Type 2 diabetes mellitus (2015)
    Ralph A. DeFronzo, Ele Ferrannini et al. Nature Reviews Disease Primers
  5. Suppression of Aging in Mice by the Hormone Klotho (2005)
    Hiroshi Kurosu, Masaya Yamamoto et al. Science
  6. The insulin signaling system. (1994)
    Morris F. White, C. Ronald Kahn Journal of Biological Chemistry
  7. SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation (2010)
    Matthew D. Hirschey, Tadahiro Shimazu et al. Nature
  8. Antioxidants prevent health-promoting effects of physical exercise in humans (2009)
    Michael Ristow, Kim Zarse et al. Proceedings of the National Academy of Sciences
  9. Developmental Origin of Fat: Tracking Obesity to Its Source (2007)
    Stéphane Gesta, Yu‐Hua Tseng et al. Cell
  10. Adipose-derived circulating miRNAs regulate gene expression in other tissues (2017)
    Thomas Thomou, Marcelo A. Mori et al. Nature
  11. Insulin Receptor Signaling in Normal and Insulin-Resistant States (2014)
    Jérémie Boucher, André Kleinridders et al. Cold Spring Harbor Perspectives in Biology
  12. Extended Longevity in Mice Lacking the Insulin Receptor in Adipose Tissue (2003)
    Matthias Blüher, Barbara B. Kahn et al. Science
  13. Loss of Insulin Signaling in Hepatocytes Leads to Severe Insulin Resistance and Progressive Hepatic Dysfunction (2000)
    Rohit Kulkarni, Catherine Postic et al. Molecular Cell
  14. Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study (1992)
    Blaise C. Martin, James H. Warram et al. The Lancet
  15. A Muscle-Specific Insulin Receptor Knockout Exhibits Features of the Metabolic Syndrome of NIDDM without Altering Glucose Tolerance (1998)
    Jens C. Brüning, Jonathon N. Winnay et al. Molecular Cell
  16. Diabetes primes neutrophils to undergo NETosis, which impairs wound healing (2015)
    Siu Ling Wong, Mélanie Demers et al. Nature Medicine
  17. New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure (2008)
    Yu‐Hua Tseng, Efi Kokkotou et al. Nature
  18. The Syndromes of Insulin Resistance and Acanthosis Nigricans (1976)
    C. Ronald Kahn, Jeffrey S. Flier et al. New England Journal of Medicine
  19. Phlorizin: a review (2004)
    Joel Ehrenkranz, Norman Lewis et al. Diabetes/Metabolism Research and Reviews
  20. Extracellular miRNAs: From Biomarkers to Mediators of Physiology and Disease (2019)
    Marcelo A. Mori, Raissa G. Ludwig et al. Cell Metabolism
  21. The changing natural history of nephropathy in type I Diabetes (1985)
    Andrzej S. Królewski, James H. Warram et al. The American Journal of Medicine
  22. Adipose Tissue Selective Insulin Receptor Knockout Protects against Obesity and Obesity-Related Glucose Intolerance (2002)
    Matthias Blüher, Odile D. Peroni et al. Developmental Cell
  23. Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance (2000)
    Ariel Zisman, Odile D. Peroni et al. Nature Medicine
  24. Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185,000 protein in intact cells (1985)
    Morris F. White, Ruth Maron et al. Nature
  25. Beneficial Effects of Subcutaneous Fat Transplantation on Metabolism (2008)
    Thien T. Tran, Yuji Yamamoto et al. Cell Metabolism
  26. Insulin Action in AgRP-Expressing Neurons Is Required for Suppression of Hepatic Glucose Production (2007)
    A. Christine Könner, Ruth Janoschek et al. Cell Metabolism
  27. Suppressor of Cytokine Signaling 1 (SOCS-1) and SOCS-3 Cause Insulin Resistance through Inhibition of Tyrosine Phosphorylation of Insulin Receptor Substrate Proteins by Discrete Mechanisms (2004)
    Kohjiro Ueki, Tatsuya Kondo et al. Molecular and Cellular Biology
  28. Role for neuronal insulin resistance in neurodegenerative diseases (2004)
    Markus Schubert, Dinesh Gautam et al. Proceedings of the National Academy of Sciences
  29. Insulin Action in Brain Regulates Systemic Metabolism and Brain Function (2014)
    André Kleinridders, Heather A. Ferris et al. Diabetes
  30. Membrane receptors for hormones and neurotransmitters. (1976)
    C. Ronald Kahn The Journal of Cell Biology
  31. MicroRNA sequence codes for small extracellular vesicle release and cellular retention (2021)
    Rubén García-Martín, Guoxiao Wang et al. Nature
  32. Altered adipose tissue and adipocyte function in the pathogenesis of metabolic syndrome (2019)
    C. Ronald Kahn, Guoxiao Wang et al. Journal of Clinical Investigation
  33. Receptors and growth-promoting effects of insulin and insulinlike growth factors on cells from bovine retinal capillaries and aorta. (1985)
    George L. King, Andrew Goodman et al. Journal of Clinical Investigation
  34. Insulin resistance in brain alters dopamine turnover and causes behavioral disorders (2015)
    André Kleinridders, Weikang Cai et al. Proceedings of the National Academy of Sciences

Immediate Impact

10 by Nobel laureates 64 from Science/Nature 150 standout
Sub-graph 1 of 13

Citing Papers

The Hallmarks of Aging
2013 Standout
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
2012 StandoutNature
149 intermediate papers

Works of C. Ronald Kahn being referenced

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure
2008 StandoutNature
Endocrine regulation of ageing
2007
and 72 more

Author Peers

Author Last Decade Papers Cites
C. Ronald Kahn 36433 26211 14266 511 73.3k
Jerrold M. Olefsky 34169 24518 12227 588 70.4k
Johan Auwerx 50378 29334 12505 632 94.3k
Bart Staels 40867 17854 16704 781 77.2k
Takashi Kadowaki 24742 16009 10229 858 60.5k
Gerald I. Shulman 48857 44043 19421 614 104.2k
Jeffrey S. Flier 22394 27836 8997 307 79.2k
Gökhan S. Hotamışlıgil 25884 23726 9462 175 70.1k
D. Grahame Hardie 49963 15640 19239 444 69.7k
Morris F. White 32584 11383 12289 343 50.8k
Frank J. Gonzalez 55848 16492 14031 1.3k 117.1k

All Works

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