Standout Papers

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and ly... 1993 2026 2004 2015 2.7k
  1. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis (1999)
    Young‐Yun Kong, Hiroki Yoshida et al. Nature
  2. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection (1993)
    Klaus Pfeffer, T. Matsuyama et al. Cell
  3. Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death (2001)
    Nicholas Joza, Santos A. Susín et al. Nature
  4. Differential T Cell Costimulatory Requirements in CD28-Deficient Mice (1993)
    Arda Shahinian, Klaus Pfeffer et al. Science
  5. DNA Damage-Induced Activation of p53 by the Checkpoint Kinase Chk2 (2000)
    Atsushi Hirao, Young‐Yun Kong et al. Science
  6. Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration (2000)
    Takehiko Sasaki, Junko Irie-Sasaki et al. Science
  7. Profound block in thymocyte development in mice lacking p56lck (1992)
    Thierry Jo Molina, Kenji Kishihara et al. Nature
  8. FADD: Essential for Embryo Development and Signaling from Some, But Not All, Inducers of Apoptosis (1998)
    Wen‐Chen Yeh, José Luís de la Pompa et al. Science
  9. Deregulated T Cell Activation and Autoimmunity in Mice Lacking Interleukin-2 Receptor β (1995)
    Haruhiko Suzuki, Thomas M. Kündig et al. Science
  10. Early Lethality, Functional NF-κB Activation, and Increased Sensitivity to TNF-Induced Cell Death in TRAF2-Deficient Mice (1997)
    Wen-Chen Yeh, Arda Shahinian et al. Immunity
  11. High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice (1998)
    Akira Suzuki, José Luís de la Pompa et al. Current Biology
  12. Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4 (2002)
    Nobutaka Suzuki, Shinobu Suzuki et al. Nature
  13. Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4 (1991)
    Amin Rahemtulla, Wai‐Ping Fung‐Leung et al. Nature
  14. Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development (1993)
    T. Matsuyama, Tohru Kimura et al. Cell
  15. Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress (2005)
    Raymond H. Kim, Patrice D. Smith et al. Proceedings of the National Academy of Sciences
  16. ICOS is essential for effective T-helper-cell responses (2001)
    Agostino Tafuri, Arda Shahinian et al. Nature
  17. Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b (2000)
    Kurt Bachmaier, Connie M. Krawczyk et al. Nature
  18. The Tumor Suppressor Gene Brca1 Is Required for Embryonic Cellular Proliferation in the Mouse (1996)
    Razqallah Hakem, José Luís de la Pompa et al. Cell
  19. Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum (1998)
    José Luís de la Pompa, Luika Timmerman et al. Nature
  20. Conservation of the Notch signalling pathway in mammalian neurogenesis (1997)
    José Luís de la Pompa, Andrew Wakeham et al. Development
  21. T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance (2001)
    Akira Suzuki, Toshiaki Ohteki et al. Immunity
  22. Disruption of the mouse RBP-Jк gene results in early embryonic death (1995)
    Chio Oka, Toru Nakano et al. Development

Immediate Impact

25 by Nobel laureates 61 from Science/Nature 136 standout
Sub-graph 1 of 21

Citing Papers

Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
2015 StandoutNature
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
4 intermediate papers

Works of Andrew Wakeham being referenced

The Transcription Factor NF-ATc1 Regulates Lymphocyte Proliferation and Th2 Cytokine Production
1998
Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development
1993 Standout
and 1 more

Author Peers

Author Last Decade Papers Cites
Andrew Wakeham 17103 13194 7809 111 31.1k
William J. Henzel 16172 6358 4187 116 28.4k
Michael J. Lenardo 14787 17351 6343 243 33.6k
Manolis Pasparakis 13098 12179 4214 193 26.1k
Jacques J. Peschon 8979 11397 5805 92 24.6k
Ulrich Siebenlist 10467 10444 4308 175 22.2k
Peter Angel 17609 5062 5879 185 28.8k
Suzanne Cory 22945 8380 7858 182 33.9k
Yongwon Choi 14078 12175 8790 210 27.2k
Brian Seed 17702 11709 4994 154 32.9k
Pamela S. Ohashi 9915 22791 7137 313 33.1k

All Works

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