Standout Papers

A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosyn... 2000 2026 2008 2017 1.6k
  1. A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis (2000)
    Bryan Goodwin, Stacey A. Jones et al. Molecular Cell
  2. Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis (2005)
    Takeshi Inagaki, Mihwa Choi et al. Cell Metabolism
  3. The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity (2001)
    Jeff L. Staudinger, Bryan Goodwin et al. Proceedings of the National Academy of Sciences
  4. The Nuclear Pregnane X Receptor: A Key Regulator of Xenobiotic Metabolism (2002)
    Steven A. Kliewer, Bryan Goodwin et al. Endocrine Reviews
  5. Regulation of Multidrug Resistance-associated Protein 2 (ABCC2) by the Nuclear Receptors Pregnane X Receptor, Farnesoid X-activated Receptor, and Constitutive Androstane Receptor (2002)
    Heidi R. Kast-Woelbern, Bryan Goodwin et al. Journal of Biological Chemistry
  6. St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor (2000)
    Linda B. Moore, Bryan Goodwin et al. Proceedings of the National Academy of Sciences
  7. Orphan Nuclear Receptors Constitutive Androstane Receptor and Pregnane X Receptor Share Xenobiotic and Steroid Ligands (2000)
    Linda B. Moore, Derek J. Parks et al. Journal of Biological Chemistry
  8. The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation ofCYP3A4by Rifampicin through a Distal Enhancer Module (1999)
    Bryan Goodwin, Christopher Liddle et al. Molecular Pharmacology
  9. Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis (2003)
    Jason A. Holt, Guizhen Luo et al. Genes & Development
  10. Nuclear Pregnane X Receptor and Constitutive Androstane Receptor Regulate Overlapping but Distinct Sets of Genes Involved in Xenobiotic Detoxification (2002)
    Jodi M. Maglich, Bryan Goodwin et al. Molecular Pharmacology
  11. A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects (2016)
    Saswata Talukdar, Yingjiang Zhou et al. Cell Metabolism

Immediate Impact

7 by Nobel laureates 15 from Science/Nature 104 standout
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Citing Papers

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The gut metabolite indole-3 propionate promotes nerve regeneration and repair
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Works of Bryan Goodwin being referenced

A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects
2016 Standout
The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity
2001 Standout

Author Peers

Author Last Decade Papers Cites
Bryan Goodwin 6429 4891 4534 69 13.9k
Stacey A. Jones 6712 3489 5398 37 13.8k
Linda B. Moore 4479 3304 7064 44 13.6k
John Y.L. Chiang 7622 2193 6149 162 15.7k
Barry M. Forman 4365 1569 10359 79 17.3k
Christopher Liddle 2933 2445 4377 155 14.1k
Erin G. Schuetz 9575 9748 4691 198 19.7k
Derek J. Parks 3417 1333 4289 39 9.3k
Kristopher W. Krausz 3289 3350 6649 201 13.3k
Philip S. Guzelian 3447 5897 2369 119 9.8k
Jürgen M. Lehmann 3907 1659 11534 37 17.4k

All Works

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